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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5cxxFERFae1A

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
5cxxFERFae1A/1.000
3w0uHPWLactoylglutathione lyase4.4.1.50.533
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.522
1p4r354Bifunctional purine biosynthesis protein PURH2.1.2.30.518
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.517
4twnB96Ephrin type-A receptor 32.7.10.10.515
3b9lAZZSerum albumin/0.512
4rrgA3TThreonine--tRNA ligase6.1.1.30.512
1upw444Oxysterols receptor LXR-beta/0.510
3sfxJANUncharacterized protein/0.510
3vg9ZMAAdenosine receptor A2a/0.509
3aosJH2Hemolymph juvenile hormone binding protein/0.508
3up3XCAaceDAF-12/0.507
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.503
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.503
4xbaGMPAprataxin-like protein30.503
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.502
4rvnCOAPhenylacetate-coenzyme A ligase/0.502
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.501
1kw0H4BPhenylalanine-4-hydroxylase1.14.16.10.500
1o6qR17Squalene--hopene cyclase4.2.1.1290.500
1wxyFRKAdenosine deaminase3.5.4.40.498
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.498
4p9dTMPDeoxycytidylate deaminase/0.496
5k2cZMAAdenosine receptor A2a/0.496
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.495
2v61C18Amine oxidase [flavin-containing] B1.4.3.40.495
3w0aDS5Vitamin D3 receptor/0.495
4g2i0VQVitamin D3 receptor/0.495
4ggzBTNBll1558 protein/0.495
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.494
3h3qH13Collagen type IV alpha-3-binding protein/0.493
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.493
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.493
4obuPLPPyridoxal-dependent decarboxylase domain protein/0.493
2bxqIMNSerum albumin/0.491
3pn1IVHDNA ligase/0.491
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.490
3ix4TX1Transcriptional activator protein LasR/0.490
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.490
1lnmDTXBilin-binding protein/0.489
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.489
4bis8HQLysine-specific demethylase 4A1.14.110.489
4py243EMethionine--tRNA ligase/0.489
2bf7HBIPteridine reductase 11.5.1.330.488
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.488
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.488
3up0D7SaceDAF-12/0.488
1h36R88Squalene--hopene cyclase4.2.1.1290.487
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.487
5k2bZMAAdenosine receptor A2a/0.487
1n4qLYS_CYS_VAL_ILE_LEUGeranylgeranyl transferase type-1 subunit beta2.5.1.590.486
1txtCAAHMG-CoA synthase/0.486
3q7fED2Uncharacterized protein/0.486
3sfy3FYUncharacterized protein/0.486
3vf60H6Glucokinase2.7.1.20.486
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.486
4lngJANCaaX farnesyltransferase beta subunit Ram1/0.486
5jtbZMAAdenosine receptor A2a/0.486
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.485
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.485
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.485
3sfh1DIHistone deacetylase 83.5.1.980.485
4epq0RRPoly(ADP-ribose) glycohydrolase/0.485
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.485
1m9nAMZBifunctional purine biosynthesis protein PURH2.1.2.30.484
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.484
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.484
5iu86DZAdenosine receptor A2a/0.484
5uviZMAAdenosine receptor A2a/0.484
1qipGNBLactoylglutathione lyase4.4.1.50.483
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.483
2wmdZZ0NmrA-like family domain-containing protein 1/0.483
2zevIPEGeranylgeranyl pyrophosphate synthase/0.483
4uy6SAHHistidine N-alpha-methyltransferase/0.483
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.483
2fl2ADPKinesin-like protein KIF11/0.482
4a81DXCMajor pollen allergen Bet v 1-A/0.482
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.482
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.481
1nw5SAMModification methylase RsrI2.1.1.720.481
4b66NAPL-ornithine N(5)-monooxygenase/0.481
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.480
1lkeDOGBilin-binding protein/0.480
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.480
1uzwCDHIsopenicillin N synthase1.21.3.10.480
2b1i93ABifunctional purine biosynthesis protein PURH2.1.2.30.480
3pdqKC6Lysine-specific demethylase 4A1.14.110.480
4yddMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.480
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.479
2kceD16Thymidylate synthase/0.479
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.479
3jpuTY4Transcriptional activator protein LasR/0.479
3emlZMAAdenosine receptor A2a/0.479
1h35R01Squalene--hopene cyclase4.2.1.1290.478
1jtuLYBThymidylate synthase/0.478
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.478
2dxdANPNucleoside diphosphate kinase2.7.4.60.478
2rqfJH3Hemolymph juvenile hormone binding protein/0.478
3ix8TX3Transcriptional activator protein LasR/0.478
4a1oAMZBifunctional purine biosynthesis protein PurH2.1.2.30.478
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.478
1qinGIPLactoylglutathione lyase4.4.1.50.477
1w1vALJChitinase/0.477
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
2hxzH7JCathepsin S3.4.22.270.477
2vd0D27Hematopoietic prostaglandin D synthase/0.477
2ywlFADThioredoxin reductase related protein/0.477
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.477
4h6uACOAlpha-tubulin N-acetyltransferase 1/0.477
3dm6757Beta-secretase 13.4.23.460.476
3k8q22APurine nucleoside phosphorylase2.4.2.10.476
4rrbA3TProbable threonine--tRNA ligase 26.1.1.30.476
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.476
5c4fUPGHisto-blood group ABO system transferase/0.476
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.475
2aouCQAHistamine N-methyltransferase2.1.1.80.475
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.475
3oxk5GPHistidine triad nucleotide-binding protein30.475
3vt45YIVitamin D3 receptor/0.475
4kc1WS1Histo-blood group ABO system transferase/0.475
4x9dU5PUncharacterized protein MJ1435/0.475
1pq944BOxysterols receptor LXR-beta/0.473
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.473
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.473
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.473
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.473
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.473
4ey6GNTAcetylcholinesterase3.1.1.70.473
1e7wMTXPteridine reductase 11.5.1.330.472
1h22E10Acetylcholinesterase3.1.1.70.472
1mvtDTMDihydrofolate reductase1.5.1.30.472
1nceCB3Thymidylate synthase/0.472
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.472
2xlrFADPutative flavin-containing monooxygenase/0.472
3vt3VDXVitamin D3 receptor/0.472
3w0c6DSVitamin D3 receptor/0.472
4eiyZMAAdenosine receptor A2a/0.472
5h8tRTLRetinol-binding protein 1/0.472
5iubCLRAdenosine receptor A2a/0.472
1pd9CO4Dihydrofolate reductase1.5.1.30.471
2fhlBNIAvidin-related protein 4/5/0.471
2jb4A14Isopenicillin N synthase1.21.3.10.471
2op18PCEnoyl-ACP reductase/0.471
2pg0FADAcyl-CoA dehydrogenase/0.471
3fazNOSPurine nucleoside phosphorylase/0.471
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.471
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.471
3zhoFMNNAD(P)H dehydrogenase (quinone)/0.471
4b67NAPL-ornithine N(5)-monooxygenase/0.471
4iteTEYVitamin D3 receptor/0.471
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.471
5c4cUPGHisto-blood group ABO system transferase/0.471
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.470
1pqc444Oxysterols receptor LXR-beta/0.470
1swtBTNStreptavidin/0.470
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.470
2hb7O1CVitamin D3 receptor/0.470
2iqgF2IBeta-secretase 13.4.23.460.470
2v5zSAGAmine oxidase [flavin-containing] B1.4.3.40.470
3dhbC6LN-acyl homoserine lactonase AiiA3.1.1.810.470
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.470
3pd5TSBThreonine--tRNA ligase6.1.1.30.470
3t3r9PLCytochrome P450 2A61.14.130.470
3vtbTKAVitamin D3 receptor/0.470
1zp4C2F5,10-methylenetetrahydrofolate reductase1.5.1.200.469
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
2pswCOAN-alpha-acetyltransferase 50/0.469
2ym2NAPPhenylacetone monooxygenase1.14.13.920.469
2zynBCDPeriplasmic binding protein/0.469
3c3eGDP2-phospho-L-lactate transferase/0.469
3hf8ML0Tryptophan 5-hydroxylase 11.14.16.40.469
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.469
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.469
4ise1FWGlucokinase2.7.1.20.469
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
1bk0ACVIsopenicillin N synthase1.21.3.10.468
1kceCB3Thymidylate synthase/0.468
1opbRETRetinol-binding protein 2/0.468
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.468
1zw9H64ATP-dependent molecular chaperone HSP82/0.468
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
2pnuENMAndrogen receptor/0.468
2vd7PD2Lysine-specific demethylase 4A1.14.110.468
3c1oNAPEugenol synthase/0.468
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
4bfzZVZPantothenate kinase2.7.1.330.468
4cfbOM3Integrase/0.468
1b8oIMHPurine nucleoside phosphorylase2.4.2.10.467
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.467
1kt3RTLRetinol-binding protein 4/0.467
2uywBTNAvd protein/0.467
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.467
4dvi2IWTankyrase-12.4.2.300.467
4gsuDWZL,D-transpeptidase 22.3.20.467
5ig2NADShort-chain dehydrogenase/reductase SDR/0.467
1fkxPRHAdenosine deaminase3.5.4.40.466
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.466
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.466
1q23FUAChloramphenicol acetyltransferase2.3.1.280.466
1trgCB3Thymidylate synthase/0.466
2ociTYCValacyclovir hydrolase3.10.466
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.466
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.466
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.466
3t0kDCQSulfide-quinone reductase/0.466
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.466
4n4v2GYTankyrase-12.4.2.300.466
5iu4ZMAAdenosine receptor A2a/0.466
1xzqFONtRNA modification GTPase MnmE3.6.50.465
2cekN8TAcetylcholinesterase3.1.1.70.465
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.465
2igqSAHHistone-lysine N-methyltransferase EHMT1/0.465
3b82NADExotoxin A2.4.2.360.465
3exfTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.465
3exfTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.465
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.465
3w0yDS4Vitamin D3 receptor/0.465
3wv9FEGHmd co-occurring protein HcgE/0.465
3zpqXF5Beta-1 adrenergic receptor/0.465
4b4vL34Bifunctional protein FolD/0.465
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.465
3vw7VPXProteinase-activated receptor 1/0.465
1mrqSTRAldo-keto reductase family 1 member C1/0.464
1p8dCO1Oxysterols receptor LXR-beta/0.464
1qtiGNTAcetylcholinesterase3.1.1.70.464
1rkhVD2Vitamin D3 receptor/0.464
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.464
1votHUPAcetylcholinesterase3.1.1.70.464
1w6jR71Lanosterol synthase5.4.99.70.464
2hveADPNucleoside diphosphate kinase A2.7.4.60.464
2rs1W84Genome polyprotein/0.464
3c27DKKProthrombin3.4.21.50.464
3c3xNAPEugenol synthase 11.1.1.3180.464
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.464
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.464
3fhxPLPPyridoxal kinase2.7.1.350.464
3ju8NADN-succinylglutamate 5-semialdehyde dehydrogenase1.2.1.710.464
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.464
3tljSAHUncharacterized protein/0.464
3tpr5HABeta-secretase 13.4.23.460.464
4earIM5Purine nucleoside phosphorylase2.4.2.10.464
4gd40WSLysine-specific demethylase 4A1.14.110.464
4pnmNU1Tankyrase-22.4.2.300.464
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.464
4yvnEBSSpore coat protein A/0.464
5kghACOPredicted acetyltransferase/0.464
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.463
1gm8SOXPenicillin G acylase3.5.1.110.463
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.463
2bsxNOSPurine nucleoside phosphorylase/0.463
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.463
2hb8MVDVitamin D3 receptor/0.463
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3kkzSAMUncharacterized protein/0.463
4bueJQFTankyrase-22.4.2.300.463
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.463
5k2dZMAAdenosine receptor A2a/0.463
1me6IVSPlasmepsin-23.4.23.390.462
1qy2IPZMajor urinary protein 1/0.462
1w6rGNTAcetylcholinesterase3.1.1.70.462
2f3eAXQBeta-secretase 13.4.23.460.462
2vcmM11Isopenicillin N synthase1.21.3.10.462
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.462
3ekuCY9Actin-5C/0.462
3h3t16HCollagen type IV alpha-3-binding protein/0.462
3ipq965Oxysterols receptor LXR-alpha/0.462
3mpeN2ACathepsin S3.4.22.270.462
3pm1ETHTH-type transcriptional regulator QacR/0.462
4bj9UHBTankyrase-22.4.2.300.462
1aiqCB3Thymidylate synthase/0.461
1gky5GPGuanylate kinase2.7.4.80.461
1h60STRPentaerythritol tetranitrate reductase/0.461
1mmkH4BPhenylalanine-4-hydroxylase1.14.16.10.461
1uumFMNDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.461
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.461
3h4vDVPPteridine reductase 11.5.1.330.461
3iwjNADAminoaldehyde dehydrogenase/0.461
3n0hTOPDihydrofolate reductase1.5.1.30.461
3rhdNAPLactaldehyde dehydrogenase1.2.1.220.461
3tqcADPPantothenate kinase/0.461
3vi7CBDHematopoietic prostaglandin D synthase/0.461
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.461
4fqsLYAThymidylate synthase ThyA/0.461
4g67SAHUncharacterized ACR, COG1565 superfamily/0.461
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.460
1tilATPAnti-sigma F factor/0.460
2a9z26AAdenosine kinase2.7.1.200.460
2aclL05Oxysterols receptor LXR-alpha/0.460
2j5sKTAAlr4455 protein/0.460
3br3ETHTH-type transcriptional regulator QacR/0.460
3f63GTXGlutathione transferase GST1-4/0.460
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.460
3w0hW12Vitamin D3 receptor/0.460
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
4bcsBTNAvidin-related protein 4/5/0.460
4eqwCOACoenzyme A disulfide reductase/0.460
4psbGA3Cytokinin-specific binding protein/0.460
5k0s0OUMethionine--tRNA ligase/0.460
1f5fDHTSex hormone-binding globulin/0.459
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1j49NADD-lactate dehydrogenase1.1.1.280.459
1n06ADPRiboflavin kinase2.7.1.260.459
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.459
2rm2W43Genome polyprotein/0.459
2xvv9DNSerum albumin/0.459
3csdEMOPutative ketoacyl reductase1.3.10.459
3kslSZHProtein farnesyltransferase subunit beta2.5.1.580.459
3mp5HMGHydroxymethylglutaryl-CoA lyase, mitochondrial4.1.3.40.459
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
3stdMQ0Scytalone dehydratase4.2.1.940.459
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.459
4hwkSFYSepiapterin reductase1.1.1.1530.459
5xraFMNCannabinoid receptor 1/0.459
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.458
1n08ADPRiboflavin kinase2.7.1.260.458
1o6rR19Squalene--hopene cyclase4.2.1.1290.458
1q4xG24Thyroid hormone receptor beta/0.458
1srfMTBStreptavidin/0.458
1xb0ALA_VAL_PRO_ILEBaculoviral IAP repeat-containing protein 8/0.458
1xk9P34Exotoxin A2.4.2.360.458
2acwUPGGlycosyltransferase/0.458
2fziDH3Dihydrofolate reductase1.5.1.30.458
2fznFADBifunctional protein PutA1.5.5.20.458
2p4j23IBeta-secretase 13.4.23.460.458
2rlcCHDCholoylglycine hydrolase3.5.1.240.458
2zevB71Geranylgeranyl pyrophosphate synthase/0.458
3gwdFADCyclohexanone monooxygenase/0.458
3h3r14HCollagen type IV alpha-3-binding protein/0.458
4eilUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.458
4gt8ADPSensor protein VraS2.7.13.30.458
4nqgCZHMitrocomin/0.458
4rr8A3SProbable threonine--tRNA ligase 26.1.1.30.458
4zvmDM2Ribosyldihydronicotinamide dehydrogenase [quinone]/0.458
5ch7MD1DMSO reductase family type II enzyme, molybdopterin subunit/0.458
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.458
5irnADPNucleotide binding oligomerization domain containing 2/0.458
4n4wSNTSmoothened homolog/0.458
1g05BBHStromelysin-13.4.24.170.457
1g8jMGDArsenite oxidase subunit AioA1.20.9.10.457
1kiaSAMGlycine N-methyltransferase2.1.1.200.457
1mvsDTMDihydrofolate reductase1.5.1.30.457
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.457
1rzy5ASHistidine triad nucleotide-binding protein 130.457
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.457
3bgxTMPThymidylate synthase/0.457
3dttNAPNADP oxidoreductase, coenzyme F420-dependent/0.457
3h2sNDPPutative NADH-flavin reductase/0.457
3v0o4GWHisto-blood group ABO system transferase/0.457
4an4DUDPutative glycosyl transferase/0.457
4ieiADPGene 2 protein/0.457
4l7vSAHProtein-L-isoaspartate O-methyltransferase/0.457
4rrdA3TProbable threonine--tRNA ligase 26.1.1.30.457
1fkwPURAdenosine deaminase3.5.4.40.456
1odcA8BAcetylcholinesterase3.1.1.70.456
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.456
1upcTPPN(2)-(2-carboxyethyl)arginine synthase/0.456
2duzZSTAldose reductase1.1.1.210.456
2hq9FADMll6688 protein/0.456
2onmADPAldehyde dehydrogenase, mitochondrial1.2.1.30.456
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
2rhrEMOPutative ketoacyl reductase1.3.10.456
3mauPLRPutative sphingosine-1-phosphate lyase/0.456
3q8uADPNucleoside diphosphate kinase/0.456
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
4cjeQ31Integrase/0.456
4dh60KNBeta-secretase 13.4.23.460.456
4qzuRTLRetinol-binding protein 2/0.456
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.456
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.456
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.455
1swrBTNStreptavidin/0.455
1yw7A41Methionine aminopeptidase 2/0.455
1zgv501Prothrombin3.4.21.50.455
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.455
2p1t3TNRetinoic acid receptor RXR-alpha/0.455
2p5uNADUDP-glucose 4-epimerase/0.455
2xi4AFTAcetylcholinesterase3.1.1.70.455
2z7gEH9Adenosine deaminase3.5.4.40.455
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.455
3junAKDPhenazine biosynthesis protein A/B/0.455
3skgPB8Beta-secretase 13.4.23.460.455
4bz8J38Histone deacetylase/0.455
4eqeKAAHistidine triad nucleotide-binding protein 130.455
4mkhAP5Adenylate kinase/0.455
4q0a4OAVitamin D3 receptor A/0.455
5k0t415Methionine--tRNA ligase/0.455
3d4sTIMBeta-2 adrenergic receptor/0.455
1blzACVIsopenicillin N synthase1.21.3.10.454
1cneFADNitrate reductase [NADH]1.7.1.10.454
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.454
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.454
1rszDIHPurine nucleoside phosphorylase2.4.2.10.454
2qimZEAClass 10 plant pathogenesis-related protein/0.454
2r8vACOAmino-acid acetyltransferase/0.454
2vroNDP3,4-dehydroadipyl-CoA semialdehyde dehydrogenase/0.454
2w6pOA4Biotin carboxylase6.3.4.140.454
2z4y252Geranylgeranyl pyrophosphate synthase/0.454
3djfBC3Purine nucleoside phosphorylase/0.454
3gtsD3MDdmC/0.454
3iexGMPPurine nucleoside phosphorylase/0.454
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.454
3phiNDPShikimate dehydrogenase (NADP(+))/0.454
3qiyQI1Botulinum neurotoxin type A3.4.24.690.454
4at0FADPossible succinate dehydrogenase/0.454
4dpeNGHStromelysin-13.4.24.170.454
4hlf15ZTankyrase-22.4.2.300.454
4iqqD16Thymidylate synthase/0.454
5stdUNNScytalone dehydratase4.2.1.940.454
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.453
1juvNDPDihydrofolate reductase1.5.1.30.453
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.453
1tysDHFThymidylate synthase/0.453
1ut6A8NAcetylcholinesterase3.1.1.70.453
2fb35ADGTP 3',8-cyclase4.1.99.180.453
2fhnBNIAvidin-related protein 4/5/0.453
2g1n1IGRenin3.4.23.150.453
2h2aDNDProbable nicotinate-nucleotide adenylyltransferase/0.453
2hk9NAPShikimate dehydrogenase (NADP(+))/0.453
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
2v13C40Renin3.4.23.150.453
2wdqCBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.453
2wdqCBESuccinate dehydrogenase cytochrome b556 subunit/0.453
2wi4ZZ4Heat shock protein HSP 90-alpha/0.453
2y60M8FIsopenicillin N synthase1.21.3.10.453
3nhlYTRRibosyldihydronicotinamide dehydrogenase [quinone]/0.453
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.453
3vt5YI2Vitamin D3 receptor/0.453
4bb3KKAIsopenicillin N synthase1.21.3.10.453
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4n3r2GUTankyrase-12.4.2.300.453
4rrrA3TThreonine--tRNA ligase6.1.1.30.453
5i2fBS5Histidine triad nucleotide-binding protein 130.453
4mqt2CUMuscarinic acetylcholine receptor M2/0.453
1ef92CPMethylmalonyl-CoA decarboxylase4.1.1.410.452
1nhkCMPNucleoside diphosphate kinase2.7.4.60.452
1pr1FMBPurine nucleoside phosphorylase DeoD-type/0.452
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.452
1rk3VDXVitamin D3 receptor/0.452
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.452
1y52BTNAvidin-related protein 4/5/0.452
2fonFADAcyl-coenzyme A oxidase/0.452
2qhxFE1Pteridine reductase 11.5.1.330.452
3eldSFGMethyltransferase/0.452
3ha5SFGHydroxymycolate synthase MmaA42.1.10.452
3ixp834Ecdysone receptor/0.452
3pd4A3GThreonine--tRNA ligase6.1.1.30.452
3thyADPDNA mismatch repair protein Msh2/0.452
3tl1JROPutative polyketide cyclase/0.452
3w3nRX8Toll-like receptor 8/0.452
3zsxN44Integrase/0.452
3zv7NHGAcetylcholinesterase3.1.1.70.452
4b1e6T6Beta-secretase 13.4.23.460.452
4eqkMGTPolymerase basic protein 2/0.452
4kxjP34Nucleoprotein/0.452
4qbiAP5Adenylate kinase/0.452
1ie8KH1Vitamin D3 receptor/0.451
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.451
1kziTHGThymidylate synthase/0.451
1ra2FOLDihydrofolate reductase1.5.1.30.451
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.451
1yslCOAHydroxymethylglutaryl-CoA synthase2.3.3.100.451
2a9y26AAdenosine kinase2.7.1.200.451
2c29NAPDihydroflavonol 4-reductase/0.451
2gouFMNNADH:flavin oxidoreductase Sye1/0.451
2hizLIJBeta-secretase 13.4.23.460.451
2idkC2FGlycine N-methyltransferase2.1.1.200.451
2iviACWIsopenicillin N synthase1.21.3.10.451
2j3qTFLAcetylcholinesterase3.1.1.70.451
2xuhTZ4Acetylcholinesterase3.1.1.70.451
2zbaZBATrichothecene 3-O-acetyltransferase/0.451
3eksCY9Actin-5C/0.451
3eq02TSProthrombin3.4.21.50.451
3och2MXDihydrofolate reductase1.5.1.30.451
3s3vTOPDihydrofolate reductase1.5.1.30.451
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.451
3zkyWT4Isopenicillin N synthase1.21.3.10.451
4c2jCOA3-ketoacyl-CoA thiolase, mitochondrial2.3.1.160.451
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.451
4ku5DCC3-oxoacyl-[ACP] synthase III/0.451
4rrlA3SProbable threonine--tRNA ligase 26.1.1.30.451
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.451
5czySAMEukaryotic huntingtin interacting protein B/0.451
5eghPCEctonucleotide pyrophosphatase/phosphodiesterase family member 6/0.451
5hbsRTLRetinol-binding protein 1/0.451
1b4pGPSGlutathione S-transferase Mu 2/0.450
1e6zNGOChitinase/0.450
1ivsVAAValine--tRNA ligase6.1.1.90.450
1nm6L86Prothrombin3.4.21.50.450
1v2hGUNPurine nucleoside phosphorylase2.4.2.10.450
1ve3SAMUncharacterized protein/0.450
1zgbA1EAcetylcholinesterase3.1.1.70.450
2bfpH4BPteridine reductase 11.5.1.330.450
2cy2ACOProbable acetyltransferase/0.450
2d81RB3Poly(3-hydroxybutyrate) depolymerase/0.450
2fhjMFNFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.450
2ha6SCKAcetylcholinesterase3.1.1.70.450
2harOCCVitamin D3 receptor/0.450
2x1hX1HProstaglandin reductase 310.450
2xk4OL2Serine/threonine-protein kinase Nek22.7.11.10.450
3a783EVVitamin D3 receptor/0.450
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.450
3exnACOProbable acetyltransferase/0.450
3hf6LX0Tryptophan 5-hydroxylase 11.14.16.40.450
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
3ohh3HHBeta-secretase 13.4.23.460.450
3p0pNNFTankyrase-22.4.2.300.450
3px2T3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.450
3tn7NJPShort-chain alcohol dehydrogenase/0.450
3v0tATRPerakine reductase1.1.1.3170.450
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
3zxhE41Collagenase 33.4.240.450
4cukNAID-lactate dehydrogenase/0.450
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.450
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4j0v1H7Beta-secretase 13.4.23.460.450
4j7uYTZSepiapterin reductase1.1.1.1530.450
4jtqFLPAldo-keto reductase family 1 member C2/0.450
4m6jNDPDihydrofolate reductase1.5.1.30.450
4mprTPPBenzoylformate decarboxylase4.1.1.70.450
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.450
4phlPILPhosphodiesterase/0.450
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
5kgpACOPredicted acetyltransferase/0.450
6stdMS2Scytalone dehydratase4.2.1.940.450
1f28UMPThymidylate synthase2.1.1.450.449
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1jmhUMPThymidylate synthase/0.449
1pk92FAPurine nucleoside phosphorylase DeoD-type/0.449
1qrsATPGlutamine--tRNA ligase6.1.1.180.449
1v7aFRCAdenosine deaminase3.5.4.40.449
1y9r1CAMineralocorticoid receptor/0.449
2bfaCB3Pteridine reductase 11.5.1.330.449
2rtfBTNStreptavidin/0.449
2vfzUPFN-acetyllactosaminide alpha-1,3-galactosyltransferase/0.449
2vk8TPPPyruvate decarboxylase isozyme 1/0.449
2xvw9NRSerum albumin/0.449
2ycnP61Tyrosine phenol-lyase4.1.99.20.449
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.449
3f0aACOSpermidine N(1)-acetyltransferase/0.449
3p9tTCLRepressor/0.449
3pi0F91Endothiapepsin3.4.23.220.449
3w78CBDFMN-dependent NADH-azoreductase/0.449
4a862ANMajor pollen allergen Bet v 1-A/0.449
4esoNAPPutative oxidoreductase/0.449
4ez8DHFThymidylate synthase2.1.1.450.449
4kzl20DTankyrase-22.4.2.300.449
3sn6P0GBeta-2 adrenergic receptor/0.449
1bwlFMNNADPH dehydrogenase 11.6.99.10.448
1eg2MTAModification methylase RsrI2.1.1.720.448
1o5rFR9Adenosine deaminase3.5.4.40.448
1s0xC3SNuclear receptor ROR-alpha/0.448
1s1rNAPAldo-keto reductase family 1 member C3/0.448
1txiTX5Vitamin D3 receptor/0.448
1w2gTHMThymidylate kinase2.7.4.90.448
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2cjfRP43-dehydroquinate dehydratase4.2.1.100.448
2ehuNAD1-pyrroline-5-carboxylate dehydrogenase/0.448
2hamC33Vitamin D3 receptor/0.448
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.448
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.448
2o4rVD5Vitamin D3 receptor/0.448
2ohhFMNType A flavoprotein FprA10.448
2v58LZJBiotin carboxylase6.3.4.140.448
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
3ix3OHNTranscriptional activator protein LasR/0.448
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.448
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
3nu03TUDihydrofolate reductase1.5.1.30.448
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.448
3tydXHPDihydropteroate synthase/0.448
3up5NAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.448
3wyfGTPGTP-binding nuclear protein/0.448
4a8v2ANMajor pollen allergen Bet v 1-J/0.448
4cj4S3GIntegrase/0.448
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.448
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.448
4iae1DXAlr2278 protein/0.448
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.448
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
4y35F90Endothiapepsin3.4.23.220.448
4ys22BAUncharacterized protein/0.448
1bcpATPPertussis toxin subunit 4/0.447
1bcpATPPertussis toxin subunit 5/0.447
1hb1OCVIsopenicillin N synthase1.21.3.10.447
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.447
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.447
1qruATPGlutamine--tRNA ligase6.1.1.180.447
1tysTMPThymidylate synthase/0.447
1yqzCOACoenzyme A disulfide reductase/0.447
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
2bu9HFVIsopenicillin N synthase1.21.3.10.447
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.447
2wwjY28Lysine-specific demethylase 4A/0.447
2xk6EQHSerine/threonine-protein kinase Nek22.7.11.10.447
3biy01KHistone acetyltransferase p300/0.447
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.447
3iwkNADAminoaldehyde dehydrogenase/0.447
3nguADPNucleoside diphosphate kinase/0.447
3v0p4GWHisto-blood group ABO system transferase/0.447
3vruYS3Vitamin D3 receptor/0.447
4bjbP34Tankyrase-22.4.2.300.447
4dmgSAMUncharacterized protein/0.447
4dpi0N1Beta-secretase 13.4.23.460.447
4eqrCOACoenzyme A disulfide reductase/0.447
4i03L88Macrophage metalloelastase3.4.24.650.447
4kc4WS3Histo-blood group ABO system transferase/0.447
4na4A1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.447
4pkwGM6Lethal factor3.4.24.830.447
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.447
4u7wNDPMxaA/0.447
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.447
5eccNAPDehydrofolate reductase type I/0.447
5jadFB2Platelet-activating factor acetylhydrolase3.1.1.470.447
1akeAP5Adenylate kinase/0.446
1ie9VDXVitamin D3 receptor/0.446
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.446
1kkq471Peroxisome proliferator-activated receptor alpha/0.446
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.446
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.446
1pw6FRBInterleukin-2/0.446
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.446
1u65CP0Acetylcholinesterase3.1.1.70.446
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.446
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.446
2on6IMHPurine nucleoside phosphorylase2.4.2.10.446
2ozrGG1Collagenase 33.4.240.446
2uuk897Prothrombin3.4.21.50.446
2vq7NAPPutative flavin-containing monooxygenase/0.446
2x9dITCTetracycline repressor protein class D/0.446
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
3i0pNADMalate dehydrogenase, putative/0.446
3i2834NBifunctional epoxide hydrolase 23.3.2.100.446
3ijdC2FMethylenetetrahydrofolate reductase/0.446
3nxoD2BDihydrofolate reductase1.5.1.30.446
3qgzADNHistidine triad nucleotide-binding protein 130.446
4h0vNADIota toxin component Ia/0.446
4ja1NGHStromelysin-13.4.24.170.446
4jxrACOAcetyltransferase/0.446
4ki0ANPMaltose/maltodextrin import ATP-binding protein MalK/0.446
4l321VFTankyrase-22.4.2.300.446
4l4xNDPAmphI/0.446
4lzwTHMUridine phosphorylase/0.446
4pnrG18Tankyrase-22.4.2.300.446
4pzrCOAHistone acetyltransferase p300/0.446
4zobLGCLin1840 protein/0.446
5bt42LOBromodomain-containing protein 4/0.446
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.446
1dx6GNTAcetylcholinesterase3.1.1.70.445
1e66HUXAcetylcholinesterase3.1.1.70.445
1fxvPNNPenicillin G acylase3.5.1.110.445
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1gssLEEGlutathione S-transferase P2.5.1.180.445
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.445
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.445
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.445
1rjkVDZVitamin D3 receptor/0.445
1x8lOXRRetinol dehydratase/0.445
1zdwFLVPrenyltransferase/0.445
2bglNAJSecoisolariciresinol dehydrogenase1.1.1.3310.445
2flhZEACytokinin-specific binding protein/0.445
2hdjNDPAldo-keto reductase family 1 member C2/0.445
2vbpVB1Isopenicillin N synthase1.21.3.10.445
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.445
3e23SAMUncharacterized protein/0.445
3gkjHC3Niemann-Pick C1 protein/0.445
3klbFMNUncharacterized protein/0.445
3kxoKXOHematopoietic prostaglandin D synthase/0.445
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.445
3nn6HNK6-hydroxy-L-nicotine oxidase/0.445
3u9y09LTankyrase-22.4.2.300.445
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.445
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.445
4c72TLG3-oxoacyl-ACP synthase/0.445
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.445
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.445
4jva1ORcAMP-dependent protein kinase type II-beta regulatory subunit/0.445
4n3l2FNProthrombin3.4.21.50.445
4oztP1AEcdysone receptor, putative/0.445
4tjy3GNTankyrase-22.4.2.300.445
4ytnFD8Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial/0.445
4ytnFD8Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial/0.445
4ytnFD8Succinate dehydrogenase cytochrome b560/0.445
4z24FADPutative GMC-type oxidoreductase R13510.445
5jqhCAUBeta-2 adrenergic receptor/0.445
1gaxVAAValine--tRNA ligase6.1.1.90.444
1kwcBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.444
1pq6965Oxysterols receptor LXR-beta/0.444
1rj6AZMCarbonic anhydrase 144.2.1.10.444
1w6hTITPlasmepsin-23.4.23.390.444
1x1cSAHC-20 methyltransferase/0.444
1xe65FPPlasmepsin-23.4.23.390.444
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.444
2bjhFERFeruloyl esterase A3.1.1.730.444
2cdaNAPGlucose 1-dehydrogenase/0.444
2d1nFA4Collagenase 33.4.240.444
2ibwCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.444
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.444
2xjc5GPCytosolic purine 5'-nucleotidase3.1.3.50.444
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.444
3d7zGK5Mitogen-activated protein kinase 14/0.444
3dd0EZLCarbonic anhydrase 24.2.1.10.444
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.444
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.444
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.444
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.444
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.444
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3ll9ADPIsopentenyl phosphate kinase/0.444
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3p9kCIYCaffeic acid O-methyltransferase/0.444
3pchCHBProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.444
3pqbVGPPutative oxidoreductase/0.444
3px3T3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.444
3tm4SAMUncharacterized protein/0.444
4bb2STRCorticosteroid-binding globulin/0.444
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4dc1NDPPutative ketoacyl reductase1.3.10.444
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.444
4ey7E20Acetylcholinesterase3.1.1.70.444
4g9lNGHStromelysin-13.4.24.170.444
4j0t6T9Beta-secretase 13.4.23.460.444
4jyzATPGlutamine--tRNA ligase6.1.1.180.444
4l091URTankyrase-22.4.2.300.444
4l33F70Tankyrase-22.4.2.300.444
4lxk1YTBeta-secretase 13.4.23.460.444
4rgsV55Repressor protein/0.444
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.444
5c3aURMHisto-blood group ABO system transferase/0.444
1b8nIMGPurine nucleoside phosphorylase2.4.2.10.443
1cizDPSStromelysin-13.4.24.170.443
1el4CTZObelin/0.443
1ex75GPGuanylate kinase2.7.4.80.443
1i2bNADUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.443
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1mv8GDXGDP-mannose 6-dehydrogenase1.1.1.1320.443
1p0pBCHCholinesterase3.1.1.80.443
1p4aPCPPur operon repressor/0.443
1rpnNDPGDP-mannose 4,6-dehydratase/0.443
1s0zEB1Vitamin D3 receptor/0.443
1s63778Protein farnesyltransferase subunit beta2.5.1.580.443
1tj0FADBifunctional protein PutA1.5.5.20.443
1tkbN1TTransketolase 12.2.1.10.443
1vf2GTXGlutathione S-transferase 32.5.1.180.443
2fj1CTCTetracycline repressor protein class D/0.443
2ibuCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.443
2pmdGNPTranslation initiation factor 2 subunit gamma/0.443
2rtmIMIStreptavidin/0.443
2w3bNDPDihydrofolate reductase1.5.1.30.443
2wejFB2Carbonic anhydrase 24.2.1.10.443
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
3bj8COADiamine acetyltransferase 1/0.443
3cjtSAHRibosomal protein L11 methyltransferase2.1.10.443
3k7mFAD6-hydroxy-L-nicotine oxidase/0.443
3lpiZ74Beta-secretase 13.4.23.460.443
3nrcTCLEnoyl-[acyl-carrier-protein] reductase [NADH]/0.443
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.443
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.443
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.443
3q9bB3NAcetylpolyamine amidohydrolase/0.443
3rimTPPTransketolase2.2.1.10.443
3rl45GPMetallophosphoesterase MPPED23.10.443
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.443
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.443
4cfdS8YIntegrase/0.443
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
4f0e0RUPoly [ADP-ribose] polymerase 152.4.2.300.443
4jtqNAPAldo-keto reductase family 1 member C2/0.443
4ttiFMCPurine nucleoside phosphorylase DeoD-type/0.443
4y1bNAPAntE/0.443
4y3qF02Endothiapepsin3.4.23.220.443
5p2pDHGPhospholipase A2, major isoenzyme3.1.1.40.443
1amoFADNADPH--cytochrome P450 reductase/0.442
1cs4FOKAdenylate cyclase type 2/0.442
1cs4FOKAdenylate cyclase type 5/0.442
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.442
1f3lSAHProtein arginine N-methyltransferase 3/0.442
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.442
1if6FBUCarbonic anhydrase 24.2.1.10.442
1mmaADPMyosin-2 heavy chain/0.442
1muuGDXGDP-mannose 6-dehydrogenase1.1.1.1320.442
1o01NADAldehyde dehydrogenase, mitochondrial1.2.1.30.442
1pd8CO4Dihydrofolate reductase1.5.1.30.442
1qg0FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.442
1qjfACSIsopenicillin N synthase1.21.3.10.442
1qvuPRLHTH-type transcriptional regulator QacR/0.442
1s3uTQDDihydrofolate reductase1.5.1.30.442
1tv5A26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.442
1xs7MMIBeta-secretase 13.4.23.460.442
2amb17HAndrogen receptor/0.442
2c12FADNitroalkane oxidase1.7.3.10.442
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.442
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.442
2hcdBIVVitamin D3 receptor A/0.442
2v0uFMNNPH1-1/0.442
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.442
2vqzMGTPolymerase basic protein 2/0.442
2wn6NDPADP-ribosyltransferase enzymatic component/0.442
2xk3XK3Serine/threonine-protein kinase Nek22.7.11.10.442
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.442
3dufR1TPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.442
3dufR1TPyruvate dehydrogenase E1 component subunit beta1.2.4.10.442
3iaaTYDCalG2/0.442
3oafOAGDihydrofolate reductase1.5.1.30.442
3ogwIMNLactoperoxidase1.11.1.70.442
3q43D66M1 family aminopeptidase3.4.110.442
3qm4PN0Cytochrome P450 2D6/0.442
3vrtYS2Vitamin D3 receptor/0.442
3vt7VDXVitamin D3 receptor/0.442
3w5tLHPVitamin D3 receptor/0.442
3w6hAZMCarbonic anhydrase 14.2.1.10.442
3zoiM2WIsopenicillin N synthase1.21.3.10.442
4aoxFADSteroid monooxygenase/0.442
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.442
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.442
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
4dhyS41Glucokinase2.7.1.20.442
4fco0U4Beta-secretase 13.4.23.460.442
4g20484Vitamin D3 receptor A/0.442
4iarERM5-hydroxytryptamine receptor 1B/0.442
4j7hTRHPCZA361.3/0.442
4jq2SUZAldo-keto reductase family 1 member C2/0.442
4jtrIZPAldo-keto reductase family 1 member C2/0.442
4la7A1OAbscisic acid receptor PYL2/0.442
4lsjLSJGlucocorticoid receptor/0.442
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.442
4tm0NAPKtzI/0.442
4wevSUZAldo-keto reductase family 1 member B101.1.10.442
5agyGTBTau class glutathione S-transferase/0.442
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.442
5jhnSAMHistone-lysine N-methyltransferase EHMT2/0.442
5k2aZMAAdenosine receptor A2a/0.442
1e92HBIPteridine reductase 11.5.1.330.441
1ej3CZHAequorin-2/0.441
1ekoI84Aldose reductase1.1.1.210.441
1g63FMNEpidermin decarboxylase4.1.10.441
1gtrATPGlutamine--tRNA ligase6.1.1.180.441
1hfqMOTDihydrofolate reductase1.5.1.30.441
1jtqLY3Thymidylate synthase/0.441
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.441
1lf2R37Plasmepsin-23.4.23.390.441
1p4mADPRiboflavin kinase2.7.1.260.441
1r8qAFBCytohesin-2/0.441
1r8qAFBADP-ribosylation factor 1/0.441
1rftPXMPyridoxal kinase2.7.1.350.441
1rxjBNIStreptavidin/0.441
1yhjR6CPyridoxal kinase2.7.1.350.441
2bu7TF3[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.441
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.441
2xuqTZ4Acetylcholinesterase3.1.1.70.441
2zshGA3Gibberellin receptor GID1A30.441
3eem53VUncharacterized protein/0.441
3eigMTXDihydrofolate reductase1.5.1.30.441
3gf4U5PUDP-galactopyranose mutase5.4.99.90.441
3ixk929Beta-secretase 13.4.23.460.441
3pbzF02Endothiapepsin3.4.23.220.441
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.441
3w3zGTPGTP-binding nuclear protein Ran/0.441
3w8fNAD3-hydroxybutyrate dehydrogenase/0.441
3wypBSOStreptavidin/0.441
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.441
4avwG18Tankyrase-22.4.2.300.441
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.441
4b8zNAPGDP-L-fucose synthase1.1.1.2710.441
4bfvZVVPantothenate kinase2.7.1.330.441
4biwANPSensor histidine kinase CpxA/0.441
4buxF35Tankyrase-22.4.2.300.441
4cf1IY7Integrase/0.441
4hlh20DTankyrase-22.4.2.300.441
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.441
4o71CPBBromodomain-containing protein 4/0.441
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.441
4rh10TTSpore photoproduct lyase/0.441
4w6z8IDAlcohol dehydrogenase 11.1.1.10.441
4wbdADPPutative cysteine ligase BshC/0.441
7catNDPCatalase1.11.1.60.441
1dhfFOLDihydrofolate reductase1.5.1.30.440
1efaNPFLactose operon repressor/0.440
1f20NAPNitric oxide synthase, brain1.14.13.390.440
1f9aATPNicotinamide-nucleotide adenylyltransferase/0.440
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
1j8uH4BPhenylalanine-4-hydroxylase1.14.16.10.440
1s36CEIObelin/0.440
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.440
2f3815MAldo-keto reductase family 1 member C3/0.440
2fszOHTEstrogen receptor beta/0.440
2gvdFKPAdenylate cyclase type 2/0.440
2gvdFKPAdenylate cyclase type 5/0.440
2v59LZKBiotin carboxylase6.3.4.140.440
2wu4HBPAcetylcholinesterase3.1.1.70.440
2y6fM9FIsopenicillin N synthase1.21.3.10.440
2ym1FADPhenylacetone monooxygenase1.14.13.920.440
2zb45OPProstaglandin reductase 21.3.1.480.440
3e39FMNNitroreductase/0.440
3g1lRF2HTH-type transcriptional regulator EthR/0.440
3o6o94MHeat shock protein 83/0.440
3oqkS52Renin3.4.23.150.440
3r7mSUZAldo-keto reductase family 1 member C3/0.440
3s1dZIRCytokinin dehydrogenase 11.5.99.120.440
3tm5SFGUncharacterized protein/0.440
3w5p4OAVitamin D3 receptor/0.440
4a4xJUPSerine/threonine-protein kinase Nek22.7.11.10.440
4a84DXCMajor pollen allergen Bet v 1-A/0.440
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4araC56Acetylcholinesterase3.1.1.70.440
4arbC57Acetylcholinesterase3.1.1.70.440
4b7zQ4QAcetylcholinesterase3.1.1.70.440
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.440
4chyC5QIntegrase/0.440
4fhi0S4Vitamin D3 receptor A/0.440
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4gtm7TMProtein farnesyltransferase subunit beta2.5.1.580.440
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.440
4k0tD9ZCarbonic anhydrase 24.2.1.10.440
4l1xNAPAldo-keto reductase family 1 member C2/0.440
4m9aFDAAcyl-CoA dehydrogenase/0.440
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.440
4nh82LCHeat shock protein HSP 90-alpha/0.440