Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
4xbf | FAD | Lysine-specific histone demethylase 1A | 1 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 1.000 | |
2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.602 | |
2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.573 | |
2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.490 | |
3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.454 | |
4gdp | FAD | Polyamine oxidase FMS1 | / | 0.444 | |
3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.440 |