sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4qpp	SAH	Protein arginine N-methyltransferase 6

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4qpp	SAH	Protein arginine N-methyltransferase 6	/	1.000
4c04	SFG	Protein arginine N-methyltransferase 6	/	0.628
4c05	SAH	Protein arginine N-methyltransferase 6	/	0.571
1ori	SAH	Protein arginine N-methyltransferase 1	/	0.555
4m37	SAH	Protein arginine N-methyltransferase 7	2.1.1	0.480
1orh	SAH	Protein arginine N-methyltransferase 1	/	0.458
3b3f	SAH	Histone-arginine methyltransferase CARM1	/	0.454
4q71	FAD	Bifunctional protein PutA	/	0.446
5bp9	SAH	Putative methyltransferase protein	/	0.446