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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ogiR78Bromodomain-containing protein 4

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4ogiR78Bromodomain-containing protein 4/1.000
4bjx73BBromodomain-containing protein 4/0.665
4c66H4CBromodomain-containing protein 4/0.658
4hxs1A3Bromodomain-containing protein 4/0.658
4lrg1XBBromodomain-containing protein 4/0.658
4nqmY1ZBromodomain-containing protein 4/0.652
4mr41K0Bromodomain-containing protein 4/0.650
3aqaBYHBromodomain-containing protein 2/0.648
4qzsJQ1Bromodomain-containing protein 4/0.641
4alg1GHBromodomain-containing protein 2/0.640
4men25KBromodomain-containing protein 4/0.640
4hxr1A4Bromodomain-containing protein 4/0.636
4a9oA9OBromodomain-containing protein 2/0.635
4bw2UTHBromodomain-containing protein 4/0.635
4hby13FBromodomain-containing protein 4/0.635
4j0r1H2Bromodomain-containing protein 4/0.635
4bw39BMBromodomain-containing protein 4/0.633
4o74R78Bromodomain-containing protein 4/0.629
4bw1S5BBromodomain-containing protein 4/0.626
4a9nA9NBromodomain-containing protein 2/0.625
3zyu1GHBromodomain-containing protein 4/0.622
4c67L5SBromodomain-containing protein 4/0.622
4flpJQ1Bromodomain testis-specific protein/0.621
4hxn1A7Bromodomain-containing protein 4/0.620
4j3i1K0Bromodomain-containing protein 4/0.617
4j0s1H3Bromodomain-containing protein 4/0.616
2yelWSHBromodomain-containing protein 4/0.615
4mep24YBromodomain-containing protein 4/0.615
4lyw21QBromodomain-containing protein 4/0.612
4hxo1A6Bromodomain-containing protein 4/0.611
4lr61XABromodomain-containing protein 4/0.607
4aknS5BBromodomain-containing protein 2/0.605
4meq25OBromodomain-containing protein 4/0.605
4a9lP9LBromodomain-containing protein 4/0.603
4uyg73BBromodomain-containing protein 2/0.603
4uyf73BBromodomain-containing protein 2/0.593
4o71CPBBromodomain-containing protein 4/0.592
2yemWSHBromodomain-containing protein 4/0.589
4f3i0S6Bromodomain-containing protein 4/0.582
4hbw14ZBromodomain-containing protein 4/0.581
4alhA9PBromodomain-containing protein 2/0.579
4o701QKBromodomain-containing protein 4/0.571
4mr61K0Bromodomain-containing protein 2/0.569
4o78SAVBromodomain-containing protein 4/0.565
5bt52LOBromodomain-containing protein 2/0.563
4bw49B6Bromodomain-containing protein 4/0.560
4cfkLY2Bromodomain-containing protein 4/0.559
2ydwWSHBromodomain-containing protein 2/0.550
4nr52LLCREB-binding protein/0.549
4mr51K0Bromodomain-containing protein 2/0.548
4gpj0Q1Bromodomain-containing protein 4/0.544
5bt42LOBromodomain-containing protein 4/0.543
4meo25VBromodomain-containing protein 4/0.542
4py6R78Bromodomain protein, putative/0.540
2yekEAMBromodomain-containing protein 2/0.537
4cfl8DQBromodomain-containing protein 4/0.537
5dfcEAMBromodomain-containing protein 2/0.519
3svgODRBromodomain-containing protein 4/0.518
2rhrEMOPutative ketoacyl reductase1.3.10.508
3cgbCOACoenzyme A disulfide reductase/0.507
3owj1ELCasein kinase II subunit alpha2.7.11.10.506
4ir5IR5Bromodomain adjacent to zinc finger domain protein 2B/0.506
4nyw2O3CREB-binding protein/0.502
4nra2LWBromodomain adjacent to zinc finger domain protein 2B/0.500
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.499
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.497
4ia3BIVVitamin D3 receptor A/0.495
1txiTX5Vitamin D3 receptor/0.494
1kqwRTLCellular retinol-binding protein type II/0.493
1pl8NADSorbitol dehydrogenase1.1.1.140.491
3vt7VDXVitamin D3 receptor/0.491
1unlRRCCyclin-dependent-like kinase 52.7.11.10.490
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.490
4nyv15ECREB-binding protein/0.489
4cdmFO1Deoxyribodipyrimidine photolyase/0.488
3oibFDAPutative acyl-CoA dehydrogenase/0.487
2xvw9NRSerum albumin/0.486
2wotZZGTGF-beta receptor type-12.7.11.300.485
4e960NSBromodomain-containing protein 4/0.485
4nr82LLBromodomain-containing protein 4/0.485
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.484
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.484
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.484
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.483
3kpzZNEVitamin D3 receptor/0.483
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.483
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.482
4nqnY1ZBromodomain-containing protein 9/0.482
3mykANPMyosin-2 heavy chain/0.481
4jxrACOAcetyltransferase/0.481
4qa2SHHHistone deacetylase 83.5.1.980.481
2x7jTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.480
3vt8YI3Vitamin D3 receptor/0.480
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.480
4nb6444Nuclear receptor ROR-gamma/0.480
4qzuRTLRetinol-binding protein 2/0.480
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.480
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.480
3sn6P0GBeta-2 adrenergic receptor/0.480
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.479
3w78CBDFMN-dependent NADH-azoreductase/0.479
3vrwYS5Vitamin D3 receptor/0.478
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.478
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.478
4pnmNU1Tankyrase-22.4.2.300.478
5eccNAPDehydrofolate reductase type I/0.478
2bxqIMNSerum albumin/0.477
3vruYS3Vitamin D3 receptor/0.477
4an4DUDPutative glycosyl transferase/0.477
4hxm1A8Bromodomain-containing protein 4/0.477
4m10ICDProstaglandin G/H synthase 21.14.99.10.477
4mv8ACPBiotin carboxylase6.3.4.140.477
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.476
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.476
4caxMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.476
1jtqLY3Thymidylate synthase/0.474
1p0hACOMycothiol acetyltransferase2.3.1.1890.474
1y4lSVRBasic phospholipase A2 homolog 2/0.474
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.474
2bunFADAppA protein/0.474
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.474
3dds26BGlycogen phosphorylase, liver form2.4.1.10.474
3dr1C5DVitamin D3 receptor A/0.474
3h4vNAPPteridine reductase 11.5.1.330.474
3lshFADPyranose 2-oxidase/0.474
1h63FMNPentaerythritol tetranitrate reductase/0.473
1ppjANYCytochrome b/0.473
2abbFMNPentaerythritol tetranitrate reductase/0.473
2hb8MVDVitamin D3 receptor/0.473
2lzg13QE3 ubiquitin-protein ligase Mdm26.3.20.473
3a783EVVitamin D3 receptor/0.473
3exnACOProbable acetyltransferase/0.473
3nga3NGCasein kinase II subunit alpha2.7.11.10.473
3w0yDS4Vitamin D3 receptor/0.473
5kp2COA3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2/0.473
2p4yC03Peroxisome proliferator-activated receptor gamma/0.472
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.472
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.472
3cgdCOACoenzyme A disulfide reductase/0.472
4bfvZVVPantothenate kinase2.7.1.330.472
1f4fTP3Thymidylate synthase/0.471
1fmlRTLRetinol dehydratase/0.471
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.471
2hamC33Vitamin D3 receptor/0.471
2xlsFADPutative flavin-containing monooxygenase/0.471
2xvv9DNSerum albumin/0.471
3vt5YI2Vitamin D3 receptor/0.471
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.471
4wkqIREEpidermal growth factor receptor2.7.10.10.471
2b7aIZATyrosine-protein kinase JAK2/0.470
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.470
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.470
3inxJZCHeat shock protein HSP 90-alpha/0.470
4c02TAKActivin receptor type-12.7.11.300.470
4dijBLFE3 ubiquitin-protein ligase Mdm26.3.20.470
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.470
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.470
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.469
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.469
3mtlFEFCyclin-dependent kinase 162.7.11.220.469
3wowANPCasein kinase II subunit alpha2.7.11.10.469
4bj9UHBTankyrase-22.4.2.300.469
4g1z0VPVitamin D3 receptor A/0.469
4g8bHL6Alpha/beta hydrolase fold protein/0.469
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.468
1lriCLRBeta-elicitin cryptogein/0.468
2pulACPMethylthioribose kinase2.7.1.1000.468
2qo9ANPEphrin type-A receptor 32.7.10.10.468
2v58LZJBiotin carboxylase6.3.4.140.468
2zjwREFCasein kinase II subunit alpha2.7.11.10.468
3zh8C58Protein kinase C iota type2.7.11.130.468
4ia7BIVVitamin D3 receptor A/0.468
4itfTFYVitamin D3 receptor/0.468
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.467
3fwjCAMCamphor 5-monooxygenase1.14.15.10.467
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.467
3lsiFADPyranose 2-oxidase/0.467
3wffWFFMineralocorticoid receptor/0.467
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
4egnTWOCytochrome P450/0.467
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.467
4iteTEYVitamin D3 receptor/0.467
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.467
4kb81QNCasein kinase I isoform delta2.7.11.10.467
5dn3ATPAurora kinase A2.7.11.10.467
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.466
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.466
1ndzFR5Adenosine deaminase3.5.4.40.466
1rfuADPPyridoxal kinase2.7.1.350.466
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.466
2cchATPCyclin-dependent kinase 22.7.11.220.466
2j9gANPBiotin carboxylase6.3.4.140.466
3cgcCOACoenzyme A disulfide reductase/0.466
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.466
4jqeANPCasein kinase II subunit alpha2.7.11.10.466
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.466
1synF89Thymidylate synthase/0.465
1t88CAMCamphor 5-monooxygenase1.14.15.10.465
1x8lOXRRetinol dehydratase/0.465
2c27ACOMycothiol acetyltransferase2.3.1.1890.465
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.465
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.465
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.465
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.465
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.465
3emlZMAAdenosine receptor A2a/0.465
1ie9VDXVitamin D3 receptor/0.464
1rx8NAPDihydrofolate reductase1.5.1.30.464
1s0zEB1Vitamin D3 receptor/0.464
1t79DHTAndrogen receptor/0.464
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.464
2a3iC0RMineralocorticoid receptor/0.464
2bxmIMNSerum albumin/0.464
2yeiXQIHeat shock protein HSP 90-alpha/0.464
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.464
3nszANPCasein kinase II subunit alpha2.7.11.10.464
4dymIYZActivin receptor type-12.7.11.300.464
4i8vBHFCytochrome P450 1A11.14.14.10.464
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.464
4m8e29VRetinoic acid receptor RXR-alpha/0.464
1cqp803Integrin alpha-L/0.463
1likADNAdenosine kinase2.7.1.200.463
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
2cig1DGDihydrofolate reductase1.5.1.30.463
2harOCCVitamin D3 receptor/0.463
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.463
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.463
3r5zF42Uncharacterized protein/0.463
3sp9IL2Peroxisome proliferator-activated receptor delta/0.463
3w5rLOAVitamin D3 receptor/0.463
4ap3FADSteroid monooxygenase/0.463
4eiyZMAAdenosine receptor A2a/0.463
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4jubTPPBenzoylformate decarboxylase4.1.1.70.463
4prvADPDNA gyrase subunit B/0.463
5e8wSTUTGF-beta receptor type-12.7.11.300.463
1bsvNDPGDP-L-fucose synthase/0.462
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
1m78NDPDihydrofolate reductase1.5.1.30.462
1nzfUPGDNA beta-glucosyltransferase/0.462
1rk3VDXVitamin D3 receptor/0.462
1uyhPU0Heat shock protein HSP 90-alpha/0.462
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.462
2tpsTPSThiamine-phosphate synthase/0.462
3csdEMOPutative ketoacyl reductase1.3.10.462
3gb4D3MDdmC/0.462
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.462
3pqbVGPPutative oxidoreductase/0.462
3rnnRNNGlutamate receptor 2/0.462
3t1a5MAGag-Pol polyprotein2.7.7.490.462
1db1VDXVitamin D3 receptor/0.461
1h51FMNPentaerythritol tetranitrate reductase/0.461
1uy7PU4Heat shock protein HSP 90-alpha/0.461
2ovhAS0Progesterone receptor/0.461
2po7CHDFerrochelatase, mitochondrial4.99.1.10.461
2zb45OPProstaglandin reductase 21.3.1.480.461
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.461
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.461
3mnrSD1Heat shock protein HSP 90-alpha/0.461
3pe2E1BCasein kinase II subunit alpha2.7.11.10.461
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.461
3w0hW12Vitamin D3 receptor/0.461
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.461
4k9yK9YFocal adhesion kinase 12.7.10.20.461
4lfiGNPCasein kinase II subunit alpha2.7.11.10.461
5cvhADPCasein kinase II subunit alpha2.7.11.10.461
5k2aZMAAdenosine receptor A2a/0.461
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.460
1zys199Serine/threonine-protein kinase Chk12.7.11.10.460
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.460
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.460
2pvkP45Casein kinase II subunit alpha2.7.11.10.460
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.460
2v5aLZLBiotin carboxylase6.3.4.140.460
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.460
3ft8MOJHeat shock protein HSP 90-alpha/0.460
3h6vNS6Glutamate receptor 2/0.460
3w0c6DSVitamin D3 receptor/0.460
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.460
4c57FEFCyclin-G-associated kinase2.7.11.10.460
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.460
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.460
4jq4IMNAldo-keto reductase family 1 member C2/0.460
4riyADPEpidermal growth factor receptor2.7.10.10.460
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.459
1itzTPPTransketolase, chloroplastic2.2.1.10.459
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.459
2ittAEEEpidermal growth factor receptor2.7.10.10.459
2p1u4TNRetinoic acid receptor RXR-alpha/0.459
3cgeCOACoenzyme A disulfide reductase/0.459
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.459
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.459
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.459
4oal245Cytokinin dehydrogenase 4/0.459
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.459
5ikqJMSProstaglandin G/H synthase 21.14.99.10.459
1ie8KH1Vitamin D3 receptor/0.458
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.458
1rkhVD2Vitamin D3 receptor/0.458
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.458
2hcdBIVVitamin D3 receptor A/0.458
2l84J28CREB-binding protein/0.458
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.458
3r354CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.458
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.458
4g8zTOPDihydrofolate reductase1.5.1.30.458
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.458
4ixgIXGDihydrofolate reductase1.5.1.30.458
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.458
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.458
4y8wSTRSteroid 21-hydroxylase/0.458
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.457
1phgMYTCamphor 5-monooxygenase1.14.15.10.457
1v7aFRCAdenosine deaminase3.5.4.40.457
1wn3HXCPhenylacetic acid degradation protein PaaI/0.457
1y0s331Peroxisome proliferator-activated receptor delta/0.457
2jfz003Glutamate racemase/0.457
2jkkBI9Focal adhesion kinase 12.7.10.20.457
2oaxSNLMineralocorticoid receptor/0.457
2q5oPPYIndole-3-pyruvate decarboxylase4.1.1.740.457
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.457
3c6uM22Gag-Pol polyprotein2.7.7.490.457
3ns2PYVAbscisic acid receptor PYL2/0.457
3vspEK8Peroxisome proliferator-activated receptor gamma/0.457
3vtdTKDVitamin D3 receptor/0.457
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.457
4eol1ROCyclin-dependent kinase 22.7.11.220.457
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.457
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.457
4prxADPDNA gyrase subunit B/0.457
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.456
1m2rMNYCasein kinase II subunit alpha2.7.11.10.456
1mj3HXCEnoyl-CoA hydratase, mitochondrial4.2.1.170.456
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1th6OINBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.456
2fhnBNIAvidin-related protein 4/5/0.456
2hasC3OVitamin D3 receptor/0.456
2y5s78HDihydropteroate synthase/0.456
3gobHXXDdmC/0.456
3njoP2MAbscisic acid receptor PYR1/0.456
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.456
3pe13NGCasein kinase II subunit alpha2.7.11.10.456
3rpv26ZCyclin-dependent kinase 22.7.11.220.456
3vt9YI4Vitamin D3 receptor/0.456
4awp99AHeat shock protein HSP 90-alpha/0.456
4brxKGWFocal adhesion kinase 12.7.10.20.456
4ejh0QACytochrome P450 2A131.14.14.10.456
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.456
4jqh1MFAlr2278 protein/0.456
4pkl1GHUncharacterized protein/0.456
4ruoBIVVitamin D3 receptor A/0.456
4tuvCPZCytochrome P450 1191.140.456
4ure1PSCyclohexanol dehydrogenase/0.456
1iyzNDPProbable quinone oxidoreductase/0.455
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.455
1p0pBCHCholinesterase3.1.1.80.455
1t87CAMCamphor 5-monooxygenase1.14.15.10.455
1wlvCOAPhenylacetic acid degradation protein PaaI/0.455
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.455
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
2dwbANPAurora kinase A2.7.11.10.455
2hb7O1CVitamin D3 receptor/0.455
2izrBRKCasein kinase I isoform gamma-32.7.11.10.455
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
2pvlP55Casein kinase II subunit alpha2.7.11.10.455
2x7hPFNProstaglandin reductase 310.455
3gxlQIGTGF-beta receptor type-12.7.11.300.455
3owsEQUSteroid Delta-isomerase5.3.3.10.455
3p8jFMNPentaerythritol tetranitrate reductase/0.455
3s7a684Dihydrofolate reductase1.5.1.30.455
3w32W32Epidermal growth factor receptor2.7.10.10.455
3wrlCAMCamphor 5-monooxygenase1.14.15.10.455
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4e4m0NHTyrosine-protein kinase JAK2/0.455
4fyo0VFTyrosine-protein kinase SYK2.7.10.20.455
4fz70VHTyrosine-protein kinase SYK2.7.10.20.455
4ia1BIVVitamin D3 receptor A/0.455
4kb81QOCasein kinase I isoform delta2.7.11.10.455
4kba1QMCasein kinase I isoform delta2.7.11.10.455
4l8u9AZSerum albumin/0.455
4lxhC1EAlpha/beta hydrolase fold/0.455
4nmbFADBifunctional protein PutA/0.455
5h8tRTLRetinol-binding protein 1/0.455
1crbRTLRetinol-binding protein 1/0.454
1g28FMNPHY3/0.454
1kmvLIIDihydrofolate reductase1.5.1.30.454
1nq14HYThyroid hormone receptor beta/0.454
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.454
1s19MC9Vitamin D3 receptor/0.454
1tl7FOKAdenylate cyclase type 2/0.454
1tl7FOKAdenylate cyclase type 5/0.454
1v79FR7Adenosine deaminase3.5.4.40.454
1zrzBI1Protein kinase C iota type2.7.11.130.454
2aa2AS4Mineralocorticoid receptor/0.454
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.454
2ftoTMPThymidylate synthase/0.454
2vwz7X6Ephrin type-B receptor 42.7.10.10.454
2w06FRVCyclin-dependent kinase 22.7.11.220.454
2xneASHAurora kinase A2.7.11.10.454
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.454
3cukFADD-amino-acid oxidase1.4.3.30.454
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.454
3gwfFADCyclohexanone monooxygenase/0.454
3ibqATPPyridoxal kinase/0.454
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.454
3qm4PN0Cytochrome P450 2D6/0.454
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.454
3vrvYSDVitamin D3 receptor/0.454
4do30LAFatty-acid amide hydrolase 13.5.1.990.454
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4fr0SAMArsenic methyltransferase/0.454
4nbb9CATerminal oxygenase component of carbazole/0.454
4r1lADPPhenylacetate-coenzyme A ligase/0.454
4tjy3GNTankyrase-22.4.2.300.454
1phePIYCamphor 5-monooxygenase1.14.15.10.453
1u7tTDT3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.453
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.453
2fwzH71Heat shock protein HSP 90-alpha/0.453
2hw2RFPRifampin ADP-ribosyl transferase/0.453
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.453
2q5oTPWIndole-3-pyruvate decarboxylase4.1.1.740.453
2vzzSCAPutative succinyl-CoA transferase Rv0802c2.8.30.453
3b9lAZZSerum albumin/0.453
3iaeD7KBenzaldehyde lyase/0.453
3lqfNADGalactitol dehydrogenase/0.453
3nr4PYVAbscisic acid receptor PYL2/0.453
3qdd94MHeat shock protein HSP 90-alpha/0.453
3s1dZIRCytokinin dehydrogenase 11.5.99.120.453
3s2pPMUCyclin-dependent kinase 22.7.11.220.453
3w0gW07Vitamin D3 receptor/0.453
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.453
4aoxFADSteroid monooxygenase/0.453
4dgo0JWCasein kinase II subunit alpha2.7.11.10.453
4enhFVXCholesterol 24-hydroxylase/0.453
4eor4SPCyclin-dependent kinase 22.7.11.220.453
4fhh0U3Vitamin D3 receptor A/0.453
4g20484Vitamin D3 receptor A/0.453
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.453
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.453
4rujVDXVitamin D3 receptor A/0.453
4zs2FLUAlpha-ketoglutarate-dependent dioxygenase FTO/0.453
1dr3HBIDihydrofolate reductase1.5.1.30.452
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
1fbyREARetinoic acid receptor RXR-alpha/0.452
1ia1NDPDihydrofolate reductase1.5.1.30.452
1j39UPGDNA beta-glucosyltransferase/0.452
1m13HYFNuclear receptor subfamily 1 group I member 2/0.452
2pvnP63Casein kinase II subunit alpha2.7.11.10.452
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.452
3cppCAMCamphor 5-monooxygenase1.14.15.10.452
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.452
3l8p0CEAngiopoietin-1 receptor2.7.10.10.452
3mtfA3FActivin receptor type-12.7.11.300.452
3nhwZXZRibosyldihydronicotinamide dehydrogenase [quinone]/0.452
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.452
3opdHIEHeat shock protein 83/0.452
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.452
4fi1ATPCasein kinase II subunit alpha2.7.11.10.452
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
4hy6FJ1Heat shock protein HSP 90-alpha/0.452
4jq8KJ8Epidermal growth factor receptor2.7.10.10.452
5k2cZMAAdenosine receptor A2a/0.452
5uviZMAAdenosine receptor A2a/0.452
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.451
1bwsNDPGDP-L-fucose synthase/0.451
1eyqNARChalcone--flavonone isomerase 15.5.1.60.451
1fxsNAPGDP-L-fucose synthase/0.451
1gebCAMCamphor 5-monooxygenase1.14.15.10.451
1o5rFR9Adenosine deaminase3.5.4.40.451
1rx8FOLDihydrofolate reductase1.5.1.30.451
1tvoFRZMitogen-activated protein kinase 12.7.11.240.451
1uy8PU5Heat shock protein HSP 90-alpha/0.451
1zeoC01Peroxisome proliferator-activated receptor gamma/0.451
2bkzSBCCyclin-dependent kinase 22.7.11.220.451
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.451
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.451
2itvANPEpidermal growth factor receptor2.7.10.10.451
2kceD16Thymidylate synthase/0.451
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.451
2pvmP29Casein kinase II subunit alpha2.7.11.10.451
2vd5BI8Myotonin-protein kinase2.7.11.10.451
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.451
2wouZZFTGF-beta receptor type-12.7.11.300.451
3eljGS7Mitogen-activated protein kinase 82.7.11.240.451
3igoANPCalmodulin-domain protein kinase 1, putative/0.451
3m7rVDXVitamin D3 receptor/0.451
3ue6FMNAureochrome1/0.451
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.451
4kne1CYDihydrofolate reductase1.5.1.30.451
4l0qNADAlcohol dehydrogenase class-3/0.451
4pdaCTNNucleoside permease/0.451
5aluHD2Bifunctional epoxide hydrolase 23.1.3.760.451
1axwMTXThymidylate synthase/0.450
1dkfBMSRetinoic acid receptor alpha/0.450
1eioGCHGastrotropin/0.450
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1lf3EH5Plasmepsin-23.4.23.390.450
1rjkVDZVitamin D3 receptor/0.450
1t86CAMCamphor 5-monooxygenase1.14.15.10.450
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.450
1uykPUXHeat shock protein HSP 90-alpha/0.450
1xpqFADPolyamine oxidase FMS1/0.450
2amb17HAndrogen receptor/0.450
2c31ADPOxalyl-CoA decarboxylase4.1.1.80.450
2c96ATPPsp operon transcriptional activator/0.450
2fpcSCGStrictosidine synthase4.3.3.20.450
2h94FADLysine-specific histone demethylase 1A10.450
2hl0A3SThreonine--tRNA ligase6.1.1.30.450
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.450
2pmoHMDProtein kinase 7/0.450
2q5qTPWIndole-3-pyruvate decarboxylase4.1.1.740.450
2vx07X7Ephrin type-B receptor 42.7.10.10.450
2ykiYKIHeat shock protein HSP 90-alpha/0.450
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3bnkFMNFlavoredoxin/0.450
3h3r14HCollagen type IV alpha-3-binding protein/0.450
3kjm245Cytokinin dehydrogenase 11.5.99.120.450
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.450
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.450
3t8vBTJM1 family aminopeptidase3.4.110.450
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.450
3uvvREARetinoic acid receptor RXR-alpha/0.450
3w5tLHPVitamin D3 receptor/0.450
4anmWULCasein kinase II subunit alpha2.7.11.10.450
4asyN5YGlucose-1-phosphate thymidylyltransferase/0.450
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.450
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4feyADPPhosphoglycerate kinase/0.450
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.450
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.450
4utdACPAurora kinase A2.7.11.10.450
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.449
1dr5NAPDihydrofolate reductase1.5.1.30.449
1opbRETRetinol-binding protein 2/0.449
1rx1NAPDihydrofolate reductase1.5.1.30.449
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.449
2vcmM11Isopenicillin N synthase1.21.3.10.449
2z97CAMCamphor 5-monooxygenase1.14.15.10.449
2zbaZBATrichothecene 3-O-acetyltransferase/0.449
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.449
3bqcEMOCasein kinase II subunit alpha2.7.11.10.449
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
3oquA8SAbscisic acid receptor PYL9/0.449
3r374CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.449
3u8w09JMitogen-activated protein kinase 14/0.449
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.449
3zv5BPYCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.449
4bftZVTPantothenate kinase2.7.1.330.449
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.449
4eevL1XHepatocyte growth factor receptor2.7.10.10.449
4i22IREEpidermal growth factor receptor2.7.10.10.449
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.449
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.449
4mwhATPCasein kinase II subunit alpha2.7.11.10.449
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.449
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.449
4wluNADMalate dehydrogenase, mitochondrial1.1.1.370.449
5kghACOPredicted acetyltransferase/0.449
1b87ACOAac(6')-Ii protein/0.448
1cdeGARPhosphoribosylglycinamide formyltransferase/0.448
1d3gBREDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.448
1f4gTP4Thymidylate synthase/0.448
1oc1ASVIsopenicillin N synthase1.21.3.10.448
2bglNAJSecoisolariciresinol dehydrogenase1.1.1.3310.448
2i40BLZCyclin-dependent kinase 22.7.11.220.448
2ibtNEAModification methylase TaqI2.1.1.720.448
2itnANPEpidermal growth factor receptor2.7.10.10.448
2vr1ATFBiotin carboxylase6.3.4.140.448
2vx17X8Ephrin type-B receptor 42.7.10.10.448
2w3vTOPDihydrofolate reductase/0.448
2wi4ZZ4Heat shock protein HSP 90-alpha/0.448
3k4nFADPyranose 2-oxidase/0.448
3n6uTSUHTH-type transcriptional regulator TsaR/0.448
3q5kD1UHeat shock protein 83-1/0.448
3up3XCAaceDAF-12/0.448
3wfgWFGMineralocorticoid receptor/0.448
4awo99BHeat shock protein HSP 90-alpha/0.448
4m11MXMProstaglandin G/H synthase 21.14.99.10.448
4obuPLPPyridoxal-dependent decarboxylase domain protein/0.448
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.448
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.448
4zp1TPPPyruvate decarboxylase4.1.1.10.448
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.448
5dr2ATPAurora kinase A2.7.11.10.448
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1kzjCB3Thymidylate synthase/0.447
1luaNAPBifunctional protein MdtA1.5.1.50.447
1m2qMNXCasein kinase II subunit alpha2.7.11.10.447
1pjkANPCasein kinase II subunit alpha2.7.11.10.447
1pxxDIFProstaglandin G/H synthase 21.14.99.10.447
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.447
1sn0T44Transthyretin/0.447
1v1aKDG2-dehydro-3-deoxygluconokinase2.7.1.450.447
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.447
2bakAQZMitogen-activated protein kinase 14/0.447
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.447
2fzjDH3Dihydrofolate reductase1.5.1.30.447
2g78REACellular retinoic acid-binding protein 2/0.447
2nn7M29Carbonic anhydrase 14.2.1.10.447
2p1v5TNRetinoic acid receptor RXR-alpha/0.447
2puiADPMethylthioribose kinase2.7.1.1000.447
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.447
3e7iB2Nitric oxide synthase, inducible1.14.13.390.447
3eej53RUncharacterized protein/0.447
3gggNADPrephenate dehydrogenase/0.447
3glmCOOGlutaconyl-CoA decarboxylase alpha subunit/0.447
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
3i8aN22Dihydrofolate reductase1.5.1.30.447
3iok1P6Tyrosine-protein kinase JAK2/0.447
3mb714ICasein kinase II subunit alpha2.7.11.10.447
3pyy3YYTyrosine-protein kinase ABL12.7.10.20.447
3q9xEMOCasein kinase II subunit alpha2.7.11.10.447
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4a9yAQZMitogen-activated protein kinase 14/0.447
4cgjNZLIntegrase/0.447
4fhi0S4Vitamin D3 receptor A/0.447
4fko20KCyclin-dependent kinase 22.7.11.220.447
4g2i0VQVitamin D3 receptor/0.447
4g95OAGDihydrofolate reductase1.5.1.30.447
4gub0Y4Casein kinase II subunit alpha2.7.11.10.447
4i6gFADCryptochrome-2/0.447
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.447
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.447
4k4eK4ETankyrase-12.4.2.300.447
4ocvANPAminoglycoside phosphotransferase/0.447
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.447
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.447
5cb4ACPTubulin tyrosine ligase/0.447
5k2bZMAAdenosine receptor A2a/0.447
1fmjRTLRetinol dehydratase/0.446
1gs4ZK5Androgen receptor/0.446
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1phhFADp-hydroxybenzoate hydroxylase/0.446
1qvnFRIInterleukin-2/0.446
1rkgVD1Vitamin D3 receptor/0.446
1uyePU9Heat shock protein HSP 90-alpha/0.446
1yc2NADNAD-dependent protein deacylase 2/0.446
1yrdCAMCamphor 5-monooxygenase1.14.15.10.446
2abi1CAMineralocorticoid receptor/0.446
2vgoAD5Aurora kinase B-A2.7.11.10.446
2vwy7X5Ephrin type-B receptor 42.7.10.10.446
2w6mOA1Biotin carboxylase6.3.4.140.446
2x9dITCTetracycline repressor protein class D/0.446
2zlcVDXVitamin D3 receptor/0.446
3bg7FADPyranose 2-oxidase/0.446
3gubGUBDeath-associated protein kinase 12.7.11.10.446
3litE15Protease/0.446
3m09RARDihydrofolate reductase1.5.1.30.446
3meeT27Gag-Pol polyprotein2.7.7.490.446
3ormAGSSerine/threonine protein kinase/0.446
3pd3A3TThreonine--tRNA ligase6.1.1.30.446
3pm0BHFCytochrome P450 1B1/0.446
3raiX85Cyclin-dependent kinase 22.7.11.220.446
3w0jT08Vitamin D3 receptor/0.446
4j6dTESCytochrome P450 monooxygenase/0.446
4jajXU1Aurora kinase A2.7.11.10.446
4kl9NDPDihydrofolate reductase1.5.1.30.446
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.446
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.446
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.446
5e8xSTUTGF-beta receptor type-12.7.11.300.446
3qakUKAAdenosine receptor A2a/0.446
1jlaTNKGag-Pol polyprotein2.7.7.490.445
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1ot7IU5Bile acid receptor/0.445
1uy6PU3Heat shock protein HSP 90-alpha/0.445
1uyuCAMCamphor 5-monooxygenase1.14.15.10.445
1x7gNAPPutative ketoacyl reductase1.3.10.445
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.445
2c6tDT5Cyclin-dependent kinase 22.7.11.220.445
2cy2ACOProbable acetyltransferase/0.445
2duv371Cyclin-dependent kinase 22.7.11.220.445
2gr0FADFerredoxin reductase/0.445
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.445
2iw84SPCyclin-dependent kinase 22.7.11.220.445
2ixaNADAlpha-N-acetylgalactosaminidase3.2.1.490.445
2o4jVD4Vitamin D3 receptor/0.445
2o4rVD5Vitamin D3 receptor/0.445
2ociTYCValacyclovir hydrolase3.10.445
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.445
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.445
2yee2ECHeat shock protein HSP 90-alpha/0.445
3axwTIDCasein kinase II subunit alpha2.7.11.10.445
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.445
3hz142CHeat shock protein HSP 90-alpha/0.445
3ia4MTXDihydrofolate reductase/0.445
3q3cNADNAD-dependent L-serine dehydrogenase/0.445
3srwQ27Dihydrofolate reductase1.5.1.30.445
3vs3VSETyrosine-protein kinase HCK2.7.10.20.445
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.445
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.445
4efuEFUHeat shock protein HSP 90-alpha/0.445
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.445
4h6rFDAProline dehydrogenase/0.445
4ly91YYGlucokinase regulatory protein/0.445
4nm9FADBifunctional protein PutA/0.445
4okt198Androgen receptor/0.445
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.445
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
5il2SAHN6-adenosine-methyltransferase 70 kDa subunit/0.445
5kgpACOPredicted acetyltransferase/0.445
1gij2PUCyclin-dependent kinase 22.7.11.220.444
1skgVAL_ALA_PHE_ARG_SERBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.444
1upw444Oxysterols receptor LXR-beta/0.444
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.444
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.444
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.444
2i0ePDSProtein kinase C beta type2.7.11.130.444
2oppHBQGag-Pol polyprotein2.7.7.490.444
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.444
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.444
2qblCAMCamphor 5-monooxygenase1.14.15.10.444
2w9hTOPDihydrofolate reductase1.5.1.30.444
2znnS44Peroxisome proliferator-activated receptor alpha/0.444
3cseN22Uncharacterized protein/0.444
3d0bSNXHeat shock protein HSP 90-alpha/0.444
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.444
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.444
3hz6ADPXylulokinase/0.444
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.444
3rk909ZCyclin-dependent kinase 22.7.11.220.444
3rvg17PTyrosine-protein kinase JAK2/0.444
3sf6FDAGlutaryl-CoA dehydrogenase/0.444
3v3vMYUMitogen-activated protein kinase 82.7.11.240.444
3w0oADPHygromycin-B 4-O-kinase2.7.1.1630.444
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.444
4dgnLU2Casein kinase II subunit alpha2.7.11.10.444
4eji0QACytochrome P450 2A131.14.14.10.444
4ho4THMGlucose-1-phosphate thymidylyltransferase/0.444
4iw8KN3Estrogen receptor/0.444
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.444
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.444
4zm6ACON-acetyl-beta-D glucosaminidase/0.444
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.443
1dhiMTXDihydrofolate reductase1.5.1.30.443
1g4tFTPThiamine-phosphate synthase/0.443
1pkfEPDEpothilone C/D epoxidase1.140.443
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.443
1ykdCMPAdenylate cyclase/0.443
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.443
2bbqPFGThymidylate synthase/0.443
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.443
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.443
2cyeCOAPutative thioesterase/0.443
2h55DZ8Heat shock protein HSP 90-alpha/0.443
2itzIREEpidermal growth factor receptor2.7.10.10.443
2pmlANPUncharacterized protein/0.443
2q7kTESAndrogen receptor/0.443
2v7a627Tyrosine-protein kinase ABL12.7.10.20.443
2w6oOA3Biotin carboxylase6.3.4.140.443
2wggTLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.443
2wi72KLHeat shock protein HSP 90-alpha/0.443
2znpK55Peroxisome proliferator-activated receptor delta/0.443
3at3ATKCasein kinase II subunit alpha2.7.11.10.443
3h4vDVPPteridine reductase 11.5.1.330.443
3hz5Z64Heat shock protein HSP 90-alpha/0.443
3ibeL64Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3inwJZBHeat shock protein HSP 90-alpha/0.443
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.443
3mdvCL6Cholesterol 24-hydroxylase/0.443
3o0iP54Heat shock protein HSP 90-alpha/0.443
3pj8404Cyclin-dependent kinase 22.7.11.220.443
3qiyQI1Botulinum neurotoxin type A3.4.24.690.443
3tk3CPZCytochrome P450 2B41.14.14.10.443
3vjoANPEpidermal growth factor receptor2.7.10.10.443
4a8v2ANMajor pollen allergen Bet v 1-J/0.443
4apuA2KProgesterone receptor/0.443
4asf62UATP-dependent molecular chaperone HSP82/0.443
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4fqsLYAThymidylate synthase ThyA/0.443
4h6kFMNNADPH dehydrogenase 11.6.99.10.443
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.443
4in44IDKelch-like ECH-associated protein 1/0.443
4ix6ADPUncharacterized protein/0.443
4l2yXXKPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.443
4mfb29TGag-Pol polyprotein2.7.7.490.443
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.443
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.443
4oauADP2-5A-dependent ribonuclease3.1.260.443
4pleCPSNuclear receptor subfamily 5 group A member 2/0.443
4qnaX11Serine/threonine-protein kinase 242.7.11.10.443
4r3kCOAN-alpha-acetyltransferase2.3.10.443
4rrlA3SProbable threonine--tRNA ligase 26.1.1.30.443
4rrxLURProstaglandin G/H synthase 21.14.99.10.443
4rtsSAMDNA adenine methylase2.1.1.720.443
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.443
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.443
6prcCEBReaction center protein L chain/0.443
5jtbZMAAdenosine receptor A2a/0.443
1ay0TPPTransketolase 12.2.1.10.442
1cx2S58Prostaglandin G/H synthase 21.14.99.10.442
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.442
1drhNAPDihydrofolate reductase1.5.1.30.442
1fkwPURAdenosine deaminase3.5.4.40.442
1jioDEB6-deoxyerythronolide B hydroxylase/0.442
1n5qTNCActVA 6 protein/0.442
1tehNADAlcohol dehydrogenase class-31.1.1.10.442
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.442
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.442
2oz6CMPCyclic AMP receptor-like protein/0.442
2qboCAMCamphor 5-monooxygenase1.14.15.10.442
2wd9IBPAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.442
2ylxFADPhenylacetone monooxygenase1.14.13.920.442
2z3uCRRCytochrome P450/0.442
3a0iAJIGlucokinase2.7.1.20.442
3be9P04Casein kinase II subunit alpha2.7.11.10.442
3bfb9ODPheromone-binding protein ASP1/0.442
3bhy7CPDeath-associated protein kinase 3/0.442
3dogNNNCyclin-dependent kinase 22.7.11.220.442
3ih0ANPUncharacterized sugar kinase PH14592.7.10.442
3mqe416Prostaglandin G/H synthase 21.14.99.10.442
3negPYVAbscisic acid receptor PYL1/0.442
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.442
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.442
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.442
3pxyJWSCyclin-dependent kinase 22.7.11.220.442
3qlrNDPDihydrofolate reductase1.5.1.30.442
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.442
3tjsD0RCytochrome P450 3A4/0.442
3u4uLNHCasein kinase II subunit alpha2.7.11.10.442
3vg9ZMAAdenosine receptor A2a/0.442
3vt3VDXVitamin D3 receptor/0.442
3wd7COAAcridone synthase/0.442
3zrbOR8Progesterone receptor/0.442
4acm7YGCyclin-dependent kinase 22.7.11.220.442
4ap7F47Hepatocyte growth factor receptor2.7.10.10.442
4at2ASDPossible succinate dehydrogenase/0.442
4b4oNDPEpimerase family protein SDR39U1/0.442
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4fkpLS5Cyclin-dependent kinase 22.7.11.220.442
4fkr45KCyclin-dependent kinase 22.7.11.220.442
4g3rCAMCamphor 5-monooxygenase1.14.15.10.442
4i9i1DYTankyrase-12.4.2.300.442
4ifn12OKelch-like ECH-associated protein 1/0.442
4jr7GNPCasein kinase II subunit alpha2.7.11.10.442
4k4j1O8Retinoic acid receptor RXR-alpha/0.442
4nh82LCHeat shock protein HSP 90-alpha/0.442
4rupH97Vitamin D3 receptor A/0.442
4yswFADXanthine dehydrogenase/oxidase/0.442
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
5auzGENDeath-associated protein kinase 12.7.11.10.442
5e8ySTUTGF-beta receptor type-22.7.11.300.442
1blzACVIsopenicillin N synthase1.21.3.10.441
1ckpPVBCyclin-dependent kinase 22.7.11.220.441
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1h1r6CPCyclin-dependent kinase 22.7.11.220.441
1i59ADPChemotaxis protein CheA2.7.13.30.441
1iwjCAMCamphor 5-monooxygenase1.14.15.10.441
1ke6LS2Cyclin-dependent kinase 22.7.11.220.441
1kl2FONSerine hydroxymethyltransferase/0.441
1lp4ANPCasein kinase II subunit alpha2.7.11.10.441
1t1sCBQ1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.441
1u54ACPActivated CDC42 kinase 1/0.441
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.441
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.441
1xddAAYIntegrin alpha-L/0.441
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.441
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.441
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.441
2ftoCB3Thymidylate synthase/0.441
2gtk208Peroxisome proliferator-activated receptor gamma/0.441
2h39ADQADP-glucose phosphorylase/0.441
2iyaZIOOleandomycin glycosyltransferase/0.441
2izuP01Casein kinase I isoform gamma-32.7.11.10.441
2np8CC3Aurora kinase A2.7.11.10.441
2pmdGNPTranslation initiation factor 2 subunit gamma/0.441
2wghDTPRibonucleoside-diphosphate reductase large subunit1.17.4.10.441
2x4f16XMyosin light chain kinase family member 42.7.11.10.441
3ahiHTLProbable phosphoketolase/0.441
3bfa9ODOdorant binding protein ASP1/0.441
3cluFADElectron transfer flavoprotein subunit alpha/0.441
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.441
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.441
3eek53SUncharacterized protein/0.441
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
3gwnFADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.441
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.441
3lakKR1Gag-Pol polyprotein2.7.7.490.441
3mvm39PMitogen-activated protein kinase 14/0.441
3pdqKC6Lysine-specific demethylase 4A1.14.110.441
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
3r34COA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.441
3rusADPChaperonin/0.441
3t3r9PLCytochrome P450 2A61.14.130.441
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.441
3unj0BXCyclin-dependent kinase 22.7.11.220.441
3vt65YIVitamin D3 receptor/0.441
3w0aDS5Vitamin D3 receptor/0.441
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.441
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.441
4a2bAGSCell division protein FtsA/0.441
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4awq592Heat shock protein HSP 90-alpha/0.441
4c58824Cyclin-G-associated kinase2.7.11.10.441
4cukNAID-lactate dehydrogenase/0.441
4du82P0Mevalonate diphosphate decarboxylase/0.441
4e1z0MXNon-receptor tyrosine-protein kinase TYK22.7.10.20.441
4f700STCyclin-dependent kinase 82.7.11.220.441
4fgg0U5Dihydrofolate reductase1.5.1.30.441
4fv8E63Mitogen-activated protein kinase 12.7.11.240.441
4g210VPVitamin D3 receptor A/0.441
4hnc0UTMandelate racemase/0.441
4j7uYTZSepiapterin reductase1.1.1.1530.441
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.441
4l4cCAMCamphor 5-monooxygenase1.14.15.10.441
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.441
4n57ADPAPH(2'')-Id/0.441
4x2dATPFic family protein putative filamentation induced by cAMP protein/0.441
4xivADPChemotaxis protein CheA2.7.13.30.441
5cccDDFDihydrofolate reductase1.5.1.30.441
5cu6ATPCasein kinase II subunit alpha2.7.11.10.441
5iua6DXAdenosine receptor A2a/0.441
1bifAGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.440
1bwlFMNNADPH dehydrogenase 11.6.99.10.440
1g67TZPThiamine-phosphate synthase/0.440
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.440
1ie4T44Transthyretin/0.440
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.440
1kmsLIHDihydrofolate reductase1.5.1.30.440
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.440
1nhz486Glucocorticoid receptor/0.440
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.440
1oguST8Cyclin-dependent kinase 22.7.11.220.440
1py5PY1TGF-beta receptor type-12.7.11.300.440
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
2bfmTOPPteridine reductase 11.5.1.330.440
2c475IDCasein kinase I isoform gamma-2/0.440
2hc4VDXVitamin D3 receptor A/0.440
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2pd7FADVivid PAS protein VVD/0.440
2pmnK51Protein kinase 7/0.440
2uxoTACHTH-type transcriptional regulator TtgR/0.440
2vrbNAPTriphenylmethane reductase/0.440
2vwx7X4Ephrin type-B receptor 42.7.10.10.440
2w6zL21Biotin carboxylase6.3.4.140.440
2wkmPFYHepatocyte growth factor receptor2.7.10.10.440
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.440
2y6o1N1Ephrin type-A receptor 42.7.10.10.440
3cd2MTXDihydrofolate reductase1.5.1.30.440
3fwiCAMCamphor 5-monooxygenase1.14.15.10.440
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.440
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.440
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.440
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3m8p65BGag-Pol polyprotein2.7.7.490.440
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.440
3umw596Serine/threonine-protein kinase pim-12.7.11.10.440
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.440
4ax8ADPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.440
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.440
4bb432WEphrin type-B receptor 42.7.10.10.440
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
4bfsZVSPantothenate kinase2.7.1.330.440
4deeADPAurora kinase A2.7.11.10.440
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.440
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.440
4h9506UDihydrofolate reductase1.5.1.30.440
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.440
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.440
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.440
5cshATPCasein kinase II subunit alpha2.7.11.10.440
6cp4CAMCamphor 5-monooxygenase1.14.15.10.440
5k2dZMAAdenosine receptor A2a/0.440