sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4yus | FMN | Family 3 adenylate cyclase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4yus | FMN | Family 3 adenylate cyclase | / | 1.000 | |
| 1x0p | FAD | Tll0078 protein | / | 0.565 | |
| 4hh0 | FMN | AppA protein | / | 0.529 | |
| 2iyi | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.502 | |
| 1yrx | FMN | AppA protein | / | 0.500 | |
| 2iyg | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.493 | |
| 2hfn | FMN | Activator of photopigment and puc expression | / | 0.484 | |
| 3gfz | FMN | Uncharacterized protein | / | 0.472 | |
| 3gfy | FMN | Uncharacterized protein | / | 0.463 | |
| 3gg1 | FMN | Uncharacterized protein | / | 0.461 | |
| 3gfx | FMN | Uncharacterized protein | / | 0.459 | |
| 3gg0 | FMN | Uncharacterized protein | / | 0.459 | |
| 2byc | FMN | Blue-light receptor of the BLUF-family | / | 0.456 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.454 | |
| 4yut | FMN | Family 3 adenylate cyclase | / | 0.452 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.448 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.446 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3rbv | NAP | Sugar 3-ketoreductase | / | 0.444 | |
| 1f20 | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 2vwh | NAP | Glucose 1-dehydrogenase | / | 0.440 |