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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4xugF9FTryptophan synthase alpha chain

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4xugF9FTryptophan synthase alpha chain/1.000
1a5sFIPTryptophan synthase alpha chain/0.680
2clhF19Tryptophan synthase alpha chain/0.674
2clfF6FTryptophan synthase alpha chain/0.639
1a50FIPTryptophan synthase alpha chain/0.635
2trsIPLTryptophan synthase alpha chain/0.626
1fuyFIPTryptophan synthase alpha chain/0.597
1k8zIAGTryptophan synthase alpha chain/0.585
2cleF6FTryptophan synthase alpha chain/0.571
1kfbIGPTryptophan synthase alpha chain/0.565
1k8y13PTryptophan synthase alpha chain/0.549
4y6gF6FTryptophan synthase alpha chain/0.545
2rh9IGPTryptophan synthase alpha chain/0.535
2rhgIGPTryptophan synthase alpha chain/0.524
1qoqIGPTryptophan synthase alpha chain/0.523
1kfcIPLTryptophan synthase alpha chain/0.514
1bifAGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.509
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.506
1zdwFLVPrenyltransferase/0.504
1olmVTQSEC14-like protein 2/0.502
1u0wSTLChalcone synthase 22.3.1.740.502
2mm3CHOGastrotropin/0.502
3pqbVGPPutative oxidoreductase/0.498
1a5bIGPTryptophan synthase alpha chain/0.497
3c3dFO12-phospho-L-lactate transferase/0.497
2a84ATPPantothenate synthetase6.3.2.10.496
1fmjRTLRetinol dehydratase/0.495
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.494
4n1gCEIObelin/0.493
2amb17HAndrogen receptor/0.492
3b9lAZZSerum albumin/0.492
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.492
4tlaADPCircadian clock protein kinase KaiC2.7.11.10.491
1b2lNDCAlcohol dehydrogenase1.1.1.10.490
4kugNAD3-hydroxybutyryl-CoA dehydrogenase/0.490
2ij7TPFMycocyclosin synthase1.14.21.90.488
3iktNADRedox-sensing transcriptional repressor Rex/0.488
3e5hGNPRas-related protein Rab-28/0.487
3h3t16HCollagen type IV alpha-3-binding protein/0.487
1rsgFADPolyamine oxidase FMS1/0.486
2cbrA80Cellular retinoic acid-binding protein 1/0.486
2yhuWHFPteridine reductase/0.485
3br3ETHTH-type transcriptional regulator QacR/0.485
3ewrAPRReplicase polyprotein 1a3.4.220.485
3zrrPXGSerine-pyruvate aminotransferase (AgxT)/0.485
1s7gNADNAD-dependent protein deacylase 2/0.484
2xvq9DSSerum albumin/0.484
1crbRTLRetinol-binding protein 1/0.483
1p0hACOMycothiol acetyltransferase2.3.1.1890.483
3i6rJ5ZDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.483
3zqtTESAndrogen receptor/0.483
4an4DUDPutative glycosyl transferase/0.483
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.483
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
3p0fBAUUridine phosphorylase 22.4.2.30.482
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.482
3vev0H4Glucokinase2.7.1.20.482
4a5lNDPThioredoxin reductase/0.482
4la7A1OAbscisic acid receptor PYL2/0.482
1kmsLIHDihydrofolate reductase1.5.1.30.481
4li81XQTankyrase-12.4.2.300.481
4rh10TTSpore photoproduct lyase/0.481
2yloTESAndrogen receptor/0.480
2zevB71Geranylgeranyl pyrophosphate synthase/0.480
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.480
4eqrCOACoenzyme A disulfide reductase/0.480
4fhf0TTSpore photoproduct lyase/0.480
4twnB96Ephrin type-A receptor 32.7.10.10.480
1yqzCOACoenzyme A disulfide reductase/0.479
2q59240Peroxisome proliferator-activated receptor gamma/0.479
2vcmM11Isopenicillin N synthase1.21.3.10.479
3fhxPLPPyridoxal kinase2.7.1.350.479
4g8bHL6Alpha/beta hydrolase fold protein/0.479
4wx2F6FTryptophan synthase alpha chain/0.479
4wx2F6FTryptophan synthase beta chain4.2.1.200.479
5h8tRTLRetinol-binding protein 1/0.479
1beuIPLTryptophan synthase alpha chain/0.478
1e2nRCAThymidine kinase/0.478
2op18PCEnoyl-ACP reductase/0.478
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.477
2c27ACOMycothiol acetyltransferase2.3.1.1890.477
2q153MRBeta-secretase 13.4.23.460.477
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.477
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.477
1kqgMGDFormate dehydrogenase, nitrate-inducible, major subunit1.1.5.60.476
2fzhDH1Dihydrofolate reductase1.5.1.30.476
3cseN22Uncharacterized protein/0.476
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.476
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.476
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.476
3qakUKAAdenosine receptor A2a/0.476
1upw444Oxysterols receptor LXR-beta/0.475
2aclL05Oxysterols receptor LXR-alpha/0.475
2xvv9DNSerum albumin/0.475
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.475
4az3S35Lysosomal protective protein3.4.16.50.475
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.475
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
3gc52MQQueuine tRNA-ribosyltransferase2.4.2.290.474
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.473
2rlcCHDCholoylglycine hydrolase3.5.1.240.473
2znnS44Peroxisome proliferator-activated receptor alpha/0.473
3ih0ANPUncharacterized sugar kinase PH14592.7.10.473
3k47D09Dihydrofolate reductase1.5.1.30.473
3qfaFADThioredoxin reductase 1, cytoplasmic1.8.1.90.473
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
4hlh20DTankyrase-22.4.2.300.473
1hvyD16Thymidylate synthase2.1.1.450.472
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.472
1t91GTPRas-related protein Rab-7a/0.472
1u1f183Uridine phosphorylase2.4.2.30.472
1uzwCDHIsopenicillin N synthase1.21.3.10.472
3akn11DFatty acid-binding protein, intestinal/0.472
3pm1ETHTH-type transcriptional regulator QacR/0.472
3uayADNPurine nucleoside phosphorylase DeoD-type/0.472
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.472
4oztP1AEcdysone receptor, putative/0.472
4pnmNU1Tankyrase-22.4.2.300.472
1jqiFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.471
1lkdBP6Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.471
1stdBFSScytalone dehydratase4.2.1.940.471
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3jziJZLBiotin carboxylase6.3.4.140.471
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3njoPYVAbscisic acid receptor PYR1/0.471
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.471
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.471
2fpcSCGStrictosidine synthase4.3.3.20.470
3i68J4ZDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.470
4bus32FTankyrase-22.4.2.300.470
4k9yK9YFocal adhesion kinase 12.7.10.20.470
1aqv0HGGlutathione S-transferase P2.5.1.180.469
1itzTPPTransketolase, chloroplastic2.2.1.10.469
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.469
2fziDH3Dihydrofolate reductase1.5.1.30.469
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.469
2q7kTESAndrogen receptor/0.469
3dr1C5DVitamin D3 receptor A/0.469
3gncQQQGlutaryl-CoA dehydrogenase/0.469
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
4h380YXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.469
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.468
2hxzH7JCathepsin S3.4.22.270.468
3gwnFADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.468
3zlmANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.468
4bfvZVVPantothenate kinase2.7.1.330.468
4eqsCOACoenzyme A disulfide reductase/0.468
4hlf15ZTankyrase-22.4.2.300.468
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.468
1bygSTUTyrosine-protein kinase CSK/0.467
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.467
1muuGDXGDP-mannose 6-dehydrogenase1.1.1.1320.467
1mv8GDXGDP-mannose 6-dehydrogenase1.1.1.1320.467
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.467
2j7cIDEBeta-glucosidase A3.2.1.210.467
2pb6SAHDiphthine synthase/0.467
2wu4HBPAcetylcholinesterase3.1.1.70.467
3mbgFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.467
3n4mCMPcAMP-activated global transcriptional regulator CRP/0.467
3u5sFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.467
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.467
4l5b1UXDeoxycytidine kinase2.7.1.740.467
2a9y26AAdenosine kinase2.7.1.200.466
2w3mFOLDihydrofolate reductase1.5.1.30.466
2xwyIB8Genome polyprotein2.7.7.480.466
3jq8DX3Pteridine reductase, putative/0.466
3r5yF42Uncharacterized protein/0.466
4a802ANMajor pollen allergen Bet v 1-A/0.466
4b4w9L9Bifunctional protein FolD/0.466
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.466
4eji0QACytochrome P450 2A131.14.14.10.466
4i9i1DYTankyrase-12.4.2.300.466
4kzl20DTankyrase-22.4.2.300.466
4l2f1V3Tankyrase-22.4.2.300.466
1mfzGDXGDP-mannose 6-dehydrogenase1.1.1.1320.465
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.465
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.465
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.465
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
4l0v1V1Tankyrase-22.4.2.300.465
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.465
2ftoCB3Thymidylate synthase/0.464
2gbyBRNHTH-type transcriptional regulator QacR/0.464
2gjlFMNNitronate monooxygenase1.13.12.160.464
2zbaZBATrichothecene 3-O-acetyltransferase/0.464
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.464
3uptTPPTransketolase/0.464
4gcxPRFQueuine tRNA-ribosyltransferase2.4.2.290.464
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.464
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.464
4tlbAGSCircadian clock protein kinase KaiC2.7.11.10.464
3emlZMAAdenosine receptor A2a/0.464
1fm6BRLPeroxisome proliferator-activated receptor gamma/0.463
1ie8KH1Vitamin D3 receptor/0.463
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
1pr0NOSPurine nucleoside phosphorylase DeoD-type/0.463
1t7o152Carnitine O-acetyltransferase2.3.1.70.463
2pobGW4Peroxisome proliferator-activated receptor gamma/0.463
2wjoQUDBeta-secretase 13.4.23.460.463
3m0oFADMonomeric sarcosine oxidase1.5.3.10.463
3p9tTCLRepressor/0.463
3q8hAO92-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.463
3v4eCOAPutative acetyltransferase SACOL25702.3.10.463
3vruYS3Vitamin D3 receptor/0.463
4ele31IDihydrofolate reductase/0.463
4p9dTMPDeoxycytidylate deaminase/0.463
4q71FADBifunctional protein PutA/0.463
5ab6CAANonspecific lipid-transfer protein, putative/0.463
1e7aPFLSerum albumin/0.462
1xddAAYIntegrin alpha-L/0.462
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.462
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.462
3gyf51PDihydrofolate reductase1.5.1.30.462
3hv3R49Mitogen-activated protein kinase 14/0.462
3otwCOAPhosphopantetheine adenylyltransferase/0.462
4b4vL34Bifunctional protein FolD/0.462
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.462
4caxMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.462
4i521HA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.462
4kak06UDihydrofolate reductase1.5.1.30.462
5epvACPBlue-light-activated histidine kinase2.7.13.30.462
5hbsRTLRetinol-binding protein 1/0.462
1jtuLYBThymidylate synthase/0.461
1l0lFMXCytochrome b/0.461
1ppjANYCytochrome b/0.461
1w22NHBHistone deacetylase 83.5.1.980.461
1z4uPH9Polyprotein/0.461
2bdyUNBProthrombin3.4.21.50.461
2pioDHTAndrogen receptor/0.461
2xvw9NRSerum albumin/0.461
2zb3NDPProstaglandin reductase 21.3.1.480.461
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3h3qH13Collagen type IV alpha-3-binding protein/0.461
3mdmFJZCholesterol 24-hydroxylase/0.461
3qly55VUncharacterized protein/0.461
3up3XCAaceDAF-12/0.461
3vf9477Tyrosine-protein kinase SYK2.7.10.20.461
4q0kGA3Phytohormone-binding protein/0.461
4rr8A3SProbable threonine--tRNA ligase 26.1.1.30.461
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
1ia3TQ5Dihydrofolate reductase1.5.1.30.460
1osvCHCBile acid receptor/0.460
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.460
1touB1VFatty acid-binding protein, adipocyte/0.460
2acwUPGGlycosyltransferase/0.460
2bbqPFGThymidylate synthase/0.460
2bjfDXCCholoylglycine hydrolase3.5.1.240.460
2e0nSAHPrecorrin-2 C20-methyltransferase/0.460
2zcePYLPyrrolysine--tRNA ligase/0.460
3d90NOGProgesterone receptor/0.460
3g70A5TRenin3.4.23.150.460
3jzfJZKBiotin carboxylase6.3.4.140.460
3lanKBTGag-Pol polyprotein2.7.7.490.460
3m12FADMonomeric sarcosine oxidase1.5.3.10.460
4afgQMRAchbp/0.460
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.460
4biwANPSensor histidine kinase CpxA/0.460
4emaBRLPeroxisome proliferator-activated receptor gamma/0.460
4hlm16STankyrase-22.4.2.300.460
4hmhF94Tankyrase-22.4.2.300.460
4udaDEXMineralocorticoid receptor/0.460
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.459
1eqbFFOSerine hydroxymethyltransferase2.1.2.10.459
1gky5GPGuanylate kinase2.7.4.80.459
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1trgCB3Thymidylate synthase/0.459
1xzqFONtRNA modification GTPase MnmE3.6.50.459
1zgv501Prothrombin3.4.21.50.459
1zrzBI1Protein kinase C iota type2.7.11.130.459
2clmF6FTryptophan synthase alpha chain/0.459
2mokFMNFlavodoxin 1/0.459
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
2pivDHTAndrogen receptor/0.459
2q7iTESAndrogen receptor/0.459
2zwaSAHtRNA wybutosine-synthesizing protein 42.1.1.2900.459
3e92G6AMitogen-activated protein kinase 14/0.459
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.459
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.459
3lmhADPMyosin heavy chain kinase A2.7.11.70.459
4mlhVO2Glucokinase2.7.1.20.459
4yekTHMThymidine phosphorylase/0.459
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.459
3sn6P0GBeta-2 adrenergic receptor/0.459
1i59ADPChemotaxis protein CheA2.7.13.30.458
1mg5NAIAlcohol dehydrogenase1.1.1.10.458
1rgsCMPcAMP-dependent protein kinase type I-alpha regulatory subunit/0.458
1rzuADPGlycogen synthase 12.4.1.210.458
1v4sMRKGlucokinase2.7.1.20.458
2cjfRP43-dehydroquinate dehydratase4.2.1.100.458
2hw2RFPRifampin ADP-ribosyl transferase/0.458
2pb4SAHDiphthine synthase/0.458
2rhrEMOPutative ketoacyl reductase1.3.10.458
2v58LZJBiotin carboxylase6.3.4.140.458
3dmtNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.458
3gieACPSensor histidine kinase DesK2.7.13.30.458
3kk6CELProstaglandin G/H synthase 11.14.99.10.458
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3n39FMNProtein NrdI/0.458
4cukNAID-lactate dehydrogenase/0.458
4dch4DCGlucokinase2.7.1.20.458
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.458
4obwSAM2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial/0.458
4ofrDHTAndrogen receptor/0.458
4qe6JN3Bile acid receptor/0.458
4tyj0LIFibroblast growth factor receptor 42.7.10.10.458
1dliUDXUDP-glucose 6-dehydrogenase/0.457
1pr5TBNPurine nucleoside phosphorylase DeoD-type/0.457
2aa5STRMineralocorticoid receptor/0.457
2ao6R18Androgen receptor/0.457
2j5sKTAAlr4455 protein/0.457
2q61SF1Peroxisome proliferator-activated receptor gamma/0.457
2q8sL92Peroxisome proliferator-activated receptor gamma/0.457
2rqfJH3Hemolymph juvenile hormone binding protein/0.457
3a783EVVitamin D3 receptor/0.457
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.457
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3oiaA31Camphor 5-monooxygenase1.14.15.10.457
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.457
3w9rA8SAbscisic acid receptor PYL9/0.457
4eh2IRGMitogen-activated protein kinase 14/0.457
4ffrATPUncharacterized protein/0.457
4jva1ORcAMP-dependent protein kinase type II-beta regulatory subunit/0.457
4l3q926Glucokinase2.7.1.20.457
4l8u9AZSerum albumin/0.457
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.457
1dajMOTDihydrofolate reductase1.5.1.30.456
1dg7WRBDihydrofolate reductase1.5.1.30.456
1ie9VDXVitamin D3 receptor/0.456
1opbRETRetinol-binding protein 2/0.456
1rftPXMPyridoxal kinase2.7.1.350.456
1txtCAAHMG-CoA synthase/0.456
2bxqIMNSerum albumin/0.456
2idkC2FGlycine N-methyltransferase2.1.1.200.456
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.456
2qtvGNPSmall COPII coat GTPase SAR13.6.50.456
2vbpVB1Isopenicillin N synthase1.21.3.10.456
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.456
3is9AC7Gag-Pol polyprotein2.7.7.490.456
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.456
3uawADNPurine nucleoside phosphorylase DeoD-type/0.456
3v49PK0Androgen receptor/0.456
3wv9FEGHmd co-occurring protein HcgE/0.456
4c73TLH3-oxoacyl-ACP synthase/0.456
4cf7ADPAdenylate kinase/0.456
4dvi2IWTankyrase-12.4.2.300.456
4em9TCEPeroxisome proliferator-activated receptor gamma/0.456
4gh5NADShort-chain dehydrogenase/reductase SDR/0.456
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.456
4n1fCZHObelin/0.456
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.456
4tl7ATPCircadian clock protein kinase KaiC2.7.11.10.456
5k2aZMAAdenosine receptor A2a/0.456
1e1qADPATP synthase subunit beta, mitochondrial3.6.3.140.455
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.455
1xtsGTPGTP-binding protein Rheb/0.455
1yinCM3Estrogen receptor/0.455
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.455
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.455
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.455
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.455
2piqDHTAndrogen receptor/0.455
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.455
3eljGS7Mitogen-activated protein kinase 82.7.11.240.455
3fwiCAMCamphor 5-monooxygenase1.14.15.10.455
3s41S41Glucokinase2.7.1.20.455
3vt45YIVitamin D3 receptor/0.455
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.455
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.455
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.455
4ia7BIVVitamin D3 receptor A/0.455
4imfSI3N-acetylneuraminate lyase/0.455
4m11MXMProstaglandin G/H synthase 21.14.99.10.455
4omaLCSMethionine gamma-lyase/0.455
4zqcF6FTryptophan synthase alpha chain/0.455
5k7uSAMN6-adenosine-methyltransferase 70 kDa subunit/0.455
5uviZMAAdenosine receptor A2a/0.455
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.454
1jd0AZMCarbonic anhydrase 124.2.1.10.454
1obnASVIsopenicillin N synthase1.21.3.10.454
1pq944BOxysterols receptor LXR-beta/0.454
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.454
1t7fDHTAndrogen receptor/0.454
2dshSAHDiphthine synthase/0.454
2dxwSAHDiphthine synthase/0.454
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.454
2hamC33Vitamin D3 receptor/0.454
2harOCCVitamin D3 receptor/0.454
2pckSAHDiphthine synthase/0.454
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.454
2rewREWPeroxisome proliferator-activated receptor alpha/0.454
2ycnP61Tyrosine phenol-lyase4.1.99.20.454
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.454
3n0hTOPDihydrofolate reductase1.5.1.30.454
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.454
3pg3DG7Mitogen-activated protein kinase 14/0.454
3slkNDPPolyketide synthase extender module 2/0.454
3v1s0LHStrictosidine synthase4.3.3.20.454
3vrwYS5Vitamin D3 receptor/0.454
4dc0NDPPutative ketoacyl reductase1.3.10.454
4ejmNAPPutative zinc-binding dehydrogenase/0.454
4eqwCOACoenzyme A disulfide reductase/0.454
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.454
4pl9ADPEthylene receptor 1/0.454
5jtbZMAAdenosine receptor A2a/0.454
1aoeGW3Dihydrofolate reductase1.5.1.30.453
1h73ANPHomoserine kinase2.7.1.390.453
1l8tADPAminoglycoside 3'-phosphotransferase2.7.1.950.453
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.453
1vg8GNPRas-related protein Rab-7a/0.453
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
1xowR18Androgen receptor/0.453
1zys199Serine/threonine-protein kinase Chk12.7.11.10.453
2aaxPDNMineralocorticoid receptor/0.453
2e08SAHDiphthine synthase/0.453
2ewaSB2Mitogen-activated protein kinase 14/0.453
2fr3REACellular retinoic acid-binding protein 2/0.453
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.453
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.453
2oz6CMPCyclic AMP receptor-like protein/0.453
2wdzNADGalactitol dehydrogenase/0.453
2z4jDHTAndrogen receptor/0.453
3aosJH2Hemolymph juvenile hormone binding protein/0.453
3c35KAIGlutamate receptor ionotropic, kainate 1/0.453
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.453
3fr4F8AFatty acid-binding protein, adipocyte/0.453
3gwfFADCyclohexanone monooxygenase/0.453
3l3rOAGDihydrofolate reductase1.5.1.30.453
3vt3VDXVitamin D3 receptor/0.453
3zuyTCHTransporter/0.453
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.453
4bcsBTNAvidin-related protein 4/5/0.453
4ewqMWLMitogen-activated protein kinase 14/0.453
4fwnAQPPropionate kinase/0.453
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.453
4iteTEYVitamin D3 receptor/0.453
4ixeIXEDihydrofolate reductase1.5.1.30.453
4j7dI31E3 ubiquitin-protein ligase Mdm26.3.20.453
4l341VGTankyrase-22.4.2.300.453
4ea30NNNociceptin receptor/0.453
1a80NDP2,5-diketo-D-gluconic acid reductase A1.1.1.3460.452
1dlrMXADihydrofolate reductase1.5.1.30.452
1k7fIAVTryptophan synthase alpha chain/0.452
1p0pBCHCholinesterase3.1.1.80.452
1pq6965Oxysterols receptor LXR-beta/0.452
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.452
2gjnFMNNitronate monooxygenase1.13.12.160.452
2in6839Wee1-like protein kinase2.7.10.20.452
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.452
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.452
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.452
2qc8ADPGlutamine synthetase6.3.1.20.452
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.452
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.452
3adaNADSubunit alpha of sarocosine oxidase/0.452
3cvkN34Genome polyprotein2.7.7.480.452
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3ekuCY9Actin-5C/0.452
3inwJZBHeat shock protein HSP 90-alpha/0.452
3ipuO40Oxysterols receptor LXR-alpha/0.452
3oq6PFBAlcohol dehydrogenase E chain1.1.1.10.452
3sfi3SFHTH-type transcriptional regulator EthR/0.452
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.452
4bfxZVXPantothenate kinase2.7.1.330.452
4ia1BIVVitamin D3 receptor A/0.452
4iah1DXAlr2278 protein/0.452
4ktkKTKCytochrome P450/0.452
4l98LRGPeroxisome proliferator-activated receptor gamma/0.452
4q0a4OAVitamin D3 receptor A/0.452
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.452
5cdgPFBAlcohol dehydrogenase E chain1.1.1.10.452
1byeATAGlutathione S-transferase 12.5.1.180.451
1ex75GPGuanylate kinase2.7.4.80.451
1ia4TQ6Dihydrofolate reductase1.5.1.30.451
1jqiCAAShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.451
1kzjCB3Thymidylate synthase/0.451
1s7lCOAAcetyl transferase/0.451
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.451
1t79DHTAndrogen receptor/0.451
1tilATPAnti-sigma F factor/0.451
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.451
2e8sSAHDiphthine synthase/0.451
2ejzSAHDiphthine synthase/0.451
2gvcFADThiol-specific monooxygenase1.14.130.451
2hk9NAPShikimate dehydrogenase (NADP(+))/0.451
2po7CHDFerrochelatase, mitochondrial4.99.1.10.451
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3nefPYVAbscisic acid receptor PYL1/0.451
3nxvD2FDihydrofolate reductase1.5.1.30.451
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.451
3u2lFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.451
3vspEK8Peroxisome proliferator-activated receptor gamma/0.451
4bb2STRCorticosteroid-binding globulin/0.451
4c6uTLG3-oxoacyl-ACP synthase/0.451
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.451
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.451
4klaCHDFerrochelatase, mitochondrial4.99.1.10.451
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.451
4m4922YL-lactate dehydrogenase A chain1.1.1.270.451
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.451
1gw2FERPeroxidase C1A1.11.1.70.450
1hndCOA3-oxoacyl-[acyl-carrier-protein] synthase 3/0.450
1rjkVDZVitamin D3 receptor/0.450
1s9dAFBCytohesin-2/0.450
1s9dAFBADP-ribosylation factor 1/0.450
1sqqOSTCytochrome b/0.450
1sqvUHDCytochrome b/0.450
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.450
1txiTX5Vitamin D3 receptor/0.450
1vbiNADMalate/L-lactate dehydrogenase family protein/0.450
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
1xuoLA1Integrin alpha-L/0.450
1yzqGNPRas-related protein Rab-6A/0.450
2bgsNDPAldose reductase1.1.1.210.450
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.450
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.450
2gzl2AA2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.450
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
2pg0FADAcyl-CoA dehydrogenase/0.450
3c3xNAPEugenol synthase 11.1.1.3180.450
3d75NBBPheromone-binding protein ASP1/0.450
3gu83GUDeath-associated protein kinase 12.7.11.10.450
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.450
3idsNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.450
3jw3TOPDihydrofolate reductase/0.450
3p9kCIYCaffeic acid O-methyltransferase/0.450
3w0aDS5Vitamin D3 receptor/0.450
3w0jT08Vitamin D3 receptor/0.450
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.450
3zkuHCVIsopenicillin N synthase1.21.3.10.450
4bkjSTIEpithelial discoidin domain-containing receptor 12.7.10.10.450
4ek1CAMCamphor 5-monooxygenase1.14.15.10.450
4epq0RRPoly(ADP-ribose) glycohydrolase/0.450
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.290.450
4iarERM5-hydroxytryptamine receptor 1B/0.450
4jq3NAPAldo-keto reductase family 1 member C2/0.450
5iua6DXAdenosine receptor A2a/0.450
1t65DHTAndrogen receptor/0.449
1tkaN3TTransketolase 12.2.1.10.449
2aa6STRMineralocorticoid receptor/0.449
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2bpoNAPNADPH--cytochrome P450 reductase/0.449
2c29NAPDihydroflavonol 4-reductase/0.449
2hc4VDXVitamin D3 receptor A/0.449
2iviACWIsopenicillin N synthase1.21.3.10.449
2ociTYCValacyclovir hydrolase3.10.449
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.449
2vczVC3Hematopoietic prostaglandin D synthase/0.449
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.449
2yg5FADPutrescine oxidase/0.449
3arvSAUChitinase A/0.449
3cgdCOACoenzyme A disulfide reductase/0.449
3dauMTXDihydrofolate reductase1.5.1.30.449
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3l0lHC3Nuclear receptor ROR-gamma/0.449
3v9v21LPeroxisome proliferator-activated receptor gamma/0.449
4hkkAGITankyrase-22.4.2.300.449
4jvr1MTE3 ubiquitin-protein ligase Mdm26.3.20.449
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
4ldkFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.449
4mleVO1Glucokinase2.7.1.20.449
4rtbSAMPutative thiazole biosynthesis protein ThiH/0.449
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.449
5kjePFBAlcohol dehydrogenase E chain1.1.1.10.449
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.448
1d6w00RProthrombin3.4.21.50.448
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.448
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.448
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.448
1qi1NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase1.2.1.90.448
1t4u81AProthrombin3.4.21.50.448
1uyhPU0Heat shock protein HSP 90-alpha/0.448
1vi0DCCFatty acid metabolism regulator protein/0.448
1z5cADPType 2 DNA topoisomerase 6 subunit B/0.448
2amaDHTAndrogen receptor/0.448
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.448
2c42TPPPyruvate synthase/0.448
2oadGTBGlutathione S-transferase P 12.5.1.180.448
2oaxSNLMineralocorticoid receptor/0.448
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
2ozrGG1Collagenase 33.4.240.448
2pixDHTAndrogen receptor/0.448
2w6pOA4Biotin carboxylase6.3.4.140.448
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.448
2xb8XNW3-dehydroquinate dehydratase4.2.1.100.448
2z1wBDIQueuine tRNA-ribosyltransferase2.4.2.290.448
2zb8IMNProstaglandin reductase 21.3.1.480.448
2zi53L1Deoxycytidine kinase2.7.1.740.448
3elm24FCollagenase 33.4.240.448
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.448
3k99PFTHeat shock protein HSP 90-alpha/0.448
3kpzZNEVitamin D3 receptor/0.448
3m13FADMonomeric sarcosine oxidase1.5.3.10.448
3qlxQLRUncharacterized protein/0.448
4bqwQNMEgl nine homolog 1/0.448
4c717RD3-oxoacyl-ACP synthase/0.448
4c72TLG3-oxoacyl-ACP synthase/0.448
4do30LAFatty-acid amide hydrolase 13.5.1.990.448
4g8cC6LAlpha/beta hydrolase fold protein/0.448
4h9506UDihydrofolate reductase1.5.1.30.448
4n3l2FNProthrombin3.4.21.50.448
4n3r2GUTankyrase-12.4.2.300.448
5cdsPFBAlcohol dehydrogenase E chain1.1.1.10.448
5fsxADPUncharacterized protein/0.448
1fm4DXCMajor pollen allergen Bet v 1-L/0.447
1vj3TABDihydrofolate reductase1.5.1.30.447
1yhnGTPRas-related protein Rab-7a/0.447
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.447
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.447
2eniSAHDiphthine synthase/0.447
2jlaTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.447
2pksG44Prothrombin3.4.21.50.447
2r2mI50Prothrombin3.4.21.50.447
2wzbADPPhosphoglycerate kinase 12.7.2.30.447
2xf3J01Uncharacterized protein/0.447
2xk730ESerine/threonine-protein kinase Nek22.7.11.10.447
2y05RALProstaglandin reductase 1/0.447
3bldPRFQueuine tRNA-ribosyltransferase2.4.2.290.447
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.447
3k7mFAD6-hydroxy-L-nicotine oxidase/0.447
3lfcZ86Mitogen-activated protein kinase 14/0.447
3nmhPYVAbscisic acid receptor PYL2/0.447
3phiNDPShikimate dehydrogenase (NADP(+))/0.447
3qh23NMThiazole tautomerase/0.447
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.447
3thrC2FGlycine N-methyltransferase2.1.1.200.447
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.447
3wrmCAMCamphor 5-monooxygenase1.14.15.10.447
4a81DXCMajor pollen allergen Bet v 1-A/0.447
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4dbc3QPAspartate aminotransferase2.6.1.10.447
4jhz1KVBeta-glucuronidase3.2.1.310.447
4pzdNAD3-Hydroxyacyl-CoA dehydrogenase/0.447
4z9rNADOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.447
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.447
1db1VDXVitamin D3 receptor/0.446
1dhiMTXDihydrofolate reductase1.5.1.30.446
1gt5BZQOdorant-binding protein/0.446
1hb3SCVIsopenicillin N synthase1.21.3.10.446
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.446
1kceCB3Thymidylate synthase/0.446
1kl2FONSerine hydroxymethyltransferase/0.446
1pr9NAPL-xylulose reductase1.1.1.100.446
1w78PD8Dihydrofolate synthase/folylpolyglutamate synthase6.3.2.120.446
1ygjRMCPyridoxal kinase2.7.1.350.446
1z7yAA5Cysteine synthase 12.5.1.470.446
1zprCB3Thymidylate synthase/0.446
2bu9HFVIsopenicillin N synthase1.21.3.10.446
2cy0NAPShikimate dehydrogenase (NADP(+))/0.446
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.446
2fszOHTEstrogen receptor beta/0.446
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.446
2hbhXE4Vitamin D3 receptor A/0.446
2j40NAD1-pyrroline-5-carboxylate dehydrogenase/0.446
2pk3GDDGDP-6-deoxy-D-mannose reductase/0.446
2wpxACOOrf14/0.446
2x1hX1HProstaglandin reductase 310.446
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.446
3cwkREACellular retinoic acid-binding protein 2/0.446
3d7zGK5Mitogen-activated protein kinase 14/0.446
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3e51N35Genome polyprotein2.7.7.480.446
3ha5SFGHydroxymycolate synthase MmaA42.1.10.446
3hucG97Mitogen-activated protein kinase 14/0.446
3id8MRKGlucokinase2.7.1.20.446
3lfeZ84Mitogen-activated protein kinase 14/0.446
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.446
3ndvAICBeta-peptidyl aminopeptidase BapA/0.446
3nj0PYVAbscisic acid receptor PYL2/0.446
3nmpPYVAbscisic acid receptor PYL2/0.446
3oadLPORenin3.4.23.150.446
3p2oNADBifunctional protein FolD/0.446
3qyw6PBMitogen-activated protein kinase 12.7.11.240.446
3t8xT8XT-cell surface glycoprotein CD1b/0.446
4az0S61Lysosomal protective protein3.4.16.50.446
4bb3KKAIsopenicillin N synthase1.21.3.10.446
4ehyADPTetraacyldisaccharide 4'-kinase/0.446
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4nbb9CATerminal oxygenase component of carbazole/0.446
4rquNADAlcohol dehydrogenase class-P/0.446
4twpAXITyrosine-protein kinase ABL12.7.10.20.446
4w6z8IDAlcohol dehydrogenase 11.1.1.10.446
4xyeNADFormate dehydrogenase/0.446
5it12OHPutative cytochrome P450/0.446
3uonQNBMuscarinic acetylcholine receptor M2/0.446
1blzACVIsopenicillin N synthase1.21.3.10.445
1dljUGAUDP-glucose 6-dehydrogenase/0.445
1jx0DFVChalcone--flavonone isomerase 15.5.1.60.445
1klkPMDDihydrofolate reductase1.5.1.30.445
1n77ATPGlutamate--tRNA ligase6.1.1.170.445
1r2jFADFkbI/0.445
1u65CP0Acetylcholinesterase3.1.1.70.445
1w06W05Isopenicillin N synthase1.21.3.10.445
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
2a9z26AAdenosine kinase2.7.1.200.445
2b8jADNClass B acid phosphatase3.1.3.20.445
2ffqGSPRas-related protein Rab-6B/0.445
2fs4PZ1Renin3.4.23.150.445
2h55DZ8Heat shock protein HSP 90-alpha/0.445
2ipjFFAAldo-keto reductase family 1 member C2/0.445
2qblCAMCamphor 5-monooxygenase1.14.15.10.445
2rabNADGlutathione amide reductase/0.445
2w9hTOPDihydrofolate reductase1.5.1.30.445
2x9vTMQPteridine reductase/0.445
2xk6EQHSerine/threonine-protein kinase Nek22.7.11.10.445
2xlsFADPutative flavin-containing monooxygenase/0.445
2yegXQGHeat shock protein HSP 90-alpha/0.445
2znoS44Peroxisome proliferator-activated receptor gamma/0.445
2zznSAMtRNA (guanine(37)-N1)-methyltransferase Trm5b2.1.1.2280.445
3anpDCCTranscriptional repressor, TetR family/0.445
3cgcCOACoenzyme A disulfide reductase/0.445
3f0aACOSpermidine N(1)-acetyltransferase/0.445
3gwfNAPCyclohexanone monooxygenase/0.445
3l034OHEstrogen receptor/0.445
3qykIE2Carbonic anhydrase 24.2.1.10.445
3ujlA8SAbscisic acid receptor PYL2/0.445
4buxF35Tankyrase-22.4.2.300.445
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.445
4egnTWOCytochrome P450/0.445
4fqsLYAThymidylate synthase ThyA/0.445
4g1y0VOVitamin D3 receptor A/0.445
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.445
4hw219HInduced myeloid leukemia cell differentiation protein Mcl-1/0.445
4m6l21VDihydrofolate reductase1.5.1.30.445
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4n4v2GYTankyrase-12.4.2.300.445
4o71CPBBromodomain-containing protein 4/0.445
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.445
4ofuDHTAndrogen receptor/0.445
4u95MIYMultidrug efflux pump subunit AcrB/0.445
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.445
4xd2NAIAlcohol dehydrogenase E chain1.1.1.10.445
5ej7TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.445
1ad3NADAldehyde dehydrogenase, dimeric NADP-preferring/0.444
1c7oPPGHemolysin/0.444
1gj5130Prothrombin3.4.21.50.444
1n2vBDIQueuine tRNA-ribosyltransferase2.4.2.290.444
1qy5NECEndoplasmin/0.444
1s0zEB1Vitamin D3 receptor/0.444
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2e16SAHDiphthine synthase/0.444
2ftoTMPThymidylate synthase/0.444
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
2v95HCYCorticosteroid-binding globulin/0.444
2vdvSAMtRNA (guanine-N(7)-)-methyltransferase/0.444
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.444
3eon341Glutaryl-CoA dehydrogenase/0.444
3grySAMProbable ribosomal RNA small subunit methyltransferase A/0.444
3gusN11Glutathione S-transferase P2.5.1.180.444
3gy0NAPNAD(P)-dependent oxidoreductase/0.444
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.444
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
3iwkNADAminoaldehyde dehydrogenase/0.444
3kxoKXOHematopoietic prostaglandin D synthase/0.444
3ldfSAHUncharacterized protein/0.444
3orfNADDihydropteridine reductase1.5.1.340.444
3q5kD1UHeat shock protein 83-1/0.444
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
3t88S0N1,4-dihydroxy-2-naphthoyl-CoA synthase/0.444
4a87NARMajor pollen allergen Bet v 1-A/0.444
4bgiNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4c1fX8ZMetallo-beta-lactamase type 2/0.444
4c8b0LIReceptor-interacting serine/threonine-protein kinase 22.7.11.10.444
4dhyS41Glucokinase2.7.1.20.444
4fxy0W2Neurolysin, mitochondrial3.4.24.160.444
4fyhTR52'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.444
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4hyf1AKTankyrase-22.4.2.300.444
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
5cshATPCasein kinase II subunit alpha2.7.11.10.444
5il2SAHN6-adenosine-methyltransferase 70 kDa subunit/0.444
1af00Z9Serralysin3.4.24.400.443
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.443
1efzPRFQueuine tRNA-ribosyltransferase2.4.2.290.443
1kkq471Peroxisome proliferator-activated receptor alpha/0.443
1kqwRTLCellular retinol-binding protein type II/0.443
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.443
1pt8ACOFormyl-CoA:oxalate CoA-transferase/0.443
1rd4L08Integrin alpha-L/0.443
1rq1FADEndoplasmic oxidoreductin-11.8.40.443
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.443
1ur5NADMalate dehydrogenase/0.443
1zbdGTPRas-related protein Rab-3A/0.443
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.443
2cy2ACOProbable acetyltransferase/0.443
2e8qSAHDiphthine synthase/0.443
2gblATPCircadian clock protein kinase KaiC2.7.11.10.443
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.443
2hcdBIVVitamin D3 receptor A/0.443
2huxSAHDiphthine synthase/0.443
2q4bNAPUncharacterized protein At5g02240/0.443
2rr1W8RGenome polyprotein/0.443
2vz0D64Pteridine reductase/0.443
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.443
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.443
3cgeNDPCoenzyme A disulfide reductase/0.443
3csjCBLGlutathione S-transferase P2.5.1.180.443
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3dvlATPCircadian clock protein kinase KaiC2.7.11.10.443
3eksCY9Actin-5C/0.443
3frdDHFDihydrofolate reductase1.5.1.30.443
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.443
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.443
3i0pNADMalate dehydrogenase, putative/0.443
3mgdACOPredicted acetyltransferase/0.443
3nxyD2HDihydrofolate reductase1.5.1.30.443
3siiA1RUncharacterized protein/0.443
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.443
4bfzZVZPantothenate kinase2.7.1.330.443
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4c3yFAD3-ketosteroid dehydrogenase/0.443
4cdmFO1Deoxyribodipyrimidine photolyase/0.443
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.443
4d04NAPPhenylacetone monooxygenase1.14.13.920.443
4dwvNAJAlcohol dehydrogenase E chain1.1.1.10.443
4eiyZMAAdenosine receptor A2a/0.443
4eqgA5AHistidine triad nucleotide-binding protein 130.443
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.443
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.443
4hdrDMDNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase/0.443
4hdrDMDArsB/0.443
4ise1FWGlucokinase2.7.1.20.443
4mwzSAMPhosphoethanolamine N-methyltransferase, putative/0.443
4v26TF3[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.443
4xbfFADLysine-specific histone demethylase 1A10.443
5bp9SAHPutative methyltransferase protein/0.443
5g53NECAdenosine receptor A2a/0.443
1aiqCB3Thymidylate synthase/0.442
1c1dNAIPhenylalanine dehydrogenase/0.442
1cqp803Integrin alpha-L/0.442
1n9mBTNStreptavidin/0.442
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1trkTPPTransketolase 12.2.1.10.442
1umaIN2Prothrombin3.4.21.50.442
1x7hNDPPutative ketoacyl reductase1.3.10.442
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.442
2a4nCOAAac(6')-Ii protein/0.442
2aclREARetinoic acid receptor RXR-alpha/0.442
2ahrNAPPyrroline-5-carboxylate reductase/0.442
2az3CDPNucleoside diphosphate kinase/0.442
2dw4FADLysine-specific histone demethylase 1A10.442
2e7rSAHDiphthine synthase/0.442
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
2p1v5TNRetinoic acid receptor RXR-alpha/0.442
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.442
2rehFADNitroalkane oxidase1.7.3.10.442
2xw19NVSerum albumin/0.442
2zhf49UProthrombin3.4.21.50.442
3bbpGTPRas-related protein Rab-6A/0.442
3dd125DGlycogen phosphorylase, liver form2.4.1.10.442
3fr5I4AFatty acid-binding protein, adipocyte/0.442
3gtsD3MDdmC/0.442
3negPYVAbscisic acid receptor PYL1/0.442
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.442
3ou2SAHSAM-dependent methyltransferase/0.442
3qizQI2Botulinum neurotoxin type A3.4.24.690.442
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.442
4bftZVTPantothenate kinase2.7.1.330.442
4e2bFMNDehydrogenase/0.442
4eh8IRGMitogen-activated protein kinase 14/0.442
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.442
4g1d0VKVitamin D3 receptor A/0.442
4ia3BIVVitamin D3 receptor A/0.442
4iyg1HUStrictosidine synthase4.3.3.20.442
4jtrIZPAldo-keto reductase family 1 member C2/0.442
4l33F70Tankyrase-22.4.2.300.442
4o7uTHFThymidylate synthase/0.442
4o8fBRLPeroxisome proliferator-activated receptor gamma/0.442
4rujVDXVitamin D3 receptor A/0.442
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.442
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.442
5fm6ADPRuvB-like helicase/0.442
5iu4ZMAAdenosine receptor A2a/0.442
5k2dZMAAdenosine receptor A2a/0.442
1aqxGTDGlutathione S-transferase P2.5.1.180.441
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.441
1cjvDADAdenylate cyclase type 2/0.441
1cjvDADAdenylate cyclase type 5/0.441
1d7yFADFerredoxin reductase/0.441
1dhfFOLDihydrofolate reductase1.5.1.30.441
1e2kTMCThymidine kinase/0.441
1gs3EQUSteroid Delta-isomerase5.3.3.10.441
1gs4ZK5Androgen receptor/0.441
1hy3PPSEstrogen sulfotransferase2.8.2.40.441
1p5rCOAFormyl-CoA:oxalate CoA-transferase/0.441
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.441
1t5zDHTAndrogen receptor/0.441
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
1yc2NADNAD-dependent protein deacylase 2/0.441
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.441
2ci01CMLanosterol 14-alpha demethylase1.14.13.700.441
2dhfDZFDihydrofolate reductase1.5.1.30.441
2ek3SAHDiphthine synthase/0.441
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2ghlLIBMitogen-activated protein kinase 14/0.441
2ih5NEAModification methylase TaqI2.1.1.720.441
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.441
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.441
2jkkBI9Focal adhesion kinase 12.7.10.20.441
2othNIMBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.441
2owvSAHDiphthine synthase/0.441
2rm2W43Genome polyprotein/0.441
2wpwACOOrf14/0.441
2y4gTIRTamL/0.441
2ylpTESAndrogen receptor/0.441
2zc922UProthrombin3.4.21.50.441
2zf051UProthrombin3.4.21.50.441
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.441
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.441
3bloQEIQueuine tRNA-ribosyltransferase2.4.2.290.441
3c1kT15Prothrombin3.4.21.50.441
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.441
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.441
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.441
3occDIHPurine nucleoside phosphorylase DeoD-type/0.441
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
3pgtGBXGlutathione S-transferase P2.5.1.180.441
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.441
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
3rthRTHBeta-secretase 13.4.23.460.441
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4avwG18Tankyrase-22.4.2.300.441
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.441
4e0u0MVCyclic dipeptide N-prenyltransferase/0.441
4h9753SDihydrofolate reductase1.5.1.30.441
4iilRBFMembrane lipoprotein TpN38(b)/0.441
4j6dTESCytochrome P450 monooxygenase/0.441
4jq4IMNAldo-keto reductase family 1 member C2/0.441
4l9q9TPSerum albumin/0.441
4nfhPFBAlcohol dehydrogenase E chain1.1.1.10.441
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4qzuRTLRetinol-binding protein 2/0.441
4rrcA3TProbable threonine--tRNA ligase 26.1.1.30.441
4tjy3GNTankyrase-22.4.2.300.441
4ykgNADAlkyl hydroperoxide reductase subunit F1.8.10.441
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.441
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.441
6gsuGPSGlutathione S-transferase Mu 12.5.1.180.441
5jqhCAUBeta-2 adrenergic receptor/0.441
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.440
1dg5TOPDihydrofolate reductase1.5.1.30.440
1dgfNDPCatalase1.11.1.60.440
1gqyACPUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.440
1i2lDCSAminodeoxychorismate lyase4.1.3.380.440
1m8kNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.440
1n5vNOMActVA 6 protein/0.440
1o2g696Prothrombin3.4.21.50.440
1t4v14AProthrombin3.4.21.50.440
1t7rDHTAndrogen receptor/0.440
1w29TS06,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
2ab8MTPAdenosine kinase2.7.1.200.440
2b36NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2bjsACVIsopenicillin N synthase1.21.3.10.440
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.440
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.440
2e20B4PPropionate kinase/0.440
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2p6kSAHDiphthine synthase/0.440
2pgtGPRGlutathione S-transferase P2.5.1.180.440
2pitDHTAndrogen receptor/0.440
2pnuENMAndrogen receptor/0.440
2uxwTH3Very long-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.90.440
2wo7ASVIsopenicillin N synthase1.21.3.10.440
2xi4AFTAcetylcholinesterase3.1.1.70.440
2ydoADNAdenosine receptor A2a/0.440
2yj4ATPCopper-transporting ATPase/0.440
2ykcYKCHeat shock protein HSP 90-alpha/0.440
2zb1GK4Mitogen-activated protein kinase 14/0.440
2zifSAMMethyltransferase/0.440
2zl9VDAVitamin D3 receptor/0.440
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.440
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.440
3eem53VUncharacterized protein/0.440
3friSAH16S rRNA methylase/0.440
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3hl7I46Mitogen-activated protein kinase 14/0.440
3l71AZOCytochrome b/0.440
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3nglNAPBifunctional protein FolD/0.440
3nhkVAPRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
3qiyQI1Botulinum neurotoxin type A3.4.24.690.440
3s6aANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.440
3sjuNDPKeto reductase/0.440
3sm8FNKFAD-dependent catabolic D-arginine dehydrogenase DauA/0.440
3ssmSAHMycinamicin VI 2''-O-methyltransferase/0.440
3t4lZEAHistidine kinase 42.7.13.30.440
3v1uHXC3-oxoacyl-(Acyl-carrier-protein) reductase/0.440
3vi5M4MHematopoietic prostaglandin D synthase/0.440
3wv7ADPHmd co-occurring protein HcgE/0.440
4g2gTDHMycocyclosin synthase1.14.21.90.440
4g2wNI0cGMP-specific 3',5'-cyclic phosphodiesterase/0.440
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.440
4iwv1J9Glucokinase2.7.1.20.440
4k7aDHTAndrogen receptor/0.440
4l0i1UWTankyrase-22.4.2.300.440
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4oznATPAmmonium transporter/0.440
4p5fAR6Inosine-uridine nucleoside N-ribohydrolase/0.440
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.440
4yntFDAGlucose oxidase, putative/0.440
5iubCLRAdenosine receptor A2a/0.440
5iu86DZAdenosine receptor A2a/0.440