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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/1.000
5c3jFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.634
4ytnFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.614
4kx6FADFumarate reductase flavoprotein subunit1.3.5.40.586
1kf6FADFumarate reductase flavoprotein subunit1.3.5.40.559
3sfeFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.554
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.520
1d4cFADFumarate reductase flavoprotein subunit1.3.5.40.468
2du8FADD-amino-acid oxidase1.4.3.30.467
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.456
2rgoFADAlpha-Glycerophosphate Oxidase/0.453
3ctyFADProbable thioredoxin reductase/0.452
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.449
2fjbSFDAdenylylsulfate reductase, subunit A (AprA)/0.446
1f0xFADD-lactate dehydrogenase1.1.1.280.444
2gh5FADGlutathione reductase, mitochondrial1.8.1.70.442