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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5jjsSAHGenome polyprotein

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5jjsSAHGenome polyprotein/1.000
5jjrSAHGenome polyprotein/0.687
3p8z36AGenome polyprotein2.1.1.560.586
4ctjSAMGenome polyprotein/0.572
3p97SAMGenome polyprotein2.1.1.560.554
3p8zSAHGenome polyprotein2.1.1.560.552
3eldSFGMethyltransferase/0.547
2p41SAHGenome polyprotein/0.546
4k6mSAHGenome polyprotein/0.546
4ctkSAMGenome polyprotein/0.545
2pxaSAHGenome polyprotein2.7.7.480.539
3eluSAMMethyltransferase/0.539
3elySAHMethyltransferase/0.531
3evcSAHGenome polyprotein2.1.1.560.530
2wa2SAMGenome polyprotein/0.519
2px5SAHGenome polyprotein2.7.7.480.514
2px2SAHGenome polyprotein2.7.7.480.478
2oxtSAMGenome polyprotein/0.458
2xbmSAHGenome polyprotein/0.450