Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
5dt4 | ATP | Aurora kinase A | 2.7.11.1 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
5dt4 | ATP | Aurora kinase A | 2.7.11.1 | 1.000 | |
5dos | ATP | Aurora kinase A | 2.7.11.1 | 0.683 | |
5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.662 | |
2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.592 | |
5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.589 | |
3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.585 | |
4dee | ADP | Aurora kinase A | 2.7.11.1 | 0.582 | |
5dn3 | ATP | Aurora kinase A | 2.7.11.1 | 0.580 | |
1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.572 | |
4jbp | YPH | Aurora kinase A | 2.7.11.1 | 0.569 | |
5dr9 | SKE | Aurora kinase A | 2.7.11.1 | 0.568 | |
1mq4 | ADP | Aurora kinase A | 2.7.11.1 | 0.559 | |
2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.550 | |
4o0w | ADN | Aurora kinase A | 2.7.11.1 | 0.546 | |
5dnr | ATP | Aurora kinase A | 2.7.11.1 | 0.546 | |
4utd | ACP | Aurora kinase A | 2.7.11.1 | 0.542 | |
4c3r | ACP | Aurora kinase A | 2.7.11.1 | 0.534 | |
1ol7 | ADP | Aurora kinase A | 2.7.11.1 | 0.533 | |
5dr2 | ATP | Aurora kinase A | 2.7.11.1 | 0.529 | |
3uo5 | 0BX | Aurora kinase A | 2.7.11.1 | 0.524 | |
3c50 | ADP | Rhodopsin kinase | / | 0.523 | |
4dea | NHI | Aurora kinase A | 2.7.11.1 | 0.521 | |
1ol6 | ATP | Aurora kinase A | 2.7.11.1 | 0.520 | |
2w1g | L0G | Aurora kinase A | 2.7.11.1 | 0.517 | |
4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.516 | |
5dt0 | SKE | Aurora kinase A | 2.7.11.1 | 0.516 | |
4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.515 | |
2x6d | X6D | Aurora kinase A | 2.7.11.1 | 0.514 | |
4o0u | ADN | Aurora kinase A | 2.7.11.1 | 0.513 | |
3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.512 | |
4o0s | ADN | Aurora kinase A | 2.7.11.1 | 0.511 | |
1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.510 | |
1pyx | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.509 | |
4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.508 | |
2xng | A0H | Aurora kinase A | 2.7.11.1 | 0.507 | |
3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.506 | |
2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.504 | |
3w18 | N13 | Aurora kinase A | 2.7.11.1 | 0.504 | |
3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.502 | |
2xru | 400 | Aurora kinase A | 2.7.11.1 | 0.501 | |
2np8 | CC3 | Aurora kinase A | 2.7.11.1 | 0.499 | |
3t8o | ATP | Rhodopsin kinase | / | 0.499 | |
4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.497 | |
4ceg | ADP | Aurora kinase A | 2.7.11.1 | 0.496 | |
4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.496 | |
2wqe | ADP | Aurora kinase A | 2.7.11.1 | 0.495 | |
4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.494 | |
5dmz | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.494 | |
4dn5 | AGS | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.493 | |
2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.492 | |
3w16 | P9J | Aurora kinase A | 2.7.11.1 | 0.492 | |
1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.491 | |
3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.491 | |
3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.491 | |
4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.491 | |
4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.491 | |
3ori | AGS | Serine/threonine protein kinase | / | 0.490 | |
4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.490 | |
1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.489 | |
2w4k | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.489 | |
2xne | ASH | Aurora kinase A | 2.7.11.1 | 0.489 | |
4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.489 | |
1uv5 | BRW | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.488 | |
1u54 | ACP | Activated CDC42 kinase 1 | / | 0.487 | |
4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.487 | |
5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.487 | |
1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.486 | |
2w1d | L0D | Aurora kinase A | 2.7.11.1 | 0.486 | |
3c4z | ADP | Rhodopsin kinase | / | 0.486 | |
3mfu | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.484 | |
4dgm | AGI | Casein kinase II subunit alpha | 2.7.11.1 | 0.484 | |
4qpm | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.484 | |
5dpv | SKE | Aurora kinase A | 2.7.11.1 | 0.484 | |
3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.483 | |
4ysj | ADP | Calmodulin-like domain protein kinase | / | 0.483 | |
2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.482 | |
2w1e | L0E | Aurora kinase A | 2.7.11.1 | 0.482 | |
4b0g | VEK | Aurora kinase A | 2.7.11.1 | 0.481 | |
2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.479 | |
5amn | DTQ | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.479 | |
1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.478 | |
4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.478 | |
4c3p | ACP | Aurora kinase A | 2.7.11.1 | 0.477 | |
4fl1 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.476 | |
2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.475 | |
2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.475 | |
2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
3c4w | ATP | Rhodopsin kinase | / | 0.474 | |
3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.473 | |
4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.473 | |
4oau | ADP | 2-5A-dependent ribonuclease | 3.1.26 | 0.473 | |
4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.473 | |
2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.472 | |
2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.472 | |
3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.472 | |
3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.472 | |
3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.472 | |
2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.471 | |
2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
4ftj | H8K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.471 | |
2c6t | DT5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
4k8a | K8A | Focal adhesion kinase 1 | 2.7.10.2 | 0.470 | |
1phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.469 | |
3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.469 | |
4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.469 | |
1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
4hvg | 19Q | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.468 | |
5awm | ANP | Stress-activated protein kinase JNK | 2.7.11.24 | 0.468 | |
1oit | HDT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
1q8y | ADP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.467 | |
2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.467 | |
4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.467 | |
1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
3oro | AGS | Serine/threonine protein kinase | / | 0.466 | |
4yhj | AN2 | G protein-coupled receptor kinase 4 | 2.7.11.16 | 0.466 | |
2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.465 | |
2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.465 | |
3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.465 | |
4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.465 | |
1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.464 | |
2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.464 | |
3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.464 | |
3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.464 | |
3qc9 | ADP | Rhodopsin kinase | / | 0.463 | |
4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.463 | |
5e92 | ANP | TGF-beta receptor type-2 | 2.7.11.30 | 0.463 | |
1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.462 | |
1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.462 | |
1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.462 | |
2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.462 | |
4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.462 | |
1day | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.461 | |
1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.461 | |
2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
3a7j | ADP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.461 | |
3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.461 | |
3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
4eom | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.460 | |
3nie | ANP | Mitogen-activated protein kinase | / | 0.460 | |
3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.460 | |
3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.460 | |
4acd | GR9 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.460 | |
4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.460 | |
4eos | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 0.460 | |
4ux9 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.460 | |
2c6e | HPM | Aurora kinase A | 2.7.11.1 | 0.459 | |
2j9m | PY8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
2r64 | 740 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.459 | |
3llt | ANP | Protein serine/threonine kinase-1 | / | 0.459 | |
3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.459 | |
1ogu | ST8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.458 | |
4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.458 | |
4bn1 | ADP | Aurora kinase A | 2.7.11.1 | 0.458 | |
4oav | ACP | 2-5A-dependent ribonuclease | 3.1.26 | 0.458 | |
4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.458 | |
5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.458 | |
5l8l | ADP | Aurora kinase A | 2.7.11.1 | 0.458 | |
2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
2cke | IQU | Death-associated protein kinase 2 | / | 0.457 | |
2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
2x2m | X2M | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.457 | |
2yiq | YIQ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.457 | |
4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
1jst | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.456 | |
1o6y | ACP | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.456 | |
1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.456 | |
2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.456 | |
4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.456 | |
4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.455 | |
2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
2vuw | 5ID | Serine/threonine-protein kinase haspin | 2.7.11.1 | 0.455 | |
2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.455 | |
3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.455 | |
3cgo | JNO | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.455 | |
3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.455 | |
4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.455 | |
4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.455 | |
1daw | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
1ke6 | LS2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
1qmz | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.454 | |
3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
3m42 | HGF | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.454 | |
4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.454 | |
4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.454 | |
4fsm | HK1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.453 | |
2ycs | NXP | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.453 | |
3at3 | ATK | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
3nsz | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
3q4z | ANP | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.453 | |
4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.453 | |
4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.453 | |
1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
2ivv | PP1 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.452 | |
2xm9 | LWH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.452 | |
3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.451 | |
2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.451 | |
4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.451 | |
4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.451 | |
4gvj | ADP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.451 | |
4hgt | 15G | Casein kinase I isoform delta | 2.7.11.1 | 0.451 | |
1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.450 | |
3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
4krc | AGS | Cyclin-dependent protein kinase PHO85 | 2.7.11.22 | 0.450 | |
4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.450 | |
1g6c | IFP | Thiamine-phosphate synthase | / | 0.449 | |
1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.449 | |
2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.449 | |
3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.449 | |
4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.449 | |
4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.449 | |
4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.449 | |
4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
2jkq | VG8 | Focal adhesion kinase 1 | 2.7.10.2 | 0.448 | |
2r5t | ANP | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.448 | |
2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.448 | |
3c4x | ATP | Rhodopsin kinase | / | 0.448 | |
3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
4i4e | 1BQ | Focal adhesion kinase 1 | 2.7.10.2 | 0.448 | |
4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.448 | |
4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.448 | |
2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.447 | |
4fl3 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.447 | |
4ft9 | H4K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
4g16 | 0VM | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.447 | |
4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.447 | |
4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.447 | |
5av4 | GEN | Death-associated protein kinase 1 | 2.7.11.1 | 0.447 | |
5c03 | AGS | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.447 | |
1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.446 | |
1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.446 | |
2euf | LQQ | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.446 | |
3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.446 | |
3eb0 | DRK | Uncharacterized protein | / | 0.446 | |
3hyo | ADP | Pyridoxal kinase | / | 0.446 | |
3ibq | ATP | Pyridoxal kinase | / | 0.446 | |
3mfr | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.446 | |
3ork | AGS | Serine/threonine protein kinase | / | 0.446 | |
3wi6 | YRZ | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.446 | |
4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.446 | |
4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.446 | |
4jrn | ANP | Rhoptry kinase family protein | / | 0.446 | |
4xlv | ACP | Insulin receptor | 2.7.10.1 | 0.446 | |
2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
3fi3 | JK2 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
3w2c | N15 | Aurora kinase A | 2.7.11.1 | 0.445 | |
3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.445 | |
3zxt | ACP | Death-associated protein kinase 1 | 2.7.11.1 | 0.445 | |
4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
4c2u | ANP | DNA helicase | / | 0.445 | |
4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.445 | |
4eoo | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
4gu9 | 4GU | Focal adhesion kinase 1 | 2.7.10.2 | 0.445 | |
4lrj | ANP | Uncharacterized protein | / | 0.445 | |
4o1p | ANP | Ribonuclease L | / | 0.445 | |
1ckp | PVB | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.444 | |
1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.444 | |
1zlt | HYM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.444 | |
2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
2ijm | ADP | Focal adhesion kinase 1 | 2.7.10.2 | 0.444 | |
2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.444 | |
4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.444 | |
4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
1byg | STU | Tyrosine-protein kinase CSK | / | 0.443 | |
1csn | ATP | Casein kinase I homolog 1 | 2.7.11.1 | 0.443 | |
1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.443 | |
2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.443 | |
2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
2z3u | CRR | Cytochrome P450 | / | 0.443 | |
3q9z | TXQ | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
4gfo | 0X2 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.443 | |
4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.443 | |
5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.443 | |
1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.442 | |
1p4f | DRG | Death-associated protein kinase 1 | 2.7.11.1 | 0.442 | |
1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
1u5r | ATP | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.442 | |
1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.442 | |
2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.442 | |
2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.442 | |
3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.442 | |
3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.442 | |
4ez3 | 0S0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
4fl2 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.442 | |
4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
5auv | AGI | Death-associated protein kinase 1 | 2.7.11.1 | 0.442 | |
1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
1mru | AGS | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.441 | |
1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.441 | |
2pzi | AXX | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.441 | |
2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.441 | |
3r8v | Z62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
4bdg | P3J | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.441 | |
4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.440 | |
2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
2x2l | X2L | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.440 | |
3f88 | 3HT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.440 | |
3orm | AGS | Serine/threonine protein kinase | / | 0.440 | |
4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.440 | |
4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
4c4j | X21 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.440 | |
4fkp | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
4fta | H5K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
4y95 | 746 | Tyrosine-protein kinase | / | 0.440 |