sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4q0k	GA3	Phytohormone-binding protein

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4q0k	GA3	Phytohormone-binding protein	/	1.000
2flh	ZEA	Cytokinin-specific binding protein	/	0.501
4eyw	L0R	Carnitine O-palmitoyltransferase 2, mitochondrial	2.3.1.21	0.462
2fw3	BUI	Carnitine O-palmitoyltransferase 2, mitochondrial	2.3.1.21	0.460
3em0	CHD	Fatty acid-binding protein 6, ileal (gastrotropin)	/	0.456
2whq	HI6	Acetylcholinesterase	3.1.1.7	0.450
1x1b	SAH	C-20 methyltransferase	/	0.448
4epl	JAI	Jasmonic acid-amido synthetase JAR1	6.3.2	0.445
4psb	GA3	Cytokinin-specific binding protein	/	0.444