sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5c4f | UPG | Histo-blood group ABO system transferase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 1.000 | |
| 5c4c | UPG | Histo-blood group ABO system transferase | / | 0.566 | |
| 5c47 | URM | Histo-blood group ABO system transferase | / | 0.507 | |
| 5c1l | GDU | Histo-blood group ABO system transferase | / | 0.485 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.462 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.448 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.448 | |
| 1zdw | FLV | Prenyltransferase | / | 0.447 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.447 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.443 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.442 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.440 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.440 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.440 |