sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4mht	SAH	Modification methylase HhaI	2.1.1.37

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4mht	SAH	Modification methylase HhaI	2.1.1.37	1.000
2z6u	SAH	Modification methylase HhaI	2.1.1.37	0.659
7mht	SAH	Modification methylase HhaI	2.1.1.37	0.634
9mht	SAH	Modification methylase HhaI	2.1.1.37	0.618
1skm	SAH	Modification methylase HhaI	2.1.1.37	0.587
8mht	SAH	Modification methylase HhaI	2.1.1.37	0.584
1fjx	SAH	Modification methylase HhaI	2.1.1.37	0.567
2i9k	SAH	Modification methylase HhaI	2.1.1.37	0.566
10mh	SAH	Modification methylase HhaI	2.1.1.37	0.558
2hmy	SAM	Modification methylase HhaI	2.1.1.37	0.473