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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5jinSAMHistone-lysine N-methyltransferase EHMT2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5jinSAMHistone-lysine N-methyltransferase EHMT2/1.000
2o8jSAHHistone-lysine N-methyltransferase EHMT2/0.595
5jhnSAMHistone-lysine N-methyltransferase EHMT2/0.594
3hnaSAHHistone-lysine N-methyltransferase EHMT1/0.593
4nvq2ODHistone-lysine N-methyltransferase EHMT2/0.588
5jj0SAMHistone-lysine N-methyltransferase EHMT2/0.585
3fpdSAHHistone-lysine N-methyltransferase EHMT1/0.580
3mo0SAHHistone-lysine N-methyltransferase EHMT1/0.553
3mo5E72Histone-lysine N-methyltransferase EHMT1/0.513
3kmtSAHHistone H3K27 methylase/0.498
3mo0E11Histone-lysine N-methyltransferase EHMT1/0.479
2igqSAHHistone-lysine N-methyltransferase EHMT1/0.475