scPDB - Distribution of Cavity Similarity values of 4rto entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4rto	SFG	DNA adenine methylase	2.1.1.72

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
4rto	SFG	DNA adenine methylase	2.1.1.72	1.000
4rts	SAM	DNA adenine methylase	2.1.1.72	0.703
4rtn	SAH	DNA adenine methylase	2.1.1.72	0.691
4rtl	SFG	DNA adenine methylase	2.1.1.72	0.624
4gol	SA8	DNA adenine methylase	2.1.1.72	0.621
4rtr	SAM	DNA adenine methylase	2.1.1.72	0.614
2ore	SAH	DNA adenine methylase	2.1.1.72	0.610
4rtm	SAM	DNA adenine methylase	2.1.1.72	0.610
4rtk	SAH	DNA adenine methylase	2.1.1.72	0.600
4gbe	SAH	DNA adenine methylase	2.1.1.72	0.597
2g1p	SAH	DNA adenine methylase	2.1.1.72	0.584
4rtq	SAH	DNA adenine methylase	2.1.1.72	0.574
4rtp	SAM	DNA adenine methylase	2.1.1.72	0.564
2dpm	SAM	Modification methylase DpnIIA	2.1.1.72	0.552
4rtj	SFG	DNA adenine methylase	2.1.1.72	0.528
1boo	SAH	Modification methylase PvuII	2.1.1.113	0.521
1nw5	SAM	Modification methylase RsrI	2.1.1.72	0.505
4h0n	SAH	Dnmt2	/	0.505
3pt9	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.491
4anx	534	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.489
9mht	SAH	Modification methylase HhaI	2.1.1.37	0.479
1fjx	SAH	Modification methylase HhaI	2.1.1.37	0.477
3v97	SAH	Ribosomal RNA large subunit methyltransferase K/L	2.1.1.173	0.476
3v8v	SAM	Ribosomal RNA large subunit methyltransferase K/L	2.1.1.173	0.475
3swr	SFG	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.472
3tlj	SAH	Uncharacterized protein	/	0.471
1nw6	SFG	Modification methylase RsrI	2.1.1.72	0.470
2ih2	NEA	Modification methylase TaqI	2.1.1.72	0.470
3ldf	SAH	Uncharacterized protein	/	0.470
3qv2	SAH	5-cytosine DNA methyltransferase	/	0.468
1eji	THF	Serine hydroxymethyltransferase, cytosolic	/	0.466
2po7	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.465
3tm4	SAM	Uncharacterized protein	/	0.462
2zif	SAM	Methyltransferase	/	0.459
2hmy	SAM	Modification methylase HhaI	2.1.1.37	0.458
2ibt	NEA	Modification methylase TaqI	2.1.1.72	0.458
5fa8	SAM	Ribosomal protein L11 methyltransferase, putative	/	0.458
3tm5	SFG	Uncharacterized protein	/	0.456
8mht	SAH	Modification methylase HhaI	2.1.1.37	0.456
4u7t	SAH	DNA (cytosine-5)-methyltransferase 3A	2.1.1.37	0.454
3pt6	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.453
7mht	SAH	Modification methylase HhaI	2.1.1.37	0.453
10mh	SAH	Modification methylase HhaI	2.1.1.37	0.452
4da4	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.451
2eg5	SAH	7-methylxanthosine synthase 1	/	0.448
3ldg	SAH	Uncharacterized protein	/	0.446
1eg2	MTA	Modification methylase RsrI	2.1.1.72	0.445
1yf3	SAH	DNA adenine methylase	/	0.444
3dmh	SAM	Probable ribosomal RNA small subunit methyltransferase	/	0.444
3nw9	637	Catechol O-methyltransferase	2.1.1.6	0.443
1mht	SAH	Modification methylase HhaI	2.1.1.37	0.442
1nbi	SAM	Glycine N-methyltransferase	2.1.1.20	0.442
4ft4	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.442
5e72	SAM	N2, N2-dimethylguanosine tRNA methyltransferase	/	0.442
1qrp	HH0	Pepsin A-4	3.4.23.1	0.441
1rx7	FOL	Dihydrofolate reductase	1.5.1.3	0.441
3vas	ADN	Putative adenosine kinase	/	0.441
2z3u	CRR	Cytochrome P450	/	0.440
3ely	SAH	Methyltransferase	/	0.440