sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4n4v	2GY	Tankyrase-1	2.4.2.30

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4n4v	2GY	Tankyrase-1	2.4.2.30	1.000
4mt9	2D6	Tankyrase-1	2.4.2.30	0.641
4n4t	2GV	Tankyrase-1	2.4.2.30	0.553
4msg	2C6	Tankyrase-1	2.4.2.30	0.542
4k4e	K4E	Tankyrase-1	2.4.2.30	0.525
4hyf	1AK	Tankyrase-2	2.4.2.30	0.512
4k4f	K4F	Tankyrase-1	2.4.2.30	0.512
4li8	1XQ	Tankyrase-1	2.4.2.30	0.500
4li7	1XP	Tankyrase-1	2.4.2.30	0.495
4bj9	UHB	Tankyrase-2	2.4.2.30	0.489
4tkg	09L	Tankyrase-2	2.4.2.30	0.481
4bfp	SWY	Tankyrase-2	2.4.2.30	0.479
4li6	1XO	Tankyrase-1	2.4.2.30	0.472
3u9y	09L	Tankyrase-2	2.4.2.30	0.455
4pnm	NU1	Tankyrase-2	2.4.2.30	0.452
4tjy	3GN	Tankyrase-2	2.4.2.30	0.441