sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4txz | G2P | Cyclic GMP-AMP synthase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4txz | G2P | Cyclic GMP-AMP synthase | / | 1.000 | |
| 4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.607 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.471 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.458 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.455 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.454 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.450 | |
| 4hms | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.450 | |
| 2vtb | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.449 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.449 | |
| 2y4g | TIR | TamL | / | 0.446 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.446 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.446 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.444 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.444 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.444 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.443 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.443 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 3w8r | ACP | Uridine kinase | / | 0.443 | |
| 1vso | AT1 | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.440 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.440 |