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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.11.000
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.757
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.724
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.712
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.670
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.639
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.625
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.625
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.623
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.619
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.616
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.616
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.616
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.613
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.602
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.601
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.600
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.599
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.598
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.597
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.597
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.595
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.593
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.585
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.583
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.581
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.577
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.575
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.571
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.570
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.569
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.568
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.567
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.566
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.563
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.563
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.562
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.562
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.561
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.560
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.559
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.559
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.557
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.556
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.554
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.554
2hog710Serine/threonine-protein kinase Chk12.7.11.10.553
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.553
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.552
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.552
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.552
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.551
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.550
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.549
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.549
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.548
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.548
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.547
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.545
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.545
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.543
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.543
3pxkPXKFocal adhesion kinase 12.7.10.20.543
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.542
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.542
3t8oATPRhodopsin kinase/0.542
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.541
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.541
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.540
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.539
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.539
3c4xATPRhodopsin kinase/0.538
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.538
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.537
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.536
5auwQUEDeath-associated protein kinase 12.7.11.10.535
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.534
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.533
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.533
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.532
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.532
2j0lANPFocal adhesion kinase 12.7.10.20.530
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.529
3zh8C58Protein kinase C iota type2.7.11.130.527
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.526
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.525
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.525
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.525
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.524
4fob0USALK tyrosine kinase receptor2.7.10.10.524
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.524
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.524
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.523
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.522
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.522
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.521
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.521
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.520
3c4wATPRhodopsin kinase/0.520
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.520
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.519
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.519
2j0m4STFocal adhesion kinase 12.7.10.20.518
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.518
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.518
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.517
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.517
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.517
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.516
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.514
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.514
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.513
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.513
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.513
2wxvWXVCyclin-dependent kinase 22.7.11.220.513
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.513
3tnwF18Cyclin-dependent kinase 22.7.11.220.513
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.513
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.511
3c4zADPRhodopsin kinase/0.510
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.509
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.509
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.509
2vgoAD5Aurora kinase B-A2.7.11.10.508
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.508
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.508
2acxANPG protein-coupled receptor kinase 62.7.11.160.507
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.507
5av2KMPDeath-associated protein kinase 12.7.11.10.507
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.506
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.506
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.506
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.506
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.505
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.505
3a7hATPSerine/threonine-protein kinase 242.7.11.10.505
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.505
4fv6E57Mitogen-activated protein kinase 12.7.11.240.505
5auvAGIDeath-associated protein kinase 12.7.11.10.505
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.504
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.504
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.504
2qo9ANPEphrin type-A receptor 32.7.10.10.503
4gk2L66Ephrin type-A receptor 32.7.10.10.503
1bygSTUTyrosine-protein kinase CSK/0.502
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.502
2ijmATPFocal adhesion kinase 12.7.10.20.501
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.501
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.500
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.500
3zep1NXTyrosine-protein kinase JAK32.7.10.20.500
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.500
4qo9627Serine/threonine-protein kinase 242.7.11.10.500
2etm7PYFocal adhesion kinase 12.7.10.20.499
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.499
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.499
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.498
1e9hINRCyclin-dependent kinase 22.7.11.220.497
3i60E86Mitogen-activated protein kinase 12.7.11.240.497
3my5RFZCyclin-dependent kinase 22.7.11.220.497
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.497
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.497
3gu6ADPDeath-associated protein kinase 12.7.11.10.496
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.496
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.495
1u54ACPActivated CDC42 kinase 1/0.494
2x1nX1NCyclin-dependent kinase 22.7.11.220.494
4l9i8PRRhodopsin kinase/0.494
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.493
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.493
4wboANWRhodopsin kinase/0.493
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.493
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.492
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.492
4fod0UVALK tyrosine kinase receptor2.7.10.10.492
4qmzB49Serine/threonine-protein kinase 242.7.11.10.492
5aaaVGHALK tyrosine kinase receptor2.7.10.10.492
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.491
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.491
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.491
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.491
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.491
4k8aK8AFocal adhesion kinase 12.7.10.20.491
1zys199Serine/threonine-protein kinase Chk12.7.11.10.490
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.490
2wipP49Cyclin-dependent kinase 22.7.11.220.490
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.490
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.490
3ztxZTXAurora kinase B-A2.7.11.10.490
4b99R4LMitogen-activated protein kinase 72.7.11.240.490
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.490
4gk3L87Ephrin type-A receptor 32.7.10.10.490
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.489
2xb7GUIALK tyrosine kinase receptor2.7.10.10.489
3sheI85MAP kinase-activated protein kinase 32.7.11.10.489
4gmy0X5Tyrosine-protein kinase JAK2/0.489
1aq1STUCyclin-dependent kinase 22.7.11.220.488
1xjdSTUProtein kinase C theta type2.7.11.130.488
2i40BLZCyclin-dependent kinase 22.7.11.220.488
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.488
3a62STURibosomal protein S6 kinase beta-12.7.11.10.488
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.488
4a9tA9TSerine/threonine-protein kinase Chk22.7.11.10.488
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.488
1pjkANPCasein kinase II subunit alpha2.7.11.10.487
2ijmADPFocal adhesion kinase 12.7.10.20.487
2yaaATPDeath-associated protein kinase 2/0.487
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.487
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.487
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
1zrzBI1Protein kinase C iota type2.7.11.130.486
4qnaX11Serine/threonine-protein kinase 242.7.11.10.486
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.485
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.485
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.485
4fv9E71Mitogen-activated protein kinase 12.7.11.240.485
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.484
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.484
2in6839Wee1-like protein kinase2.7.10.20.484
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.484
3bqr4RBDeath-associated protein kinase 3/0.484
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.484
5av4GENDeath-associated protein kinase 12.7.11.10.484
5e8xSTUTGF-beta receptor type-12.7.11.300.484
2jkqVG8Focal adhesion kinase 12.7.10.20.483
3c50ADPRhodopsin kinase/0.483
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.483
1fvv107Cyclin-dependent kinase 22.7.11.220.482
1pkdUCNCyclin-dependent kinase 22.7.11.220.482
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.482
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.482
4fv8E63Mitogen-activated protein kinase 12.7.11.240.482
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.481
2vd5BI8Myotonin-protein kinase2.7.11.10.481
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.481
3igoANPCalmodulin-domain protein kinase 1, putative/0.481
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.481
5aacVGHALK tyrosine kinase receptor2.7.10.10.481
2bfyH1NAurora kinase B-A2.7.11.10.480
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.480
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.480
2x9fX9FEphrin type-B receptor 42.7.10.10.480
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.480
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.480
2izuP01Casein kinase I isoform gamma-32.7.11.10.479
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.479
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.479
4fyn0VETyrosine-protein kinase SYK2.7.10.20.479
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.479
1jpaANPEphrin type-B receptor 22.7.10.10.478
2itnANPEpidermal growth factor receptor2.7.10.10.478
2wihP48Cyclin-dependent kinase 22.7.11.220.478
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.478
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.477
2pvnP63Casein kinase II subunit alpha2.7.11.10.477
3ggfGVDSerine/threonine-protein kinase 26/0.477
3lltANPProtein serine/threonine kinase-1/0.477
2xvdAS6Ephrin type-B receptor 42.7.10.10.476
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3qc9ADPRhodopsin kinase/0.475
4foc0UUALK tyrosine kinase receptor2.7.10.10.475
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.475
2bkzSBCCyclin-dependent kinase 22.7.11.220.474
2y6o1N1Ephrin type-A receptor 42.7.10.10.474
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.474
3w551FMMitogen-activated protein kinase 12.7.11.240.474
4b8lA0PAurora kinase B-A2.7.11.10.474
4gg70J8Hepatocyte growth factor receptor2.7.10.10.474
4nj32KDCyclin-dependent kinase 22.7.11.220.474
5av047XDeath-associated protein kinase 12.7.11.10.474
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.473
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.473
1py5PY1TGF-beta receptor type-12.7.11.300.472
2ittAEEEpidermal growth factor receptor2.7.10.10.472
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.472
2yn8STUEphrin type-B receptor 42.7.10.10.472
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
3bhtMFRCyclin-dependent kinase 22.7.11.220.472
3gubGUBDeath-associated protein kinase 12.7.11.10.472
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.472
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.472
5aabVGHALK tyrosine kinase receptor2.7.10.10.472
3at4CCKCasein kinase II subunit alpha2.7.11.10.471
2c4g514Cyclin-dependent kinase 22.7.11.220.470
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.470
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.470
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.470
3op5REBSerine/threonine-protein kinase VRK12.7.11.10.470
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.470
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.470
4grb0XGCasein kinase II subunit alpha2.7.11.10.470
1mp8ADPFocal adhesion kinase 12.7.10.20.469
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.469
2izrBRKCasein kinase I isoform gamma-32.7.11.10.469
3bhy7CPDeath-associated protein kinase 3/0.469
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.469
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.469
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.468
4brxKGWFocal adhesion kinase 12.7.10.20.468
4fmqANPMitogen-activated protein kinase 12.7.11.240.468
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.468
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.468
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.467
2izt23DCasein kinase I isoform gamma-32.7.11.10.467
2qoqANPEphrin type-A receptor 32.7.10.10.467
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.467
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.467
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.467
4bcmT7ZCyclin-dependent kinase 22.7.11.220.467
4ccbOFGALK tyrosine kinase receptor2.7.10.10.467
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.467
4jbqVX6Aurora kinase A2.7.11.10.467
5e8ySTUTGF-beta receptor type-22.7.11.300.467
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.466
3lctADPALK tyrosine kinase receptor2.7.10.10.466
4gu610NFocal adhesion kinase 12.7.10.20.466
5dr2ATPAurora kinase A2.7.11.10.466
1m2pHNACasein kinase II subunit alpha2.7.11.10.465
1oiyN41Cyclin-dependent kinase 22.7.11.220.465
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.465
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.465
4g2fC07Ephrin type-A receptor 32.7.10.10.465
4hvi19STyrosine-protein kinase JAK32.7.10.20.465
4jqeANPCasein kinase II subunit alpha2.7.11.10.465
4qmlANPSerine/threonine-protein kinase 242.7.11.10.465
4yuqKS1Calmodulin-like domain protein kinase/0.465
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.464
3qyw6PBMitogen-activated protein kinase 12.7.11.240.464
3uyt0CKCasein kinase I isoform delta2.7.11.10.464
4kbk1QGCasein kinase I isoform delta2.7.11.10.464
4riyADPEpidermal growth factor receptor2.7.10.10.464
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.463
2xp2VGHALK tyrosine kinase receptor2.7.10.10.463
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.463
3zdu38RCyclin-dependent kinase-like 32.7.11.220.463
4aguD15Cyclin-dependent kinase-like 1/0.463
4c3pACPAurora kinase A2.7.11.10.463
4dpuAGSMevalonate diphosphate decarboxylase/0.463
4dtaADNAPH(2'')-Id/0.463
4loqSB4Mitogen-activated protein kinase 14/0.463
5e92ANPTGF-beta receptor type-22.7.11.300.463
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.462
2itpAEEEpidermal growth factor receptor2.7.10.10.462
4iwd1JCHepatocyte growth factor receptor2.7.10.10.462
4wkqIREEpidermal growth factor receptor2.7.10.10.462
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.461
2ckeIQUDeath-associated protein kinase 2/0.461
2oji33AMitogen-activated protein kinase 12.7.11.240.461
2vx17X8Ephrin type-B receptor 42.7.10.10.461
3bheBZNGag-Pol polyprotein3.4.23.160.461
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.461
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.461
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.461
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.461
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.461
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.461
5e8wSTUTGF-beta receptor type-12.7.11.300.461
1m2rMNYCasein kinase II subunit alpha2.7.11.10.460
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.460
2cchATPCyclin-dependent kinase 22.7.11.220.460
2csnCKICasein kinase I homolog 12.7.11.10.460
2xneASHAurora kinase A2.7.11.10.460
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.460
3umw596Serine/threonine-protein kinase pim-12.7.11.10.460
4eomATPCyclin-dependent kinase 22.7.11.220.460
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.460
4ix6ADPUncharacterized protein/0.460
1ol7ADPAurora kinase A2.7.11.10.459
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.459
2qo7ANPEphrin type-A receptor 32.7.10.10.459
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.459
4c61LMMTyrosine-protein kinase JAK2/0.459
4d58BI9Focal adhesion kinase 12.7.10.20.459
4j95ACPFibroblast growth factor receptor 2/0.459
4y95746Tyrosine-protein kinase/0.459
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.458
1wvySTUDeath-associated protein kinase 12.7.11.10.458
2uzbC75Cyclin-dependent kinase 22.7.11.220.458
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.458
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.458
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.458
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.458
1tvoFRZMitogen-activated protein kinase 12.7.11.240.457
2j7t274Serine/threonine-protein kinase 102.7.11.10.457
2vwz7X6Ephrin type-B receptor 42.7.10.10.457
3eyhIZATyrosine-protein kinase JAK1/0.457
3gu5ANPDeath-associated protein kinase 12.7.11.10.457
3rk507ZCyclin-dependent kinase 22.7.11.220.457
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.457
4hgs15GCasein kinase I isoform gamma-32.7.11.10.457
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.456
1h1r6CPCyclin-dependent kinase 22.7.11.220.456
3nxe2NCProtease/0.456
4bb432WEphrin type-B receptor 42.7.10.10.456
4dgo0JWCasein kinase II subunit alpha2.7.11.10.456
1di8DTQCyclin-dependent kinase 22.7.11.220.455
1h1s4SPCyclin-dependent kinase 22.7.11.220.455
1jkkANPDeath-associated protein kinase 12.7.11.10.455
1vjy460TGF-beta receptor type-12.7.11.300.455
1w0xOLOCyclin-dependent kinase 22.7.11.220.455
2j0k4STFocal adhesion kinase 12.7.10.20.455
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.455
3ral04ZCyclin-dependent kinase 22.7.11.220.455
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.455
4a9rRU5Serine/threonine-protein kinase Chk22.7.11.10.455
4bdaVFBSerine/threonine-protein kinase Chk22.7.11.10.455
4dgnLU2Casein kinase II subunit alpha2.7.11.10.455
4k33ACPFibroblast growth factor receptor 32.7.10.10.455
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.454
1u3dFADCryptochrome-1/0.454
2bhhRYUCyclin-dependent kinase 22.7.11.220.454
2itvANPEpidermal growth factor receptor2.7.10.10.454
2vgpAD6Aurora kinase B-A2.7.11.10.454
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.454
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.454
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.454
4ysjADPCalmodulin-like domain protein kinase/0.454
5auxKMPDeath-associated protein kinase 12.7.11.10.454
5dt0SKEAurora kinase A2.7.11.10.454
1me8RVPInosine-5'-monophosphate dehydrogenase/0.453
2xikJ60Serine/threonine-protein kinase 252.7.11.10.453
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.453
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.453
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.453
3dfcANPDeath-associated protein kinase 12.7.11.10.453
3e5aVX6Aurora kinase A2.7.11.10.453
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.453
4bdeCWSSerine/threonine-protein kinase Chk22.7.11.10.453
4cd0AWJALK tyrosine kinase receptor2.7.10.10.453
4i22IREEpidermal growth factor receptor2.7.10.10.453
3sn6P0GBeta-2 adrenergic receptor/0.453
1bwsNDPGDP-L-fucose synthase/0.452
1unlRRCCyclin-dependent-like kinase 52.7.11.10.452
2uzlC94Cyclin-dependent kinase 22.7.11.220.452
2z2w770Wee1-like protein kinase2.7.10.20.452
2z7lS91Mitogen-activated protein kinase 12.7.11.240.452
3a8wATPProtein kinase C iota type2.7.11.130.452
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.452
4ix5ANPUncharacterized protein/0.452
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.452
1wvxBD4Death-associated protein kinase 12.7.11.10.451
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.451
3cbsR12Cellular retinoic acid-binding protein 2/0.451
3iok1P6Tyrosine-protein kinase JAK2/0.451
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.451
3rk708ZCyclin-dependent kinase 22.7.11.220.451
3uli1N3Cyclin-dependent kinase 22.7.11.220.451
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.451
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.451
5cvhADPCasein kinase II subunit alpha2.7.11.10.451
5dosATPAurora kinase A2.7.11.10.451
1c1dNAIPhenylalanine dehydrogenase/0.450
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.450
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.450
2wpa889Cyclin-dependent kinase 22.7.11.220.450
3a1nNADNDP-sugar epimerase/0.450
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.450
3q5iANPProtein kinase, putative/0.450
3r9hZ67Cyclin-dependent kinase 22.7.11.220.450
3zewSTUEphrin type-B receptor 42.7.10.10.450
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.450
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.450
4gu94GUFocal adhesion kinase 12.7.10.20.450
4lopSB4Mitogen-activated protein kinase 14/0.450
4y93746Tyrosine-protein kinase/0.450
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.449
1v0oINRCell division control protein 2 homolog2.7.11.220.449
3d7tSTUTyrosine-protein kinase CSK/0.449
3rvg17PTyrosine-protein kinase JAK2/0.449
4btjATPTau-tubulin kinase 12.7.11.10.449
4c02TAKActivin receptor type-12.7.11.300.449
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.449
4erkOLOMitogen-activated protein kinase 12.7.11.240.449
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.449
1g5sI17Cyclin-dependent kinase 22.7.11.220.448
1ol6ATPAurora kinase A2.7.11.10.448
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.448
2dwbANPAurora kinase A2.7.11.10.448
2vwy7X5Ephrin type-B receptor 42.7.10.10.448
3gggNADPrephenate dehydrogenase/0.448
4a6cQG9Gag-Pol polyprotein3.4.23.160.448
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.448
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.448
4i4e1BQFocal adhesion kinase 12.7.10.20.448
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
1eh4IC1Casein kinase I homolog 12.7.11.10.447
2c475IDCasein kinase I isoform gamma-2/0.447
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.447
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.447
3vf80JETyrosine-protein kinase SYK2.7.10.20.447
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.447
4h3qANPMitogen-activated protein kinase 12.7.11.240.447
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.447
5av3KMPDeath-associated protein kinase 12.7.11.10.447
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.446
2iw84SPCyclin-dependent kinase 22.7.11.220.446
2of4979Tyrosine-protein kinase Lck2.7.10.20.446
2vx07X7Ephrin type-B receptor 42.7.10.10.446
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.446
3q9xEMOCasein kinase II subunit alpha2.7.11.10.446
3rak03ZCyclin-dependent kinase 22.7.11.220.446
3rmf20ZCyclin-dependent kinase 22.7.11.220.446
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.445
3qt62P0Mevalonate diphosphate decarboxylase/0.445
3s2pPMUCyclin-dependent kinase 22.7.11.220.445
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.445
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.445
1cbqRE9Cellular retinoic acid-binding protein 2/0.444
2bujSTUSerine/threonine-protein kinase 16/0.444
2uzdC85Cyclin-dependent kinase 22.7.11.220.444
2wotZZGTGF-beta receptor type-12.7.11.300.444
2wqeADPAurora kinase A2.7.11.10.444
2yfxVGHALK tyrosine kinase receptor2.7.10.10.444
3tucFPWTyrosine-protein kinase SYK2.7.10.20.444
3u4uLNHCasein kinase II subunit alpha2.7.11.10.444
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.444
4cegADPAurora kinase A2.7.11.10.444
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.444
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.444
4fx360KCyclin-dependent kinase 22.7.11.220.444
4g3pUD1Bifunctional protein GlmU/0.444
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
5cshATPCasein kinase II subunit alpha2.7.11.10.444
1csnATPCasein kinase I homolog 12.7.11.10.443
2j0j4STFocal adhesion kinase 12.7.10.20.443
2uzeC95Cyclin-dependent kinase 22.7.11.220.443
2xngA0HAurora kinase A2.7.11.10.443
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.443
4fkw62KCyclin-dependent kinase 22.7.11.220.443
4gk4L90Ephrin type-A receptor 32.7.10.10.443
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.443
1mqbANPEphrin type-A receptor 22.7.10.10.442
2b7aIZATyrosine-protein kinase JAK2/0.442
2btrU73Cyclin-dependent kinase 22.7.11.220.442
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.442
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.442
4eooATPCyclin-dependent kinase 22.7.11.220.442
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.442
4hvh19RTyrosine-protein kinase JAK32.7.10.20.442
4i231C9Epidermal growth factor receptor2.7.10.10.442
4ifcADPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.442
4j97ACPFibroblast growth factor receptor 2/0.442
4jrnANPRhoptry kinase family protein/0.442
4n57ADPAPH(2'')-Id/0.442
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.442
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.441
2hk51BMTyrosine-protein kinase HCK2.7.10.20.441
2vwu7X1Ephrin type-B receptor 42.7.10.10.441
2xs0ANPMitogen-activated protein kinase 82.7.11.240.441
3kpkFADSulfide-quinone reductase/0.441
3uzp0CKCasein kinase I isoform delta2.7.11.10.441
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.441
4b8zNAPGDP-L-fucose synthase1.1.1.2710.441
4c57FEFCyclin-G-associated kinase2.7.11.10.441
4k9yK9YFocal adhesion kinase 12.7.10.20.441
1jvsNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.440
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.440
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.440
2c6tDT5Cyclin-dependent kinase 22.7.11.220.440
2eb3ANPEpidermal growth factor receptor2.7.10.10.440
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.440
3rkb12ZCyclin-dependent kinase 22.7.11.220.440
3upf0BUPolyprotein/0.440
4btjADPTau-tubulin kinase 12.7.11.10.440
4g6oE28Mitogen-activated protein kinase 12.7.11.240.440
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.440
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.440
5dt3ATPAurora kinase A2.7.11.10.440