sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5cx6	CDP	RNA-dependent RNA polymerase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
5cx6	CDP	RNA-dependent RNA polymerase	/	1.000
3e2s	FAD	Bifunctional protein PutA	1.5.5.2	0.464
2wlg	SOP	Polysialic acid O-acetyltransferase	/	0.462
2a8x	FAD	Dihydrolipoyl dehydrogenase	1.8.1.4	0.455
2pc4	ASP_TRP_ASN	Fructose-bisphosphate aldolase	4.1.2.13	0.451
3n7u	NAD	Formate dehydrogenase, chloroplastic/mitochondrial	/	0.451
5av3	KMP	Death-associated protein kinase 1	2.7.11.1	0.451
3i4b	Z48	Glycogen synthase kinase-3 beta	2.7.11.26	0.444
2nua	COA	Succinate--CoA ligase [ADP-forming] subunit alpha	6.2.1.5	0.443
2c3q	GTX	Glutathione S-transferase theta-1	2.5.1.18	0.441
1jkl	ANP	Death-associated protein kinase 1	2.7.11.1	0.440