sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4qkn	JMS	Alpha-ketoglutarate-dependent dioxygenase FTO

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4qkn	JMS	Alpha-ketoglutarate-dependent dioxygenase FTO	/	1.000
4ie0	PD2	Alpha-ketoglutarate-dependent dioxygenase FTO	/	0.587
4ie6	UN9	Alpha-ketoglutarate-dependent dioxygenase FTO	/	0.587
3lfm	3DT	Alpha-ketoglutarate-dependent dioxygenase FTO	/	0.577
4zs2	FLU	Alpha-ketoglutarate-dependent dioxygenase FTO	/	0.527
4ie5	MD6	Alpha-ketoglutarate-dependent dioxygenase FTO	/	0.523
3qk0	QK0	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.444