sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4rts	SAM	DNA adenine methylase	2.1.1.72

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4rts	SAM	DNA adenine methylase	2.1.1.72	1.000
4rtm	SAM	DNA adenine methylase	2.1.1.72	0.584
2ore	SAH	DNA adenine methylase	2.1.1.72	0.583
4gbe	SAH	DNA adenine methylase	2.1.1.72	0.575
2g1p	SAH	DNA adenine methylase	2.1.1.72	0.572
4rtj	SFG	DNA adenine methylase	2.1.1.72	0.559
4rtl	SFG	DNA adenine methylase	2.1.1.72	0.553
4rtk	SAH	DNA adenine methylase	2.1.1.72	0.523
4gol	SA8	DNA adenine methylase	2.1.1.72	0.522
4rtr	SAM	DNA adenine methylase	2.1.1.72	0.503
2dpm	SAM	Modification methylase DpnIIA	2.1.1.72	0.489
4rto	SFG	DNA adenine methylase	2.1.1.72	0.483
4rtn	SAH	DNA adenine methylase	2.1.1.72	0.462