sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4p6x	HCY	Glucocorticoid receptor

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4p6x	HCY	Glucocorticoid receptor	/	1.000
4udc	DEX	Glucocorticoid receptor	/	0.520
1p93	DEX	Glucocorticoid receptor	/	0.487
1f17	NAI	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.474
2hdh	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.473
1zuc	T98	Progesterone receptor	/	0.458
1lsj	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.450
1sr7	MOF	Progesterone receptor	/	0.449
1ya3	STR	Mineralocorticoid receptor	/	0.445
2ovm	AS0	Progesterone receptor	/	0.441