sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5fsx | ADP | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5fsx | ADP | Uncharacterized protein | / | 1.000 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.518 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.516 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.502 | |
| 3sii | A1R | Uncharacterized protein | / | 0.485 | |
| 5cb5 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.484 | |
| 3ewr | APR | Replicase polyprotein 1a | 3.4.22 | 0.480 | |
| 5fsy | AR6 | Uncharacterized protein | / | 0.463 | |
| 3sig | AR6 | Uncharacterized protein | / | 0.457 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.451 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.449 | |
| 2fav | APR | Nonstructural polyprotein pp1a | / | 0.449 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.443 |