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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4stdBFSScytalone dehydratase4.2.1.94

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4stdBFSScytalone dehydratase4.2.1.941.000
5stdUNNScytalone dehydratase4.2.1.940.622
6stdMS2Scytalone dehydratase4.2.1.940.617
3stdMQ0Scytalone dehydratase4.2.1.940.594
2stdCRPScytalone dehydratase4.2.1.940.579
1stdBFSScytalone dehydratase4.2.1.940.563
7stdCRPScytalone dehydratase4.2.1.940.545
3zkyWT4Isopenicillin N synthase1.21.3.10.537
2vbpVB1Isopenicillin N synthase1.21.3.10.524
1oc1ASVIsopenicillin N synthase1.21.3.10.515
3nmpPYVAbscisic acid receptor PYL2/0.511
2wo7ASVIsopenicillin N synthase1.21.3.10.510
1qjfACSIsopenicillin N synthase1.21.3.10.508
4pnmNU1Tankyrase-22.4.2.300.508
2vcmM11Isopenicillin N synthase1.21.3.10.507
2y60M8FIsopenicillin N synthase1.21.3.10.507
3t37FADPyridoxine 4-oxidase/0.507
4iae1DXAlr2278 protein/0.507
2bu9HFVIsopenicillin N synthase1.21.3.10.505
1el4CTZObelin/0.504
2mm3CHOGastrotropin/0.504
3h3qH13Collagen type IV alpha-3-binding protein/0.504
1ygjRMCPyridoxal kinase2.7.1.350.501
1obnASVIsopenicillin N synthase1.21.3.10.499
1fmlRTLRetinol dehydratase/0.497
1blzACVIsopenicillin N synthase1.21.3.10.495
2vbdV10Isopenicillin N synthase1.21.3.10.495
1s7gNADNAD-dependent protein deacylase 2/0.494
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.494
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.493
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.493
3h3t16HCollagen type IV alpha-3-binding protein/0.493
3iktNADRedox-sensing transcriptional repressor Rex/0.492
3njoPYVAbscisic acid receptor PYR1/0.492
1qiqACCIsopenicillin N synthase1.21.3.10.490
1qv1CZHObelin/0.489
4fam0SZAldo-keto reductase family 1 member C3/0.489
1b2lNDCAlcohol dehydrogenase1.1.1.10.488
1uhhCZPAequorin-2/0.488
3zoiM2WIsopenicillin N synthase1.21.3.10.488
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.487
4bfxZVXPantothenate kinase2.7.1.330.486
4jqh1MFAlr2278 protein/0.486
4h380YXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.485
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.483
4iah1DXAlr2278 protein/0.483
4psbGA3Cytokinin-specific binding protein/0.483
1dghNDPCatalase1.11.1.60.482
1jf0CZHObelin/0.482
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.481
1toiHCIAspartate aminotransferase2.6.1.10.481
3c3xNAPEugenol synthase 11.1.1.3180.481
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.481
4ggzBTNBll1558 protein/0.481
1hfqMOTDihydrofolate reductase1.5.1.30.480
1u1f183Uridine phosphorylase2.4.2.30.480
1yc2NADNAD-dependent protein deacylase 2/0.480
1hb1OCVIsopenicillin N synthase1.21.3.10.479
1yw8A75Methionine aminopeptidase 2/0.479
4l5b1UXDeoxycytidine kinase2.7.1.740.479
1xddAAYIntegrin alpha-L/0.478
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.478
2yatEEUEstrogen receptor/0.478
4aoaIK2Beta-phenylalanine transaminase2.6.10.478
4dvi2IWTankyrase-12.4.2.300.478
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.477
3mjrAC2Deoxycytidine kinase2.7.1.740.477
4bfvZVVPantothenate kinase2.7.1.330.477
1qv0CZHObelin/0.476
4jtqNAPAldo-keto reductase family 1 member C2/0.476
1jf2CZHObelin/0.475
4k4eK4ETankyrase-12.4.2.300.475
2bn4FADNADPH--cytochrome P450 reductase/0.474
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.474
3l6jZ90Alr2278 protein/0.474
3otwCOAPhosphopantetheine adenylyltransferase/0.474
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.473
1mtcGPRGlutathione S-transferase Mu 12.5.1.180.473
3pqbVGPPutative oxidoreductase/0.473
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.473
4kdrSAHUbiquinone biosynthesis O-methyltransferase/0.473
4n4v2GYTankyrase-12.4.2.300.473
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.473
7catNDPCatalase1.11.1.60.473
1uzwCDHIsopenicillin N synthase1.21.3.10.472
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.472
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.472
4boeCLRJapanin/0.472
4fhd0TTSpore photoproduct lyase/0.472
1tojHCIAspartate aminotransferase2.6.1.10.471
1w6jR71Lanosterol synthase5.4.99.70.471
2bjsACVIsopenicillin N synthase1.21.3.10.471
3q9bB3NAcetylpolyamine amidohydrolase/0.471
1dr5NAPDihydrofolate reductase1.5.1.30.470
1klkPMDDihydrofolate reductase1.5.1.30.470
2xviFADPutative flavin-containing monooxygenase/0.470
3nwlNDPCatalase1.11.1.60.470
4e37NDPCatalase1.11.1.60.470
4j6dTESCytochrome P450 monooxygenase/0.470
4kbn25UDihydrofolate reductase1.5.1.30.470
2zevIPEGeranylgeranyl pyrophosphate synthase/0.469
3nxtD2EDihydrofolate reductase1.5.1.30.469
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
4bb3KKAIsopenicillin N synthase1.21.3.10.469
4jlm1NNDeoxycytidine kinase2.7.1.740.469
4n4t2GVTankyrase-12.4.2.300.469
1fmjRTLRetinol dehydratase/0.468
1txtCAAHMG-CoA synthase/0.468
1vgrCOAFormyl-CoA:oxalate CoA-transferase/0.468
2ejzSAHDiphthine synthase/0.468
2uxoTACHTH-type transcriptional regulator TtgR/0.468
2yj4ATPCopper-transporting ATPase/0.468
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.468
3s3vTOPDihydrofolate reductase1.5.1.30.468
4twnB96Ephrin type-A receptor 32.7.10.10.468
1icqOPD12-oxophytodienoate reductase 11.3.1.420.467
1t91GTPRas-related protein Rab-7a/0.467
1upw444Oxysterols receptor LXR-beta/0.467
1yw7A41Methionine aminopeptidase 2/0.467
3c1oNAPEugenol synthase/0.467
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.467
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.467
3nu03TUDihydrofolate reductase1.5.1.30.467
4jyzATPGlutamine--tRNA ligase6.1.1.180.467
4l1xNAPAldo-keto reductase family 1 member C2/0.467
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.466
2cekN8TAcetylcholinesterase3.1.1.70.466
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.466
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.466
2vqqTFGHistone deacetylase 43.5.1.980.466
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.466
3elePLPAminotransferase/0.466
4jlj1NMDeoxycytidine kinase2.7.1.740.466
4k4fK4FTankyrase-12.4.2.300.466
4tjy3GNTankyrase-22.4.2.300.466
4u163C0Muscarinic acetylcholine receptor M3/0.466
1x8lOXRRetinol dehydratase/0.465
2nm2NEUDihydroneopterin aldolase/0.465
2y6fM9FIsopenicillin N synthase1.21.3.10.465
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.465
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.465
4kebFOLDihydrofolate reductase1.5.1.30.465
4pnrG18Tankyrase-22.4.2.300.465
1i05LTLMajor urinary protein 6/0.464
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.464
2gdzNAD15-hydroxyprostaglandin dehydrogenase [NAD(+)]1.1.1.1410.464
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.464
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
3h3r14HCollagen type IV alpha-3-binding protein/0.464
3p0fBAUUridine phosphorylase 22.4.2.30.464
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.464
4kbyC2EStimulator of interferon genes protein/0.464
4mt92D6Tankyrase-12.4.2.300.464
5cc9DDFDihydrofolate reductase1.5.1.30.464
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.463
1rftPXMPyridoxal kinase2.7.1.350.463
2bxqIMNSerum albumin/0.463
2h7jH7JCathepsin S3.4.22.270.463
2jb4A14Isopenicillin N synthase1.21.3.10.463
2ociTYCValacyclovir hydrolase3.10.463
2pdlTOLAldose reductase1.1.1.210.463
2z4y252Geranylgeranyl pyrophosphate synthase/0.463
3fhxPLPPyridoxal kinase2.7.1.350.463
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.463
3rsv3RSBeta-secretase 13.4.23.460.463
8catNDPCatalase1.11.1.60.463
1hfrMOTDihydrofolate reductase1.5.1.30.462
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.462
1ohkCOPDihydrofolate reductase1.5.1.30.462
2zsbADPPantothenate kinase2.7.1.330.462
3ekuCY9Actin-5C/0.462
3nxyD2HDihydrofolate reductase1.5.1.30.462
3r43ID8Aldo-keto reductase family 1 member C3/0.462
4jxxATPGlutamine--tRNA ligase6.1.1.180.462
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.462
2b36NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
2dhfDZFDihydrofolate reductase1.5.1.30.461
2e0nSAHPrecorrin-2 C20-methyltransferase/0.461
2pnuENMAndrogen receptor/0.461
2zevB71Geranylgeranyl pyrophosphate synthase/0.461
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
3dcsMZMCarbonic anhydrase 24.2.1.10.461
3dlaNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.461
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.461
4bj9UHBTankyrase-22.4.2.300.461
4ddrMMVDihydrofolate reductase1.5.1.30.461
4kfjFOLDihydrofolate reductase1.5.1.30.461
5dp2NAPCurF/0.461
1hb3SCVIsopenicillin N synthase1.21.3.10.460
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.460
3aosJH2Hemolymph juvenile hormone binding protein/0.460
3k4551PDihydrofolate reductase1.5.1.30.460
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.460
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.460
3zkuHCVIsopenicillin N synthase1.21.3.10.460
4bmpFMNProtein NrdI/0.460
5agyGTBTau class glutathione S-transferase/0.460
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.459
1s36CEIObelin/0.459
1s3uTQDDihydrofolate reductase1.5.1.30.459
2whqHI6Acetylcholinesterase3.1.1.70.459
3vf60H6Glucokinase2.7.1.20.459
4p9dTMPDeoxycytidylate deaminase/0.459
1dggNDPCatalase1.11.1.60.458
2rds1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.458
3f0aACOSpermidine N(1)-acetyltransferase/0.458
3hwxTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.458
4dch4DCGlucokinase2.7.1.20.458
4zqcF6FTryptophan synthase alpha chain/0.458
1bwlFMNNADPH dehydrogenase 11.6.99.10.457
1dliUDXUDP-glucose 6-dehydrogenase/0.457
1rpwDIDHTH-type transcriptional regulator QacR/0.457
1thnADPAnti-sigma F factor/0.457
2gv8NDPThiol-specific monooxygenase1.14.130.457
3egvSAHRibosomal protein L11 methyltransferase2.1.10.457
4dbc3QPAspartate aminotransferase2.6.1.10.457
4n1fCZHObelin/0.457
3emlZMAAdenosine receptor A2a/0.457
1dgbNDPCatalase1.11.1.60.456
1dr4HBIDihydrofolate reductase1.5.1.30.456
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
1nm6L86Prothrombin3.4.21.50.456
1xzqFONtRNA modification GTPase MnmE3.6.50.456
1ygkRRCPyridoxal kinase2.7.1.350.456
2iqdLPAAldose reductase1.1.1.210.456
3c3dFO12-phospho-L-lactate transferase/0.456
3djfBC3Purine nucleoside phosphorylase/0.456
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.456
3p2oNADBifunctional protein FolD/0.456
3zv7NHGAcetylcholinesterase3.1.1.70.456
4bfwZVWPantothenate kinase2.7.1.330.456
4esoNAPPutative oxidoreductase/0.456
4h7zGUNQueuine tRNA-ribosyltransferase2.4.2.290.456
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.456
1dgfNDPCatalase1.11.1.60.455
1drfFOLDihydrofolate reductase1.5.1.30.455
1pd9CO4Dihydrofolate reductase1.5.1.30.455
1zdwFLVPrenyltransferase/0.455
2on6IMHPurine nucleoside phosphorylase2.4.2.10.455
2xujTZ5Acetylcholinesterase3.1.1.70.455
3af0GDPPantothenate kinase2.7.1.330.455
3bloQEIQueuine tRNA-ribosyltransferase2.4.2.290.455
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.455
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3s41S41Glucokinase2.7.1.20.455
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
4e0u0MVCyclic dipeptide N-prenyltransferase/0.455
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.455
4jln18VDeoxycytidine kinase2.7.1.740.455
4lzwTHMUridine phosphorylase/0.455
1d3pBT3Prothrombin3.4.21.50.454
1muuGDXGDP-mannose 6-dehydrogenase1.1.1.1320.454
1odcA8BAcetylcholinesterase3.1.1.70.454
1ohjCOPDihydrofolate reductase1.5.1.30.454
1qrsATPGlutamine--tRNA ligase6.1.1.180.454
1w87FADFerredoxin--NADP reductase1.18.1.20.454
2po7CHDFerrochelatase, mitochondrial4.99.1.10.454
3hk1B64Fatty acid-binding protein, adipocyte/0.454
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.454
4fhf0TTSpore photoproduct lyase/0.454
4rgsV55Repressor protein/0.454
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.454
4rtbSAMPutative thiazole biosynthesis protein ThiH/0.454
1mvtDTMDihydrofolate reductase1.5.1.30.453
1touB1VFatty acid-binding protein, adipocyte/0.453
2ed3SAHDiphthine synthase/0.453
2iviACWIsopenicillin N synthase1.21.3.10.453
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
2vi5Y196,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
2z4sADPChromosomal replication initiator protein DnaA/0.453
3eksCY9Actin-5C/0.453
3h3sH15Collagen type IV alpha-3-binding protein/0.453
3ipq965Oxysterols receptor LXR-alpha/0.453
3ixp834Ecdysone receptor/0.453
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.453
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4cdmFO1Deoxyribodipyrimidine photolyase/0.453
4i5xFLFAldo-keto reductase family 1 member B101.1.10.453
4j3mAJ8Tankyrase-22.4.2.300.453
5liu388Aldo-keto reductase family 1 member B101.1.10.453
4daj0HKMuscarinic acetylcholine receptor M3/0.453
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.452
1swtBTNStreptavidin/0.452
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.452
1x1dSAHC-20 methyltransferase/0.452
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
2p15EZTEstrogen receptor/0.452
2pgtGPRGlutathione S-transferase P2.5.1.180.452
2vezACOGlucosamine 6-phosphate acetyltransferase, putative/0.452
3cukFADD-amino-acid oxidase1.4.3.30.452
4bftZVTPantothenate kinase2.7.1.330.452
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
4dbuBT9Aldo-keto reductase family 1 member C3/0.452
4fa30SLAldo-keto reductase family 1 member C3/0.452
1d3dBZTProthrombin3.4.21.50.451
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.451
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
2fl2ADPKinesin-like protein KIF11/0.451
2hxzH7JCathepsin S3.4.22.270.451
2qc8ADPGlutamine synthetase6.3.1.20.451
2rd2QSIGlutamine--tRNA ligase6.1.1.180.451
2rlcCHDCholoylglycine hydrolase3.5.1.240.451
3fhxPXLPyridoxal kinase2.7.1.350.451
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.451
3gncQQQGlutaryl-CoA dehydrogenase/0.451
3s55NADPutative short-chain dehydrogenase/reductase/0.451
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.451
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.451
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.451
5erm210Fusicoccadiene synthase4.2.3.430.451
1a26CNAPoly [ADP-ribose] polymerase 12.4.2.300.450
1eiiRTLRetinol-binding protein 2/0.450
1kmyBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.450
1lnmDTXBilin-binding protein/0.450
1u65CP0Acetylcholinesterase3.1.1.70.450
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
1xs7MMIBeta-secretase 13.4.23.460.450
2ga2A19Methionine aminopeptidase 2/0.450
2zs8ADPPantothenate kinase2.7.1.330.450
3fr5I4AFatty acid-binding protein, adipocyte/0.450
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4g8cC6LAlpha/beta hydrolase fold protein/0.450
4isg1FYGlucokinase2.7.1.20.450
4msg2C6Tankyrase-12.4.2.300.450
4s1iPLPPyridoxal kinase, putative/0.450
1bk0ACVIsopenicillin N synthase1.21.3.10.449
1bx0FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.449
1qtiGNTAcetylcholinesterase3.1.1.70.449
1rxjBNIStreptavidin/0.449
1u0hFOKAdenylate cyclase type 2/0.449
1u0hFOKAdenylate cyclase type 5/0.449
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.449
2oazI96Methionine aminopeptidase 2/0.449
2w3aTOPDihydrofolate reductase1.5.1.30.449
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.449
3b1dPLSBetaC-S lyase/0.449
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.449
3htjETEbrA repressor/0.449
3i9jAVVADP-ribosyl cyclase/cyclic ADP-ribose hydrolase3.2.2.60.449
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.449
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.449
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4n1gCEIObelin/0.449
4ts7ADPPurine phosphoribosyltransferase (GpT-1)/0.449
5k2aZMAAdenosine receptor A2a/0.449
1cq8PY6Aspartate aminotransferase2.6.1.10.448
1e1qADPATP synthase subunit beta, mitochondrial3.6.3.140.448
1ivrCBAAspartate aminotransferase, mitochondrial2.6.1.10.448
1jdzFMBPurine nucleoside phosphorylase/0.448
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.448
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.448
1uxnNAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase/0.448
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2bf7HBIPteridine reductase 11.5.1.330.448
2qw8NAPEugenol synthase 11.1.1.3180.448
2rqfJH3Hemolymph juvenile hormone binding protein/0.448
2tprFADTrypanothione reductase1.8.1.120.448
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3e92G6AMitogen-activated protein kinase 14/0.448
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3nxvD2FDihydrofolate reductase1.5.1.30.448
3pahXDEPhenylalanine-4-hydroxylase1.14.16.10.448
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4hshQEIQueuine tRNA-ribosyltransferase2.4.2.290.448
4qa0SHHHistone deacetylase 83.5.1.980.448
5cxv0HKMuscarinic acetylcholine receptor M1/0.448
3sn6P0GBeta-2 adrenergic receptor/0.448
1jlaTNKGag-Pol polyprotein2.7.7.490.447
1pq6965Oxysterols receptor LXR-beta/0.447
1wpgADPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.447
1xngDNDNH(3)-dependent NAD(+) synthetase6.3.1.50.447
2fs4PZ1Renin3.4.23.150.447
2hcdBIVVitamin D3 receptor A/0.447
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.447
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.447
3iogSDFMetallo-beta-lactamase type 2/0.447
3lfeZ84Mitogen-activated protein kinase 14/0.447
3nxoD2BDihydrofolate reductase1.5.1.30.447
4bfpSWYTankyrase-22.4.2.300.447
4c6zTLE3-oxoacyl-ACP synthase/0.447
4dbs0HVAldo-keto reductase family 1 member C3/0.447
4eqrCOACoenzyme A disulfide reductase/0.447
4paaTHGDimethylglycine dehydrogenase, mitochondrial1.5.8.40.447
4uugPXGBranched-chain amino acid aminotransferase, putative/0.447
5dozNDPJamJ/0.447
1gj5130Prothrombin3.4.21.50.446
1p33MTXPteridine reductase 11.5.1.330.446
1p8dCO1Oxysterols receptor LXR-beta/0.446
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.446
1towCRZFatty acid-binding protein, adipocyte/0.446
1w6rGNTAcetylcholinesterase3.1.1.70.446
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.446
2fxuBIDActin, alpha skeletal muscle/0.446
2j3qTFLAcetylcholinesterase3.1.1.70.446
2j9gADPBiotin carboxylase6.3.4.140.446
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.446
2wksCB63-dehydroquinate dehydratase4.2.1.100.446
3gyf51PDihydrofolate reductase1.5.1.30.446
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
3mauPLRPutative sphingosine-1-phosphate lyase/0.446
3p9tTCLRepressor/0.446
3zlmANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.446
4b4vL34Bifunctional protein FolD/0.446
4eqrFADCoenzyme A disulfide reductase/0.446
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4xoqF42Coenzyme F420:L-glutamate ligase/0.446
1dhfFOLDihydrofolate reductase1.5.1.30.445
1gtrATPGlutamine--tRNA ligase6.1.1.180.445
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.445
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
1votHUPAcetylcholinesterase3.1.1.70.445
1yslCOAHydroxymethylglutaryl-CoA synthase2.3.3.100.445
2c3oTPPPyruvate synthase/0.445
2gevCOKPantothenate kinase2.7.1.330.445
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
2zs9ADPPantothenate kinase2.7.1.330.445
3dd125DGlycogen phosphorylase, liver form2.4.1.10.445
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.445
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3rgaILDEpoxide hydrolase LasB5.5.10.445
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.445
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.445
4dbw511Aldo-keto reductase family 1 member C3/0.445
4dhyS41Glucokinase2.7.1.20.445
4gt8ADPSensor protein VraS2.7.13.30.445
4qa2SHHHistone deacetylase 83.5.1.980.445
4qii2NE1,4-dihydroxy-2-naphthoyl-CoA synthase/0.445
4tmcFMNOld yellow enzyme/0.445
5esdTDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.445
1iayAVG1-aminocyclopropane-1-carboxylate synthase 24.4.1.140.444
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
1ysiN3BBcl-2-like protein 1/0.444
1yw9A84Methionine aminopeptidase 2/0.444
1zgbA1EAcetylcholinesterase3.1.1.70.444
2cy2ACOProbable acetyltransferase/0.444
2r2mI50Prothrombin3.4.21.50.444
2re8GSUGlutamine--tRNA ligase6.1.1.180.444
2x1eX1EAcyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form2.3.1.1640.444
2zhf49UProthrombin3.4.21.50.444
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.444
3pm1ETHTH-type transcriptional regulator QacR/0.444
4bfzZVZPantothenate kinase2.7.1.330.444
4bquCLRJapanin/0.444
4fal0T0Aldo-keto reductase family 1 member C3/0.444
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.444
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.444
1dljUGAUDP-glucose 6-dehydrogenase/0.443
1e2nRCAThymidine kinase/0.443
1fnbFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.443
2dw4FADLysine-specific histone demethylase 1A10.443
2ji9ADPOxalyl-CoA decarboxylase4.1.1.80.443
2pksG44Prothrombin3.4.21.50.443
2wnbC5PCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 12.4.99.40.443
2xupTZ5Acetylcholinesterase3.1.1.70.443
2xvv9DNSerum albumin/0.443
3eon341Glutaryl-CoA dehydrogenase/0.443
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
3ihgVAKAklavinone 12-hydroxylase RdmE/0.443
4a6eASEAcetylserotonin O-methyltransferase2.1.1.40.443
4fl0PLPAminotransferase ALD1, chloroplastic2.6.10.443
4ia05BBcGMP-specific 3',5'-cyclic phosphodiesterase/0.443
4mrxCZHObelin/0.443
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
5d7pAR6NAD-dependent protein deacetylase sirtuin-23.5.10.443
3rfmCFFAdenosine receptor A2a/0.443
1e79ADPATP synthase subunit alpha, mitochondrial/0.442
1e79ADPATP synthase subunit beta, mitochondrial3.6.3.140.442
1ej3CZHAequorin-2/0.442
1mvsDTMDihydrofolate reductase1.5.1.30.442
2ffqGSPRas-related protein Rab-6B/0.442
2jlcTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.442
2wggTLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.442
2xuoTZ4Acetylcholinesterase3.1.1.70.442
2yac937Serine/threonine-protein kinase PLK12.7.11.210.442
3n39FMNProtein NrdI/0.442
3qpg3QPAspartate aminotransferase2.6.1.10.442
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.442
4h6rFDAProline dehydrogenase/0.442
4nbiD3YD-tyrosyl-tRNA(Tyr) deacylase/0.442
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.442
1a9cGTPGTP cyclohydrolase 13.5.4.160.441
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.441
1mxfMTXPutative pteridine reductase 2/0.441
1u1cBAUUridine phosphorylase2.4.2.30.441
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
1ykdCMPAdenylate cyclase/0.441
1zgcA2EAcetylcholinesterase3.1.1.70.441
2ea2F77Methionine aminopeptidase 2/0.441
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3g6zA7TRenin3.4.23.150.441
3gx9TXDMorphinone reductase/0.441
3ipuO40Oxysterols receptor LXR-alpha/0.441
3qdzPRO_ALA_PRO_ARGProthrombin3.4.21.50.441
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
4bfuZVUPantothenate kinase2.7.1.330.441
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.441
4jxzATPGlutamine--tRNA ligase6.1.1.180.441
4xo7NAPAldo-keto reductase family 1 member C2/0.441
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.441
1a8t061Metallo-beta-lactamase type 2/0.440
1cq6PY4Aspartate aminotransferase2.6.1.10.440
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1h8hADPATP synthase subunit alpha, mitochondrial/0.440
1h8hADPATP synthase subunit beta, mitochondrial3.6.3.140.440
1ndjBTNStreptavidin/0.440
1t2cNAIL-lactate dehydrogenase1.1.1.270.440
1t7o152Carnitine O-acetyltransferase2.3.1.70.440
2a9y26AAdenosine kinase2.7.1.200.440
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.440
3dokGWJPol protein/0.440
3lzzGDPUncharacterized protein/0.440
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.440
3o9lLPNRenin3.4.23.150.440
3p0hFSEPutative tyrosyl-tRNA synthetase/0.440
3rj0BLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.440
3te4ACODopamine N-acetyltransferase/0.440
3u9y09LTankyrase-22.4.2.300.440
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.440
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.440
4iyg1HUStrictosidine synthase4.3.3.20.440
4j7hTRHPCZA361.3/0.440
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.440
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.440