sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 1.000 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.540 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.522 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.510 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.497 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.488 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.478 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.462 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.462 | |
| 4e2d | FMN | Dehydrogenase | / | 0.461 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.459 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.457 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.456 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 4e2b | FMN | Dehydrogenase | / | 0.452 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.451 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.449 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 |