sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4u2s	FDA	Cholesterol oxidase	1.1.3.6

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4u2s	FDA	Cholesterol oxidase	1.1.3.6	1.000
1cc2	FAD	Cholesterol oxidase	1.1.3.6	0.744
1mxt	FAE	Cholesterol oxidase	1.1.3.6	0.742
1n4u	FAE	Cholesterol oxidase	1.1.3.6	0.703
4u2l	SFD	Cholesterol oxidase	1.1.3.6	0.695
1b4v	FAD	Cholesterol oxidase	1.1.3.6	0.600
1n4v	FAD	Cholesterol oxidase	1.1.3.6	0.569
4xwr	FAD	Cholesterol oxidase	1.1.3.6	0.567
4xxg	FAD	Cholesterol oxidase	1.1.3.6	0.542
1cbo	FAD	Cholesterol oxidase	1.1.3.6	0.521
3cnj	FAD	Cholesterol oxidase	1.1.3.6	0.520
4rek	FAD	Cholesterol oxidase	1.1.3.6	0.507
3gyj	FAD	Cholesterol oxidase	1.1.3.6	0.505
3cox	FAD	Cholesterol oxidase	1.1.3.6	0.494
1b8s	FAD	Cholesterol oxidase	1.1.3.6	0.466
3gyi	FAD	Cholesterol oxidase	1.1.3.6	0.465