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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5f59SAHHistone-lysine N-methyltransferase 2C2.1.1.43

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5f59SAHHistone-lysine N-methyltransferase 2C2.1.1.431.000
4qenSAHHistone-lysine N-methyltransferase, H3 lysine-9 specific SUVH42.1.1.430.487
2zsaADPPantothenate kinase2.7.1.330.457
4ypuSAMHistone-lysine N-methyltransferase ASH1L2.1.1.430.457
4z4pSAHHistone-lysine N-methyltransferase 2D2.1.1.430.457
4rvfTYDD-mycarose 3-C-methyltransferase/0.451
2o8jSAHHistone-lysine N-methyltransferase EHMT2/0.444
3mo0SAHHistone-lysine N-methyltransferase EHMT1/0.442