sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4poo | SAM | Putative RNA methylase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4poo | SAM | Putative RNA methylase | / | 1.000 | |
| 3lby | SAH | Uncharacterized protein | / | 0.538 | |
| 3eey | SAM | rRNA methylase | / | 0.534 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.467 | |
| 3qvx | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.456 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.454 | |
| 4l4x | NDP | AmphI | / | 0.451 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.450 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.449 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.449 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.449 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.447 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.446 | |
| 3kec | 3KE | Collagenase 3 | 3.4.24 | 0.446 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.445 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.444 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.441 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.441 |