sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4tmn	0PK	Thermolysin	3.4.24.27

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4tmn	0PK	Thermolysin	3.4.24.27	1.000
2tmn	0FA	Thermolysin	3.4.24.27	0.794
6tmn	0PI	Thermolysin	3.4.24.27	0.752
4tln	LNO	Thermolysin	3.4.24.27	0.678
3t74	UBY	Thermolysin	3.4.24.27	0.587
4h57	0PJ	Thermolysin	3.4.24.27	0.583
1qf2	TI3	Thermolysin	3.4.24.27	0.578
3t8d	UBV	Thermolysin	3.4.24.27	0.578
4d9w	X32	Thermolysin	3.4.24.27	0.573
3t8h	UBS	Thermolysin	3.4.24.27	0.564
3t87	UBZ	Thermolysin	3.4.24.27	0.560
3t8c	UBW	Thermolysin	3.4.24.27	0.559
3for	ZNP	Thermolysin	3.4.24.27	0.554
3fgd	BYA	Thermolysin	3.4.24.27	0.530
1n2j	PAF	Pantothenate synthetase	6.3.2.1	0.440