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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5idwNAPShort-chain dehydrogenase/reductase SDR

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5idwNAPShort-chain dehydrogenase/reductase SDR/1.000
1snyNAPLD36273p/0.513
4j7xNAPSepiapterin reductase1.1.1.1530.501
1n5dNDPCarbonyl reductase [NADPH] 1/0.498
4j7uNAPSepiapterin reductase1.1.1.1530.491
4hwkNAPSepiapterin reductase1.1.1.1530.488
1edoNAP3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic1.1.1.1000.483
1ipeNDPTropinone reductase 21.1.1.2360.476
1oaaNAPSepiapterin reductase1.1.1.1530.474
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.472
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.468
1ae1NAPTropinone reductase 1/0.460
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.459
1x7gNAPPutative ketoacyl reductase1.3.10.456
1x7hNDPPutative ketoacyl reductase1.3.10.455
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.455
4bmvNAPShort-chain dehydrogenase/0.455
1w4zNAPPutative ketoacyl reductase1.3.10.454
3u4cNDPNADPH-dependent reductase BacG/0.453
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.451
1xg5NAPDehydrogenase/reductase SDR family member 11/0.448
2bd0NAPSepiapterin reductase/0.448
1xkqNDPUncharacterized protein/0.447
2dknNAI3-alpha-hydroxysteroid dehydrogenase/0.446
4i5eNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.446
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.443
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.442
3p19NDPPutative blue fluorescent protein/0.440
3sjuNDPKeto reductase/0.440
3toxNAPPutative oxidoreductase/0.440