sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5c3c | ADP | CbbQ/NirQ/NorQ domain protein |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5c3c | ADP | CbbQ/NirQ/NorQ domain protein | / | 1.000 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.470 | |
| 1rbm | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.467 | |
| 3p8z | 36A | Genome polyprotein | 2.1.1.56 | 0.457 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3a7h | ATP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.452 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.451 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 4l9q | 9TP | Serum albumin | / | 0.449 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.449 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.448 | |
| 2p41 | SAH | Genome polyprotein | / | 0.446 | |
| 2w4i | VGA | Glutamate racemase | / | 0.446 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.445 | |
| 1uof | PNN | Deacetoxycephalosporin C synthase | 1.14.20.1 | 0.445 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.444 | |
| 1z1f | STL | Resveratrol synthase | / | 0.444 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.444 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.443 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.443 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.441 | |
| 1dq8 | COA | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.440 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.440 | |
| 2wle | COA | Polysialic acid O-acetyltransferase | / | 0.440 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.440 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.440 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.440 |