sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4tnr	DTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4tnr	DTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	1.000
4tnp	DCP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.595
4tnz	DTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.558
4tnq	TTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.517
4qfy	DGT	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.507
4to5	TTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.500
4to6	DGT	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.452
4tnx	DGT	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.441