sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 1.000 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.728 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.718 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.675 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.472 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.471 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.458 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.449 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.441 |