sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4rrc | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4rrc | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 1.000 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.636 | |
| 4rrb | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.627 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.627 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.621 | |
| 4rrd | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.619 | |
| 4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.619 | |
| 4rr9 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.617 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.615 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.611 | |
| 4rrl | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.610 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.603 | |
| 4rrk | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.592 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.578 | |
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.548 | |
| 4rrq | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.542 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.537 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.533 | |
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.532 | |
| 4rrj | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.527 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.522 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.518 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.516 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.515 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.508 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.503 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.499 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.495 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.492 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.492 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.492 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.491 | |
| 2xvw | 9NR | Serum albumin | / | 0.489 | |
| 4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.486 | |
| 2rh1 | CAU | Beta-2 adrenergic receptor | / | 0.485 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.483 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.483 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.482 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.482 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.482 | |
| 5c4c | UPG | Histo-blood group ABO system transferase | / | 0.481 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.478 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.477 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.476 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.475 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.475 | |
| 2xvv | 9DN | Serum albumin | / | 0.474 | |
| 3ew2 | BTN | Hypothetical conserved protein | / | 0.474 | |
| 3glu | LYS_VAL_MET | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.473 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.473 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.473 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.472 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.472 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.472 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.472 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.472 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.471 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.471 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.469 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.469 | |
| 3pd5 | TSB | Threonine--tRNA ligase | 6.1.1.3 | 0.469 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.469 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.469 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.468 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.467 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.467 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.467 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.467 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.466 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.466 | |
| 3vf9 | 477 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.466 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.465 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.465 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.464 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.464 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.464 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.464 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.464 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.464 | |
| 2bxq | IMN | Serum albumin | / | 0.463 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.463 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.463 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.463 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.463 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.463 | |
| 4kxj | P34 | Nucleoprotein | / | 0.463 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.463 | |
| 3b9l | AZZ | Serum albumin | / | 0.462 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 2pvk | P45 | Casein kinase II subunit alpha | 2.7.11.1 | 0.461 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 3iog | SDF | Metallo-beta-lactamase type 2 | / | 0.461 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.461 | |
| 1ppj | ANY | Cytochrome b | / | 0.460 | |
| 2zul | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.460 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.460 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.459 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 2imf | TOM | 2-hydroxychromene-2-carboxylate isomerase | 5.99.1.4 | 0.458 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.458 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.458 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.458 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.457 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.457 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.457 | |
| 3fpj | SAM | Uncharacterized protein | / | 0.457 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.457 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.457 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.457 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.456 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.456 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.456 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.456 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.456 | |
| 4mbs | MRV | C-C chemokine receptor type 5 | / | 0.456 | |
| 4y1b | NAP | AntE | / | 0.456 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.456 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.455 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.455 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.455 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.455 | |
| 1ddt | APU | Diphtheria toxin | / | 0.454 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.454 | |
| 1swt | BTN | Streptavidin | / | 0.454 | |
| 3nhy | A7B | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.454 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.453 | |
| 2jfz | 003 | Glutamate racemase | / | 0.453 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 4nbi | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.453 | |
| 3d4s | TIM | Beta-2 adrenergic receptor | / | 0.453 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.452 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.452 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1osv | CHC | Bile acid receptor | / | 0.452 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.452 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.452 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.452 | |
| 2zwv | SAH | Probable ribosomal RNA small subunit methyltransferase | / | 0.452 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.452 | |
| 3up3 | XCA | aceDAF-12 | / | 0.452 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.452 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4amj | CVD | Beta-1 adrenergic receptor | / | 0.452 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.452 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.452 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.451 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.451 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.451 | |
| 1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.451 | |
| 3dmh | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.451 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3hy3 | 10F | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.451 | |
| 3n6u | TSU | HTH-type transcriptional regulator TsaR | / | 0.451 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 5dg3 | U21 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase | / | 0.451 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.450 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.450 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.450 | |
| 4bz8 | J38 | Histone deacetylase | / | 0.450 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.450 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.450 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.449 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.449 | |
| 1s36 | CEI | Obelin | / | 0.449 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.449 | |
| 2y01 | Y00 | Beta-1 adrenergic receptor | / | 0.449 | |
| 3dtc | VIN | Mitogen-activated protein kinase kinase kinase 9 | 2.7.11.25 | 0.449 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.449 | |
| 3zsv | ZSV | Integrase | / | 0.449 | |
| 4ceb | ZSV | Integrase | / | 0.449 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.449 | |
| 1fml | RTL | Retinol dehydratase | / | 0.448 | |
| 2bp1 | NDP | Aflatoxin B1 aldehyde reductase member 2 | / | 0.448 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.448 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.448 | |
| 3qzh | X69 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.448 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.448 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.448 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.448 | |
| 4xwt | U5P | Ribonuclease J | / | 0.448 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.447 | |
| 2bxm | IMN | Serum albumin | / | 0.447 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.447 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.447 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.447 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.447 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.447 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.447 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.447 | |
| 4kvz | SAH | PtnL protein | / | 0.447 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.447 | |
| 5dif | GNP | GTP-binding nuclear protein Ran | / | 0.447 | |
| 5d5b | CAU | Beta-2 adrenergic receptor | / | 0.447 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.447 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.446 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.446 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.446 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.446 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.446 | |
| 3uxh | UXH | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.446 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.446 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.446 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.445 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.445 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.445 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.445 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3inr | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.445 | |
| 3nhu | M42 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 3nhw | ZXZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.445 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.444 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.444 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.444 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.444 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.444 | |
| 1zdw | FLV | Prenyltransferase | / | 0.444 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.444 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.444 | |
| 3gy9 | COA | GCN5-related N-acetyltransferase | / | 0.444 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 3zr7 | OR8 | Progesterone receptor | / | 0.444 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.444 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.444 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.444 | |
| 5fsx | ADP | Uncharacterized protein | / | 0.444 | |
| 4ami | G90 | Beta-1 adrenergic receptor | / | 0.444 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.443 | |
| 1nw6 | SFG | Modification methylase RsrI | 2.1.1.72 | 0.443 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.443 | |
| 2r4u | ADP | Glycogen synthase | 2.4.1.21 | 0.443 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.443 | |
| 3btj | DEQ | HTH-type transcriptional regulator QacR | / | 0.443 | |
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.443 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.443 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.443 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.443 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.443 | |
| 5i2h | AGI | O-methyltransferase family 2 | / | 0.443 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.443 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.443 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.443 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.442 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.442 | |
| 2q16 | ITT | dITP/XTP pyrophosphatase | / | 0.442 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.442 | |
| 3bej | MUF | Bile acid receptor | / | 0.442 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.442 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.442 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.441 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.441 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.441 | |
| 2ol4 | JPN | Enoyl-ACP reductase | / | 0.441 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2ywv | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | / | 0.441 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.441 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3p9t | TCL | Repressor | / | 0.441 | |
| 3pxy | JWS | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.441 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.441 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.441 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.441 | |
| 4hxs | 1A3 | Bromodomain-containing protein 4 | / | 0.441 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
| 4u7w | NDP | MxaA | / | 0.441 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1wc0 | APC | Adenylate cyclase | / | 0.440 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.440 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.440 |