sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4tmb	FMN	Old yellow enzyme

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4tmb	FMN	Old yellow enzyme	/	1.000
4rnv	FMN	NADPH dehydrogenase 1	1.6.99.1	0.555
1icp	FMN	12-oxophytodienoate reductase 1	1.3.1.42	0.492
4rnu	FMN	NADPH dehydrogenase 1	1.6.99.1	0.476
3hgs	FMN	12-oxophytodienoate reductase 3	1.3.1.42	0.475
4rnw	FMN	NADPH dehydrogenase 1	1.6.99.1	0.470
3hgo	FMN	12-oxophytodienoate reductase 3	1.3.1.42	0.461
2hs8	FMN	12-oxophytodienoate reductase 3	1.3.1.42	0.459
1vji	FMN	12-oxophytodienoate reductase 1	1.3.1.42	0.454
1bwk	FMN	NADPH dehydrogenase 1	1.6.99.1	0.451
1q45	FMN	12-oxophytodienoate reductase 3	1.3.1.42	0.444
1ics	FMN	12-oxophytodienoate reductase 1	1.3.1.42	0.440