sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4zqc	F6F	Tryptophan synthase alpha chain

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4zqc	F6F	Tryptophan synthase alpha chain	/	1.000
4wx2	F6F	Tryptophan synthase alpha chain	/	0.546
4wx2	F6F	Tryptophan synthase beta chain	4.2.1.20	0.546
4y6g	F6F	Tryptophan synthase alpha chain	/	0.533
1k7f	IAV	Tryptophan synthase alpha chain	/	0.528
2cle	F6F	Tryptophan synthase alpha chain	/	0.492
1qoq	IGP	Tryptophan synthase alpha chain	/	0.468
1kfb	IGP	Tryptophan synthase alpha chain	/	0.450
1k8z	IAG	Tryptophan synthase alpha chain	/	0.446
2clf	F6F	Tryptophan synthase alpha chain	/	0.444