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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5ai5BSUBifunctional epoxide hydrolase 23.1.3.76

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5ai5BSUBifunctional epoxide hydrolase 23.1.3.761.000
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.589
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.588
4jnc1LFBifunctional epoxide hydrolase 23.1.3.760.585
4haiI23Bifunctional epoxide hydrolase 23.1.3.760.575
3antS82Bifunctional epoxide hydrolase 23.3.2.100.565
3koo24DBifunctional epoxide hydrolase 23.3.2.100.565
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.554
3otqMZLBifunctional epoxide hydrolase 23.3.2.100.532
1ek2CDUBifunctional epoxide hydrolase 2/0.475
1blzACVIsopenicillin N synthase1.21.3.10.445
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.445