Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4wevSUZAldo-keto reductase family 1 member B101.1.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4wevSUZAldo-keto reductase family 1 member B101.1.11.000
5liu388Aldo-keto reductase family 1 member B101.1.10.569
1zuaTOLAldo-keto reductase family 1 member B101.1.10.538
2pdlTOLAldose reductase1.1.1.210.500
2fzdTOLAldose reductase1.1.1.210.486
2pdh47DAldose reductase1.1.1.210.482
1ah3TOLAldose reductase1.1.1.210.479
2fzbTOLAldose reductase1.1.1.210.462
4fam0SZAldo-keto reductase family 1 member C3/0.452