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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4lsl1YQGag-Pol polyprotein2.7.7.49

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4lsl1YQGag-Pol polyprotein2.7.7.491.000
4h4m494Gag-Pol polyprotein2.7.7.490.589
3dokGWJPol protein/0.552
4h4o506Gag-Pol polyprotein2.7.7.490.548
4mfb29TGag-Pol polyprotein2.7.7.490.526
4rw6494Gag-Pol polyprotein2.7.7.490.520
2wonZZEGag-Pol polyprotein2.7.7.490.519
3t1a5MAGag-Pol polyprotein2.7.7.490.517
3lalKRVGag-Pol polyprotein2.7.7.490.516
3c6tM14Gag-Pol polyprotein2.7.7.490.514
3c6uM22Gag-Pol polyprotein2.7.7.490.513
2b5j3ACGag-Pol polyprotein2.7.7.490.505
3ffi3OBGag-Pol polyprotein2.7.7.490.503
2ynhEURGag-Pol polyprotein2.7.7.490.497
2be2R22Gag-Pol polyprotein2.7.7.490.492
3drpR8EGag-Pol polyprotein2.7.7.490.481
3lamKRPGag-Pol polyprotein2.7.7.490.480
4rw4494Gag-Pol polyprotein2.7.7.490.480
3is9AC7Gag-Pol polyprotein2.7.7.490.468
3dleGFAGag-Pol polyprotein2.7.7.490.465
2jleI15Reverse transcriptase/RNaseH/0.464
3dmjGWEPol protein/0.458
1c1bGCAGag-Pol polyprotein2.7.7.490.457
1c1c612Gag-Pol polyprotein2.7.7.490.451
1rt1MKCGag-Pol polyprotein2.7.7.490.445
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.442
3lanKBTGag-Pol polyprotein2.7.7.490.441