sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4x28	FDA	Acyl-CoA dehydrogenase FadE26

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4x28	FDA	Acyl-CoA dehydrogenase FadE26	/	1.000
4x28	FDA	Acyl-CoA dehydrogenase FadE27	/	1.000
2z1q	FAD	Acyl-CoA dehydrogenase	/	0.498
3owa	FAD	Acyl-CoA dehydrogenase	/	0.496
5jsc	FAD	Putative acyl-CoA dehydrogenase	/	0.470
3nf4	FAD	Acyl-CoA dehydrogenase domain-containing protein	/	0.468
3r7k	FDA	Probable acyl CoA dehydrogenase	/	0.467
3u33	FAD	Putative acyl-CoA dehydrogenase AidB	1.3.99	0.462
3pfd	FDA	Acyl-CoA dehydrogenase FadE25	/	0.457
1rx0	FAD	Isobutyryl-CoA dehydrogenase, mitochondrial	1.3.99	0.447