sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5ccb	SAH	tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A	2.1.1.220

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
5ccb	SAH	tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A	2.1.1.220	1.000
1i9g	SAM	tRNA (adenine(58)-N(1))-methyltransferase TrmI	/	0.503
5ccx	SAH	tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A	2.1.1.220	0.500
3lga	SAH	tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase TrmI	2.1.1.219	0.446
3lhd	SAH	tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase TrmI	2.1.1.219	0.443