Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4rw6494Gag-Pol polyprotein2.7.7.49

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4rw6494Gag-Pol polyprotein2.7.7.491.000
4rw4494Gag-Pol polyprotein2.7.7.490.636
4h4o506Gag-Pol polyprotein2.7.7.490.564
3is9AC7Gag-Pol polyprotein2.7.7.490.548
3t1a5MAGag-Pol polyprotein2.7.7.490.545
4h4m494Gag-Pol polyprotein2.7.7.490.537
3c6uM22Gag-Pol polyprotein2.7.7.490.536
4mfb29TGag-Pol polyprotein2.7.7.490.534
3c6tM14Gag-Pol polyprotein2.7.7.490.530
3dmjGWEPol protein/0.519
3dokGWJPol protein/0.512
2wonZZEGag-Pol polyprotein2.7.7.490.507
3dleGFAGag-Pol polyprotein2.7.7.490.499
3drpR8EGag-Pol polyprotein2.7.7.490.493
2be2R22Gag-Pol polyprotein2.7.7.490.492
3drrR8EGag-Pol polyprotein2.7.7.490.490
2jleI15Reverse transcriptase/RNaseH/0.487
2b5j3ACGag-Pol polyprotein2.7.7.490.484
3lalKRVGag-Pol polyprotein2.7.7.490.484
3t195MAGag-Pol polyprotein2.7.7.490.479
3qlhT27Gag-Pol polyprotein2.7.7.490.475
4lsl1YQGag-Pol polyprotein2.7.7.490.467
1c1bGCAGag-Pol polyprotein2.7.7.490.465
3tamM06Gag-Pol polyprotein2.7.7.490.460
3dlgGWEGag-Pol polyprotein2.7.7.490.454
4i2pG73Gag-Pol polyprotein2.7.7.490.451
4id5T27Gag-Pol polyprotein2.7.7.490.451
3bgrT27Gag-Pol polyprotein2.7.7.490.450
3nbpJGZGag-Pol polyprotein2.7.7.490.450
3lakKR1Gag-Pol polyprotein2.7.7.490.443