sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4mrx | CZH | Obelin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4mrx | CZH | Obelin | / | 1.000 | |
| 4n1f | CZH | Obelin | / | 0.681 | |
| 1qv0 | CZH | Obelin | / | 0.656 | |
| 1el4 | CTZ | Obelin | / | 0.633 | |
| 1jf2 | CZH | Obelin | / | 0.626 | |
| 1qv1 | CZH | Obelin | / | 0.618 | |
| 1jf0 | CZH | Obelin | / | 0.614 | |
| 1uhh | CZP | Aequorin-2 | / | 0.601 | |
| 1s36 | CEI | Obelin | / | 0.599 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.594 | |
| 4nqg | CZH | Mitrocomin | / | 0.555 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.541 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.515 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.506 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.505 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.505 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.504 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.504 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.498 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.492 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.489 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.488 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.488 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.487 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.487 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.486 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.486 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 3o9l | LPN | Renin | 3.4.23.15 | 0.485 | |
| 4u95 | MIY | Multidrug efflux pump subunit AcrB | / | 0.485 | |
| 3fu8 | 3DM | Laccase-1 | 1.10.3.2 | 0.484 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.484 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.484 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.484 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.484 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.483 | |
| 4n4t | 2GV | Tankyrase-1 | 2.4.2.30 | 0.483 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.482 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.481 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.481 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.480 | |
| 3hyw | DCQ | Sulfide-quinone reductase | / | 0.480 | |
| 4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.479 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.478 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.478 | |
| 3hth | PRL | EbrA repressor | / | 0.478 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.477 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.476 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.475 | |
| 3up3 | XCA | aceDAF-12 | / | 0.475 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.474 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.474 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.474 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.474 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.474 | |
| 2g7y | MO9 | Cathepsin S | 3.4.22.27 | 0.473 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.473 | |
| 3htj | ET | EbrA repressor | / | 0.473 | |
| 3l71 | AZO | Cytochrome b | / | 0.473 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.473 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.472 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.472 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.471 | |
| 2vz0 | D64 | Pteridine reductase | / | 0.471 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.471 | |
| 5cto | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.471 | |
| 1sjw | NGV | Nogalonic acid methyl ester cyclase | / | 0.470 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.470 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.470 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.470 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 2vcg | S17 | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.469 | |
| 2yhu | WHF | Pteridine reductase | / | 0.469 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.469 | |
| 4hut | ATP | Cob(I)yrinic acid a,c-diamide adenosyltransferase | 2.5.1.17 | 0.469 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.468 | |
| 4kyk | IMN | Lactoylglutathione lyase | 4.4.1.5 | 0.468 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 3p9t | TCL | Repressor | / | 0.467 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.467 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.467 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.465 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.465 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.465 | |
| 3bmn | AX3 | Pteridine reductase | / | 0.464 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.464 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.463 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.463 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.463 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.462 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 2bxo | OPB | Serum albumin | / | 0.461 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.461 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.461 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.460 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.460 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.460 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.460 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.460 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.460 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.460 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.459 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.459 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.459 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.459 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 2acw | UPG | Glycosyltransferase | / | 0.458 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.458 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.458 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.458 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.458 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.457 | |
| 3f0r | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.457 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
| 1tg5 | 645 | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.456 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2qjp | ANJ | Cytochrome b | / | 0.456 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.456 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.456 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.455 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.455 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.454 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.454 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.454 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.454 | |
| 1mlz | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.453 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3zg6 | APR | NAD-dependent protein deacetylase sirtuin-6 | 3.5.1 | 0.453 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4gqk | ADP | Actin cross-linking toxin VgrG1 | / | 0.453 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.453 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.452 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 3r94 | FLR | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.452 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.452 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.451 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.451 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.451 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 3t31 | DCQ | Sulfide-quinone reductase | / | 0.451 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.451 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.451 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3fnu | 006 | HAP protein | / | 0.450 | |
| 3iiu | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.450 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 2x9g | LYA | Pteridine reductase | / | 0.449 | |
| 3jt4 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.449 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1e2l | TMC | Thymidine kinase | / | 0.448 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.448 | |
| 2fq6 | P3F | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.448 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.448 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
| 2zoz | ET | Transcriptional regulator | / | 0.448 | |
| 3gi2 | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3hx3 | RET | Retinaldehyde-binding protein 1 | / | 0.448 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.448 | |
| 4nbi | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.448 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.447 | |
| 1s07 | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.447 | |
| 1swg | BTN | Streptavidin | / | 0.447 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2zit | NAD | Exotoxin A | 2.4.2.36 | 0.447 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.447 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.447 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
| 4iah | 1DX | Alr2278 protein | / | 0.447 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.446 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.446 | |
| 2yiu | SMA | Cytochrome b | / | 0.446 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.446 | |
| 3r58 | NPS | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.446 | |
| 4pv5 | CBW | Lactoylglutathione lyase | 4.4.1.5 | 0.446 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.445 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 2hzq | STR | Apolipoprotein D | / | 0.445 | |
| 4li7 | 1XP | Tankyrase-1 | 2.4.2.30 | 0.445 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.445 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.445 | |
| 1k8z | IAG | Tryptophan synthase alpha chain | / | 0.444 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.444 | |
| 1u72 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.444 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.444 | |
| 3dko | IHZ | Ephrin type-A receptor 7 | 2.7.10.1 | 0.444 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3ox2 | 79X | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.444 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4wlj | IK2 | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.444 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.443 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1tfz | 869 | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.443 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.443 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.443 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.443 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.442 | |
| 2h7j | H7J | Cathepsin S | 3.4.22.27 | 0.442 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 2vbv | FMN | Riboflavin kinase | 2.7.1.161 | 0.442 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.442 | |
| 4dm8 | REA | Retinoic acid receptor beta | / | 0.442 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 5k8b | PDG | 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase | / | 0.442 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.441 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.441 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.441 | |
| 2mm3 | CHO | Gastrotropin | / | 0.441 | |
| 3jq6 | DX1 | Pteridine reductase, putative | / | 0.441 | |
| 3nos | H4B | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.441 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.441 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 4iae | 1DX | Alr2278 protein | / | 0.441 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 1ddt | APU | Diphtheria toxin | / | 0.440 | |
| 1pj7 | FFO | Dimethylglycine oxidase | 1.5.3.10 | 0.440 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.440 | |
| 1rti | HEF | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.440 | |
| 2eju | SAH | tRNA (guanine(26)-N(2))-dimethyltransferase | / | 0.440 | |
| 3jq9 | AX1 | Pteridine reductase, putative | / | 0.440 | |
| 3jt3 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.440 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4e70 | N7I | Coniferyl alcohol 9-O-methyltransferase | / | 0.440 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4mm4 | 8PR | Na(+):neurotransmitter symporter (Snf family) | / | 0.440 |