sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4twl | ASC | Dioscorin 5 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4twl | ASC | Dioscorin 5 | / | 1.000 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.472 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.469 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.464 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.453 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 3u8f | FGM | Ribosome inactivating protein | / | 0.445 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.444 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.444 | |
| 1woo | THG | Aminomethyltransferase | / | 0.442 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 4jtp | ASC | Ribosome inactivating protein | / | 0.440 |