sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4mv8	ACP	Biotin carboxylase	6.3.4.14

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4mv8	ACP	Biotin carboxylase	6.3.4.14	1.000
4mv1	ADP	Biotin carboxylase	6.3.4.14	0.568
2vr1	ATF	Biotin carboxylase	6.3.4.14	0.528
3jzf	JZK	Biotin carboxylase	6.3.4.14	0.516
2v5a	LZL	Biotin carboxylase	6.3.4.14	0.513
2v58	LZJ	Biotin carboxylase	6.3.4.14	0.503
2v59	LZK	Biotin carboxylase	6.3.4.14	0.503
2w6o	OA3	Biotin carboxylase	6.3.4.14	0.479
2w6z	L21	Biotin carboxylase	6.3.4.14	0.469
3g8d	ADP	Biotin carboxylase	6.3.4.14	0.468
2w6q	OA5	Biotin carboxylase	6.3.4.14	0.462
4mv4	ACP	Biotin carboxylase	6.3.4.14	0.458
2j9g	ANP	Biotin carboxylase	6.3.4.14	0.456
2w71	L23	Biotin carboxylase	6.3.4.14	0.442