sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4xvr | GNP | GTPase HRas |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4xvr | GNP | GTPase HRas | / | 1.000 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.560 | |
| 4xvq | GNP | GTPase HRas | / | 0.537 | |
| 2rgg | GNP | GTPase HRas | / | 0.534 | |
| 3tgp | GNP | GTPase HRas | / | 0.529 | |
| 4hdq | GNP | Ras-related protein Rap-1b | / | 0.523 | |
| 1lfd | GNP | GTPase HRas | / | 0.521 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.499 | |
| 4tq9 | GDP | GTPase KRas | / | 0.476 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.473 | |
| 3ddc | GNP | GTPase HRas | / | 0.469 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.465 | |
| 2c5l | GTP | GTPase HRas | / | 0.457 | |
| 2rge | GNP | GTPase HRas | / | 0.454 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.452 | |
| 3kkq | GDP | Ras-related protein M-Ras | / | 0.451 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.451 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.450 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.449 | |
| 4epw | GDP | GTPase KRas | / | 0.449 | |
| 4lpk | GDP | GTPase KRas | / | 0.449 | |
| 2cl6 | CAG | GTPase HRas | / | 0.448 | |
| 3oiv | GNP | GTPase HRas | / | 0.447 | |
| 3v4f | GNP | GTPase HRas | / | 0.440 |