sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4wrk | DUP | DUTPase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4wrk | DUP | DUTPase | / | 1.000 | |
| 3t70 | DU4 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.493 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.484 | |
| 2xy3 | DUP | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.478 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.474 | |
| 2oke | DUP | DUTP pyrophosphatase | / | 0.473 | |
| 2we3 | DUT | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.462 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.462 | |
| 2ol0 | DUD | DUTP pyrophosphatase | / | 0.458 | |
| 1snf | UMP | Deoxyuridine 5'-triphosphate nucleotidohydrolase | 3.6.1.23 | 0.450 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.450 | |
| 1ja0 | NAP | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.444 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.444 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.443 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.442 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.440 |