sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5ch7	MGD	DMSO reductase family type II enzyme, molybdopterin subunit

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
5ch7	MGD	DMSO reductase family type II enzyme, molybdopterin subunit	/	1.000
4ydd	MGD	DMSO reductase family type II enzyme, molybdopterin subunit	/	0.586
5e7o	MGD	DMSO reductase family type II enzyme, molybdopterin subunit	/	0.527
4q71	FAD	Bifunctional protein PutA	/	0.458
3kyb	FAD	UDP-galactopyranose mutase	5.4.99.9	0.453
3qwb	NDP	Probable quinone oxidoreductase	1.6.5.5	0.449
3nxx	NDP	Dihydrofolate reductase	1.5.1.3	0.448
3zuy	TCH	Transporter	/	0.447
1g0n	NDP	Tetrahydroxynaphthalene reductase	1.1.1.252	0.446
2zs9	ADP	Pantothenate kinase	2.7.1.33	0.445
3bhi	NAP	Carbonyl reductase [NADPH] 1	1.1.1.184	0.444
3dme	FAD	Putative conserved exported protein	/	0.443
2vkm	BSD	Beta-secretase 1	3.4.23.46	0.440
4fco	0U4	Beta-secretase 1	3.4.23.46	0.440