sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4py0 | 6AT | P2Y purinoceptor 12 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4py0 | 6AT | P2Y purinoceptor 12 | / | 1.000 | |
| 4pxz | CLR | P2Y purinoceptor 12 | / | 0.603 | |
| 5dp2 | NAP | CurF | / | 0.533 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.501 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.486 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.484 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.484 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.483 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.481 | |
| 2hct | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.480 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.480 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.478 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 3eks | CY9 | Actin-5C | / | 0.476 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.475 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.475 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.475 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.474 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.473 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.473 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.473 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.473 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.473 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.472 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.472 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2ejz | SAH | Diphthine synthase | / | 0.471 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.471 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.471 | |
| 3kqj | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.471 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.471 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.470 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.470 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.469 | |
| 3dzj | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.469 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.469 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.468 | |
| 3eku | CY9 | Actin-5C | / | 0.468 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.468 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.468 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.467 | |
| 3hz6 | ADP | Xylulokinase | / | 0.467 | |
| 3irh | DTP | HD domain protein | / | 0.467 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.466 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.466 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.466 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.465 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.465 | |
| 3x02 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.465 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.465 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.464 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.464 | |
| 3nhl | YTR | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.464 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.464 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.464 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.463 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.463 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.462 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.461 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 1wua | AP8 | Actin, alpha skeletal muscle | / | 0.461 | |
| 2xls | NAP | Putative flavin-containing monooxygenase | / | 0.461 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.461 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.461 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.461 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.461 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.460 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.460 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.460 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.460 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.460 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.460 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.460 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.460 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.460 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.459 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.459 | |
| 3x0c | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.459 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.458 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.458 | |
| 3dz7 | O8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.458 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.458 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.458 | |
| 3vmm | P0D | Alanine--anticapsin ligase | / | 0.458 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4cef | D0T | Integrase | / | 0.458 | |
| 4dmg | SAM | Uncharacterized protein | / | 0.458 | |
| 4loc | BTN | Pyruvate carboxylase | / | 0.458 | |
| 4nbj | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.458 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.457 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.457 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.457 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.457 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.457 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 4gsu | DWZ | L,D-transpeptidase 2 | 2.3.2 | 0.457 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.456 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.456 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.456 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.456 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.456 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.456 | |
| 4jey | PLP | Acetylornithine/succinyldiaminopimelate aminotransferase | 2.6.1.11 | 0.456 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.456 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.455 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.455 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.455 | |
| 2g1a | 5HG | Class B acid phosphatase | 3.1.3.2 | 0.455 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2xvu | 9DN | Serum albumin | / | 0.455 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.455 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.455 | |
| 1lke | DOG | Bilin-binding protein | / | 0.454 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.454 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.454 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.454 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.454 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1xms | ANP | Protein RecA | / | 0.453 | |
| 2qxx | TTP | dCTP deaminase | 3.5.4.13 | 0.453 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.453 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.453 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.453 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.452 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.452 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.452 | |
| 4j7h | TRH | PCZA361.3 | / | 0.452 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 2rh1 | CAU | Beta-2 adrenergic receptor | / | 0.452 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.451 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.451 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 2pda | TPP | Pyruvate synthase | / | 0.451 | |
| 2qe2 | 452 | Polyprotein | / | 0.451 | |
| 2vxk | COA | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.451 | |
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.451 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.451 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.451 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.450 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.450 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.450 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.450 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.450 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.450 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 4hmx | FMN | Pyridoxamine 5'-phosphate oxidase | / | 0.450 | |
| 4ovi | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.450 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.450 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.449 | |
| 1m9n | AMZ | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.449 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.449 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.449 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.449 | |
| 2egl | SAH | Diphthine synthase | / | 0.449 | |
| 2vqz | MGT | Polymerase basic protein 2 | / | 0.449 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.449 | |
| 3bld | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.449 | |
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 0.449 | |
| 8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.448 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.448 | |
| 1dqa | COA | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.448 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.448 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.448 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.448 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.448 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.448 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3gx9 | TXD | Morphinone reductase | / | 0.448 | |
| 3wgn | GSP | Cell division protein FtsZ | / | 0.448 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.448 | |
| 4to2 | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.448 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.448 | |
| 1az2 | NAP | Aldose reductase | 1.1.1.21 | 0.447 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.447 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 2e91 | ZOL | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.447 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.447 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.447 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.447 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.447 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.447 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.447 | |
| 4lcn | GNG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.447 | |
| 4qfz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.447 | |
| 4zas | TYD | CalS13 | / | 0.447 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.446 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.446 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.446 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.446 | |
| 2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.446 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 3vgn | FNN | Steroid Delta-isomerase | 5.3.3.1 | 0.446 | |
| 3w5u | FAD | Ferredoxin | / | 0.446 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.446 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.446 | |
| 1cq6 | PY4 | Aspartate aminotransferase | 2.6.1.1 | 0.445 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.445 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.445 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.445 | |
| 2po3 | T4K | 4-dehydrase | / | 0.445 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2wn6 | NDP | ADP-ribosyltransferase enzymatic component | / | 0.445 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.445 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.445 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.445 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3hky | IX6 | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 3iex | GMP | Purine nucleoside phosphorylase | / | 0.445 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 3ndj | JHZ | Methyltransferase | / | 0.445 | |
| 3pft | FMN | Flavin reductase | / | 0.445 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.445 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 4bfd | 8T3 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.445 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.445 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.444 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.444 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.444 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.444 | |
| 2gz8 | F3F | Orf1a polyprotein | / | 0.444 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.444 | |
| 3anl | SYC | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.444 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.444 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.444 | |
| 3e23 | SAM | Uncharacterized protein | / | 0.444 | |
| 3kp4 | MII | Transcriptional regulator TcaR | / | 0.444 | |
| 3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.444 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.444 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 3up0 | D7S | aceDAF-12 | / | 0.444 | |
| 4ce9 | O3N | Integrase | / | 0.444 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.444 | |
| 4pmj | NAP | Putative oxidoreductase | / | 0.444 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.443 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.443 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.443 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.443 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.443 | |
| 3vi5 | M4M | Hematopoietic prostaglandin D synthase | / | 0.443 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4cgj | NZL | Integrase | / | 0.443 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.443 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.443 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 1til | ATP | Anti-sigma F factor | / | 0.442 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.442 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.442 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.442 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.442 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.442 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.442 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.442 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.442 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.442 | |
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.442 | |
| 3lth | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.442 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.442 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.442 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 4hs4 | FMN | Chromate reductase | / | 0.442 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.442 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.441 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1muu | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.441 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1ozq | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.441 | |
| 1qsn | COA | HAT A1 | / | 0.441 | |
| 2clf | F6F | Tryptophan synthase alpha chain | / | 0.441 | |
| 2e07 | SAH | Diphthine synthase | / | 0.441 | |
| 2e8q | SAH | Diphthine synthase | / | 0.441 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.441 | |
| 2kce | D16 | Thymidylate synthase | / | 0.441 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.441 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.441 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
| 3gts | D3M | DdmC | / | 0.441 | |
| 3kmy | D8Y | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3n9j | EAA | Glutathione S-transferase P | 2.5.1.18 | 0.441 | |
| 3o9p | MHI | Periplasmic murein peptide-binding protein | / | 0.441 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.441 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.441 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.441 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.441 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.441 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.441 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.441 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.441 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1jf0 | CZH | Obelin | / | 0.440 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1ppj | ANY | Cytochrome b | / | 0.440 | |
| 1qvu | PRL | HTH-type transcriptional regulator QacR | / | 0.440 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.440 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.440 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.440 | |
| 3cnp | SP7 | Polyamine oxidase FMS1 | / | 0.440 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.440 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.440 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4ceq | QCH | Integrase | / | 0.440 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.440 | |
| 4g5d | NDP | Prostaglandin F synthase | 1.1.1.188 | 0.440 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.440 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.440 | |
| 4j7g | TRH | PCZA361.3 | / | 0.440 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.440 | |
| 4z87 | GDP | Inosine-5'-monophosphate dehydrogenase | / | 0.440 | |
| 5doz | NDP | JamJ | / | 0.440 |