sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5jj0 | SAM | Histone-lysine N-methyltransferase EHMT2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5jj0 | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 1.000 | |
| 5jhn | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.692 | |
| 3hna | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.611 | |
| 5jin | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.603 | |
| 4nvq | 2OD | Histone-lysine N-methyltransferase EHMT2 | / | 0.602 | |
| 2o8j | SAH | Histone-lysine N-methyltransferase EHMT2 | / | 0.560 | |
| 3fpd | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.559 | |
| 3mo0 | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.549 | |
| 3mo5 | E72 | Histone-lysine N-methyltransferase EHMT1 | / | 0.512 | |
| 3mo0 | E11 | Histone-lysine N-methyltransferase EHMT1 | / | 0.480 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.469 | |
| 3kmt | SAH | Histone H3K27 methylase | / | 0.459 | |
| 1mlv | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.442 | |
| 2igq | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.442 | |
| 4e47 | 0N6 | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 0.440 |