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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5ayaX8ZMetallo-beta-lactamase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5ayaX8ZMetallo-beta-lactamase/1.000
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.471
4q0kGA3Phytohormone-binding protein/0.454
4ramPNMMetallo-beta-lactamase type 2/0.448
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.443
4bgg844Activin receptor type-12.7.11.300.442